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Adreno Distress Guard

product on market Softgel Capsule Perque Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 30% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · methodology

Rhodiola and Relora are supported by moderate evidence for reducing stress and fatigue. Perilla oil and phospholipids provide essential fatty acids, though clinical evidence for their specific role in adrenal support is limited. The ingredient profile maintains a high safety rating.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for Adreno Distress Guard
Open Full PDF View on NIH DSLD →
Details

Label Data

2 Softgel(s)
Serving Size
30
Servings
Other Combinations
Product Type
30%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

300 mg
Market median: 300.0mg (122 products) 22 studies (A:0, B:7)
Relora
500 mg
Perilla Oil
800 mg
Medium Chain Triglycerides
250 mg
Within RDA (0.2× RDA) 38 studies (A:1, B:7)
Beeswax
70 mg
Gelatin
500 mg
Water
20 mg
Market median: 450.0mg (254 products) 243 studies (A:0, B:100)
Glycerin
12 mg

Other Ingredients

None
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Directions: As a dietary supplement, take two (2) softgels daily or as directed by your health professional.

Warnings & Precautions

Keep out of reach of children.

Do not use product if the tamper-resistant shrink band around the cap or the inner seal beneath the cap appears to have been tampered with or is missing.

Warning: Pregnant and nursing mothers need to check with their health professional before taking supplements.

Formulation Notes

Does not contain: Citrus, MSG, wheat, gluten, corn, starch, sugar, soy, yeast, zein, sulfates, phosphates (other than coenzymes), preservatives, casein or other milk derivatives. No GMO's; No toxic minerals or metals

Micellized softgel

Enables stress hormone balance

With Relora

Full disclosure label (no hidden or inactive ingredients)

Additional Information

Must be stored with cap on tightly in a cool, dry place.

Uniquely Perque 100% active 100% natural 100% verified

Store below 70 degrees F.

Metadata

Product Details

DSLD Entry Date2021-01-22
Product TypeOther Combinations
FormSoftgel Capsule
BrandPerque
DSLD ID240634
Data Updated2026-04-11
Research

Research Evidence

39
Research Sources
51
Avg Quality
16
Rct
14
Systematic Review
5
Clinical Trial
4
Meta Analysis
B The efficacy and safety of Chinese herbal medicine, Rhodiola formulation in treating ischemic heart disease: a systematic review and meta-analysis of randomized controlled trials
Meta Analysis Complementary therapies in medicine 2014 PubMed DOI
B Clinical evidence for the adaptogenic effects of Withania somnifera and Rhodiola rosea - A systematic review with molecular interpretation of psychometric outcomes
Systematic Review Annals of agricultural and environmental medicine : AAEM 2026 PubMed DOI
B Efficacy and safety of Rhodiola crenulata extract in the treatment of acute high altitude disease, based on studies involving populations in China: A systematic review and meta-analysis
Systematic Review Frontiers in pharmacology 2025 PubMed DOI
B The Impact of Rhodiola Rosea Extract on Strength Performance in Alternative Bench-Press and Bench-Pull Exercises Under Resting and Mental Fatigue Conditions: A Randomized, Triple-Blinded, Placebo-Controlled, Crossover Trial
Rct Nutrients 2025 PubMed DOI
B Liver function monitoring: a prospective nested case-control study of Salvia miltiorrhiza polyphenol injection
Meta Analysis Scientific reports 2020 PubMed DOI
B A combination of green tea, rhodiola, magnesium and B vitamins modulates brain activity and protects against the effects of induced social stress in healthy volunteers
Rct Nutritional neuroscience 2022 PubMed DOI
B Standardized Rhodiola rosea injection for left ventricular remodeling and inflammation in patients with HFrEF: a systematic review and meta-analysis
Systematic Review Frontiers in pharmacology 2025 PubMed DOI
C Rhodiola rosea for physical and mental fatigue: a systematic review
Systematic Review BMC complementary and alternative medicine 2012 PubMed DOI
C Dazhu Hongjingtian Preparation as Adjuvant Therapy for Unstable Angina Pectoris: A Meta-Analysis of Randomized Controlled Trials
Systematic Review Frontiers in pharmacology 2020 PubMed DOI
C Understanding the research landscape of over-the-counter herbal products, dietary supplements, and medications evaluated for depressive symptoms in adults: a scoping review
Systematic Review Frontiers in pharmacology 2025 PubMed DOI
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.