🟢 100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • Limited research evidence available for ingredients
B Label Compliance Grade

Product Label

📸

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Label Data

1 Tablet(s) Serving Size
Botanical Product Type
0% Evidence Coverage

Supplement Facts — Evidence Check

Total Carbohydrates
1 Gram(s) (1% DV)
📊 Market median: 300.0mg (240 products) 📚 11 studies — no high-quality reviews
This product: 450mg

Other Ingredients

Cellulose Sodium Croscarmellose Stearic Acid Magnesium Stearate Silica Hypromellose Glycerin Carnauba Wax

Label Claims — Verification

All Other
Structure/Function
All Other (99% of products) Structure/Function (78% of products) Nutrient (2% of products)

Target Groups

Vegan Vegetarian Adult (18 - 50 Years) Women (not pregnant or lactating) Gluten Free Dairy Free Sugar Free

Product Information

📋 Directions for Use

Recommendation: Take 1 tablet twice daily.

⚠️ Warnings & Precautions

Warning: This product should not be used by pregnant or nursing women, or by individuals who are taking antidepressant medications. Individuals taking other medications should seek the advice of a prescribing physician prior to using this product.

Avoid excessive exposure to UV radiation (e.g., sunlight or tanning) while using the product.

Keep out of reach of children.

Safety sealed with printed inner seal. Do not use if seal is broken or missing.

🧪 Formulation Notes

Promotes a positive mood

St. John's Wort has been used for centuries to help promote a positive mood. We source from the regions where it grows best, like Chile and Europe, where the soil is dry and the cooler climate makes for perfect growing conditions. At Nature's Way, we believe nature knows best. That's why our mission is to seek out the best herbs the earth has to give. It's the way we deliver uncompromising quality and help you live healthier.

Premium extract

450 mg per serving

Gluten free. No sugar, salt, yeast, wheat, soy, dairy products, or artificial colors, flavors, or preservatives.

Vegan

Additional Information

Nature's Way since 1969

Bottles made From 97% Post-consumer Recycled plastic

Quality Global Sourcing Bottled & Tested In the USA

Product Details

UPC / SKU 7 63948 08670 2
DSLD Entry Date 2020-07-23
Product Type Botanical
Form Tablet or Pill
Brand Nature's Way
DSLD ID 229843
Data Updated 2026-04-11

Research Evidence

43 Research Sources
48 Avg Quality Score
16 Meta Analysis
14 Systematic Review
7 Rct
4 Regulatory Source
1 Clinical Trial
1 Openfda Safety
B St John's wort for major depression
Systematic Review The Cochrane database of systematic reviews 2008
B Clinical use of Hypericum perforatum (St John's wort) in depression: A meta-analysis
Meta Analysis Journal of affective disorders 2017
B A systematic review of St. John's wort for major depressive disorder
Meta Analysis Systematic reviews 2016
B St John's wort for depression
Systematic Review The Cochrane database of systematic reviews 2000
B Efficacy of Pharmacological Interventions in Milder Depression: A Systematic Review and Meta-Analysis
Meta Analysis Neuropsychopharmacology reports 2025
B St John's wort for depression
Meta Analysis The Cochrane database of systematic reviews 2005
C St John's wort for depression: meta-analysis of randomised controlled trials
Meta Analysis The British journal of psychiatry : the journal of mental science 2005
C The effect of Hypericum perforatum on postmenopausal symptoms and depression: A randomized controlled trial
Rct Complementary therapies in medicine 2019
C Hypericum extract versus imipramine or placebo in patients with moderate depression: randomised multicentre study of treatment for eight weeks
Rct BMJ (Clinical research ed.) 1999
C Hypericum perforatum as a cognitive enhancer in rodents: A meta-analysis
Meta Analysis Scientific reports 2016
View all evidence for St Johns Wort →

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