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Baby Calm + Comfort

product on market Liquid Culturelle Baby Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 50% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · methodology

Lactobacillus rhamnosus GG is supported by strong evidence for promoting infant digestive health. German chamomile flower extract is used for calming effects, though research evidence for this specific application is more limited. The overall evidence coverage for this ingredient profile is low.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for Baby Calm + Comfort
Open Full PDF View on NIH DSLD →
Details

Label Data

5 Drop(s)
Serving Size
30
Servings
Other Combinations
Product Type
50%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Calories
Total Carbohydrates
Market median: 80.0mg (20 products) 337 studies (A:8, B:183)
Market median: 400.0mg (142 products) 10 studies (A:0, B:2)

Other Ingredients

Rice bran oil Carnauba Wax
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Directions for 0-12 months: Shake before use. Use 5 drops once a day. Dispense onto a spoon, directly into baby's mouth, bottle or while breastfeeding. Replace cap with dropper. Once opened, use within 60 days.

Warnings & Precautions

For questions, concerns or to report an adverse event, please call (800) 722-3476 www.Culturelle.com

Please consult your healthcare professional prior to use.

Warning: Keep out of reach of children. When first taking a probiotic, your baby's gut microbiome adjusts. Your baby may experience minor bloating, gas or intestinal gurgling which should subside with continued use. Consult your healthcare professional if symptoms continue after two weeks.

Tamper Evident: Do not use if bottle or dropper appears to be opened.

Formulation Notes

Allergy friendly Free from Milk Wheat Eggs Tree nuts Peanuts

Naturally sourced LGG Most researched strain in children Based on the number of Lactobacillus rhamnosus GG studies, as of January 2019

Guaranteed purity & potency Guaranteed potency through date on box when stored as directed.

Dairy Gluten Soy free Meets the FDA's guidelines for gluten free. Not a reduced calorie food

Probiotic + Chamomile drops

Helps reduce fussiness and crying Due to occasional digestive upset. Reduces occasional digestive upset

Probiotic Supplement with Chamomile

0-12 months

Culturelle Baby Calm + Comfort helps you soothe your baby & helps their digestive system work better. This product contains safe & gentle ingredients that work naturally with your baby's body to help reduce fussiness & crying & helps keep your baby's gut microbiome balanced & healthy.

Additional Information

The Culturelle Difference Excludes gummy formulas. #1 Pediatrician recommended brand Based on a 2018 survey among pediatricians recommending a probiotic brand.

Yellow color and creamy consistency are normal.

Storage Instructions: Store Culturelle in a cool, dry place away from direct sunlight.

Metadata

Product Details

UPC / SKU0 49100 40052 5
DSLD Entry Date2021-04-22
Product TypeOther Combinations
FormLiquid
DSLD ID246009
Data Updated2026-04-11
Research

Research Evidence

691
Research Sources
52
Avg Quality
255
Clinical Trial
205
Meta Analysis
123
Rct
81
Systematic Review
18
Cochrane Review
2
Guideline
2
Regulatory Source
1
Other
1
Narrative Review
1
Openfda Safety
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A Probiotics for preventing acute upper respiratory tract infections
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A Probiotics for treating eczema
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A Probiotics for treating acute infectious diarrhoea
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A The Gut Microbiome in Depression and Potential Benefit of Prebiotics, Probiotics and Synbiotics: A Systematic Review of Clinical Trials and Observational Studies
Systematic Review International journal of molecular sciences 2022 PubMed DOI
A Probiotics for the prevention of Clostridium difficile-associated diarrhea in adults and children
Meta Analysis The Cochrane database of systematic reviews 2017 PubMed DOI
A Probiotics to prevent infantile colic
Meta Analysis The Cochrane database of systematic reviews 2019 PubMed DOI
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.