🟢 100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 50% of ingredients have research evidence
A Label Compliance Grade

Product Label

📸

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Label Data

5 Drop(s) Serving Size
30 Servings
Other Combinations Product Type
50% Evidence Coverage

Supplement Facts — Evidence Check

Calories
Total Carbohydrates
📊 Market median: 80.0mg (20 products) 📚 334 studies (Tier A: 8, B: 183)
This product: 16mg
📊 Market median: 400.0mg (142 products) 📚 10 studies (Tier A: 0, B: 2)
This product: 1mg

Other Ingredients

Rice bran oil Carnauba Wax

Label Claims — Verification

All Other
Structure/Function
All Other (99% of products) Structure/Function (91% of products) Nutrient (14% of products)

Target Groups

Infants/Baby (0 - 1 Year) Gluten Free Dairy Free

Product Information

📋 Directions for Use

Directions for 0-12 months: Shake before use. Use 5 drops once a day. Dispense onto a spoon, directly into baby's mouth, bottle or while breastfeeding. Replace cap with dropper. Once opened, use within 60 days.

⚠️ Warnings & Precautions

For questions, concerns or to report an adverse event, please call (800) 722-3476 www.Culturelle.com

Please consult your healthcare professional prior to use.

Warning: Keep out of reach of children. When first taking a probiotic, your baby's gut microbiome adjusts. Your baby may experience minor bloating, gas or intestinal gurgling which should subside with continued use. Consult your healthcare professional if symptoms continue after two weeks.

Tamper Evident: Do not use if bottle or dropper appears to be opened.

🧪 Formulation Notes

Allergy friendly Free from Milk Wheat Eggs Tree nuts Peanuts

Naturally sourced LGG Most researched strain in children Based on the number of Lactobacillus rhamnosus GG studies, as of January 2019

Guaranteed purity & potency Guaranteed potency through date on box when stored as directed.

Dairy Gluten Soy free Meets the FDA's guidelines for gluten free. Not a reduced calorie food

Probiotic + Chamomile drops

Helps reduce fussiness and crying Due to occasional digestive upset. Reduces occasional digestive upset

Probiotic Supplement with Chamomile

0-12 months

Culturelle Baby Calm + Comfort helps you soothe your baby & helps their digestive system work better. This product contains safe & gentle ingredients that work naturally with your baby's body to help reduce fussiness & crying & helps keep your baby's gut microbiome balanced & healthy.

Additional Information

The Culturelle Difference Excludes gummy formulas. #1 Pediatrician recommended brand Based on a 2018 survey among pediatricians recommending a probiotic brand.

Yellow color and creamy consistency are normal.

Storage Instructions: Store Culturelle in a cool, dry place away from direct sunlight.

Product Details

UPC / SKU 0 49100 40052 5
DSLD Entry Date 2021-04-22
Product Type Other Combinations
Form Liquid
DSLD ID 246009
Data Updated 2026-04-11

Research Evidence

691 Research Sources
52 Avg Quality Score
255 Clinical Trial
205 Meta Analysis
123 Rct
81 Systematic Review
18 Cochrane Review
2 Guideline
2 Regulatory Source
1 Other
1 Narrative Review
1 Openfda Safety
A Probiotics for preventing acute upper respiratory tract infections
Systematic Review The Cochrane database of systematic reviews 2022
A Probiotics for preventing acute upper respiratory tract infections
Meta Analysis The Cochrane database of systematic reviews 2015
A Probiotics for maintenance of remission in ulcerative colitis
Meta Analysis The Cochrane database of systematic reviews 2020
A Probiotics for induction of remission in ulcerative colitis
Meta Analysis The Cochrane database of systematic reviews 2020
A Probiotics for preventing acute upper respiratory tract infections
Meta Analysis The Cochrane database of systematic reviews 2011
A Probiotics for treating eczema
Meta Analysis The Cochrane database of systematic reviews 2018
A Probiotics for treating acute infectious diarrhoea
Meta Analysis The Cochrane database of systematic reviews 2020
A The Gut Microbiome in Depression and Potential Benefit of Prebiotics, Probiotics and Synbiotics: A Systematic Review of Clinical Trials and Observational Studies
Systematic Review International journal of molecular sciences 2022
A Probiotics for the prevention of Clostridium difficile-associated diarrhea in adults and children
Meta Analysis The Cochrane database of systematic reviews 2017
A Probiotics to prevent infantile colic
Meta Analysis The Cochrane database of systematic reviews 2019
View all evidence for Probiotics →

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