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LipidOptimal

product on market Capsule Karuna Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 62% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · methodology

This formula contains Vitamin D3 and E, which have strong evidence for supporting immune and antioxidant functions. Chromium and inositol hexanicotinate are linked to metabolic support, while oyster mushroom research is more limited. Overall, the profile utilizes a mix of well-established nutrients and emerging botanical extracts.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for LipidOptimal
Open Full PDF View on NIH DSLD →
Details

Label Data

6 Capsule(s)
Serving Size
30
Servings
Other Combinations
Product Type
62%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

1000 IU (250% DV)
1.7× RDA — within safe limits 608 studies (A:16, B:251)
200 mg (677% DV)
13.3× RDA — above typical dose (UL: 1000 mg) 179 studies (A:3, B:90)
400 mcg (334% DV)
11.4× RDA — above typical dose 199 studies (A:1, B:55)
Market median: 550.0mg (217 products) 29 studies (A:0, B:5)
Oyster mushroom
1000 mg
Pantethine
900 mg
Kudzu
100 mg
Market median: 500.0mg (497 products) 135 studies (A:0, B:40)

Other Ingredients

Gelatin Capsule Tricalcium Phosphate Vegetable Stearate
Claims

Label Claims — Verification

Unverified All Other
Info

Product Information

Directions for Use

Suggested use for adults: Six capsules daily in divided doses, or as directed by your health care practitioner. Supplementation of CoQ-10 is recommended, as oyster mushroom components may lower tissue levels of CoQ-10.

Warnings & Precautions

This product should not be combined with chemotherapy drugs.

Keep out of reach of children.

Formulation Notes

This product contains no yeast, wheat, corn, nuts, milk, salt, sugar, artificial coloring, preservatives or flavoring.

Additional Information

KARUNA(R) RESPONSIBLE NUTRITION(TM)

Advanced Approach to Superior Long-Term Cardiovascular Health

This product is intended for professional use and is manufactured under strict quality control to ensure the optimum in purity, potency and reliability.

Keep in a cool, dry place, tightly capped.

E01/13 L912022

9116-LB1

Metadata

Product Details

DSLD Entry Date2013-08-23
Product TypeOther Combinations
FormCapsule
BrandKaruna
DSLD ID24500
Data Updated2026-04-11
Research

Research Evidence

872
Research Sources
53
Avg Quality
309
Meta Analysis
309
Clinical Trial
111
Rct
71
Systematic Review
55
Guideline
4
Cochrane Review
4
Regulatory Source
2
Other
2
Narrative Review
2
Observational
1
Openfda Safety
A Vitamin D and vitamin D analogues for preventing fractures associated with involutional and post-menopausal osteoporosis
Meta Analysis The Cochrane database of systematic reviews 2009 PubMed DOI
A Vitamin D supplementation for prevention of mortality in adults
Meta Analysis The Cochrane database of systematic reviews 2014 PubMed DOI
A Vitamin D and vitamin D analogues for preventing fractures in post-menopausal women and older men
Meta Analysis The Cochrane database of systematic reviews 2014 PubMed DOI
A Vitamin D supplementation for prevention of cancer in adults
Meta Analysis The Cochrane database of systematic reviews 2014 PubMed DOI
A Interventions for preventing falls in older people in care facilities and hospitals
Meta Analysis The Cochrane database of systematic reviews 2018 PubMed DOI
A Drugs for preventing lung cancer in healthy people
Meta Analysis The Cochrane database of systematic reviews 2020 PubMed DOI
A Vitamin D supplementation for prevention of mortality in adults
Meta Analysis The Cochrane database of systematic reviews 2011 PubMed DOI
A High prevalence of vitamin D deficiency in Asia: A systematic review and meta-analysis
Meta Analysis Critical reviews in food science and nutrition 2023 PubMed DOI
A The effect of vitamin D supplementation on depressive symptoms in adults: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Critical reviews in food science and nutrition 2023 PubMed DOI
A Interventions for preventing falls in older people living in the community
Meta Analysis The Cochrane database of systematic reviews 2009 PubMed DOI
View all evidence for Vitamin D →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.