HPA Adapt

product on market Capsule Integrative Therapeutics 🟢 Safety: 100/100
Brand: Integrative Therapeutics
🟢 100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 33% of ingredients have research evidence
A Label Compliance Grade

Product Label

📄 Open Full PDF View on NIH DSLD →
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Label Data

2 Capsule(s) Serving Size
30 Servings
Botanical Product Type
33% Evidence Coverage

Supplement Facts — Evidence Check

Total Carbohydrates
1 Gram(s) (1% DV)
400 mg
📊 Market median: 300.0mg (122 products) 📚 22 studies (Tier A: 0, B: 7)
This product: 400mg
300 mg
📊 Market median: 450.0mg (502 products) 📚 28 studies (Tier A: 0, B: 8)
This product: 300mg
Eleuthero (Eleutherococcus senticosus) root extract
300 mg
200 mg
📊 Market median: 500.0mg (138 products) 📚 2 studies — no high-quality reviews
This product: 200mg
150 mg
📊 Market median: 500.0mg (357 products) 📚 1 studies — no high-quality reviews
This product: 150mg

Other Ingredients

Hydroxypropyl Methylcellulose Ascorbyl Palmitate Cellulose Silicon Dioxide

Label Claims — Verification

❓ All Other
❓ Structure/Function
All Other (98% of products) Structure/Function (80% of products) Nutrient (3% of products)

Target Groups

Vegetarian Adult (18 - 50 Years) Women (not pregnant or lactating) Gluten Free Dairy Free

Product Information

📋 Directions for Use

Recommendation: Adults take 2 to 4 capsules daily on an empty stomach, or as recommended by your healthcare professional. For best results take in the morning and at mid-day.

⚠️ Warnings & Precautions

Warning: Do not use if you are pregnant or under 18 years of age.

Do not use if you are pregnant or under 18 years of age. If you are nursing, diabetic, or taking any prescription drugs, consult your healthcare professional prior to use.

Keep out of reach of children.

Safety sealed with inner seal. Do not use if seal is broken or missing.

🧪 Formulation Notes

Contains no salt, wheat, gluten, soy, dairy products, ingredients of animal origin, or artificial colors, or flavors.

Stress Resistance Complex

Additional Information

Keep tightly closed. Store at room temperature. Avoid excessive heat and direct sunlight.

Quality Global Sourcing Bottled & Tested In The USA

Product Details

UPC / SKU 8 71791 10270 5
DSLD Entry Date 2021-03-25
Product Type Botanical
Form Capsule
Brand Integrative Therapeutics
DSLD ID 246428
Data Updated 2026-04-11

Research Evidence

39 Research Sources
51 Avg Quality Score
16 Rct
14 Systematic Review
5 Clinical Trial
4 Meta Analysis
B The efficacy and safety of Chinese herbal medicine, Rhodiola formulation in treating ischemic heart disease: a systematic review and meta-analysis of randomized controlled trials
Meta Analysis Complementary therapies in medicine 2014
PubMed DOI
B Clinical evidence for the adaptogenic effects of Withania somnifera and Rhodiola rosea - A systematic review with molecular interpretation of psychometric outcomes
Systematic Review Annals of agricultural and environmental medicine : AAEM 2026
PubMed DOI
B Efficacy and safety of Rhodiola crenulata extract in the treatment of acute high altitude disease, based on studies involving populations in China: A systematic review and meta-analysis
Systematic Review Frontiers in pharmacology 2025
PubMed DOI
B The Impact of Rhodiola Rosea Extract on Strength Performance in Alternative Bench-Press and Bench-Pull Exercises Under Resting and Mental Fatigue Conditions: A Randomized, Triple-Blinded, Placebo-Controlled, Crossover Trial
Rct Nutrients 2025
PubMed DOI
B Liver function monitoring: a prospective nested case-control study of Salvia miltiorrhiza polyphenol injection
Meta Analysis Scientific reports 2020
PubMed DOI
B A combination of green tea, rhodiola, magnesium and B vitamins modulates brain activity and protects against the effects of induced social stress in healthy volunteers
Rct Nutritional neuroscience 2022
PubMed DOI
B Standardized Rhodiola rosea injection for left ventricular remodeling and inflammation in patients with HFrEF: a systematic review and meta-analysis
Systematic Review Frontiers in pharmacology 2025
PubMed DOI
C Rhodiola rosea for physical and mental fatigue: a systematic review
Systematic Review BMC complementary and alternative medicine 2012
PubMed DOI
C Dazhu Hongjingtian Preparation as Adjuvant Therapy for Unstable Angina Pectoris: A Meta-Analysis of Randomized Controlled Trials
Systematic Review Frontiers in pharmacology 2020
PubMed DOI
C Understanding the research landscape of over-the-counter herbal products, dietary supplements, and medications evaluated for depressive symptoms in adults: a scoping review
Systematic Review Frontiers in pharmacology 2025
PubMed DOI
View all evidence for Rhodiola →

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