Betaine HCL and Pepsin
100/100
This product looks safe
- No ingredients exceed tolerable upper intake levels
- 60% of ingredients have research evidence
A
Label Compliance Grade
What the Evidence Says
AI-generated · Qwen 3.6 · methodologyBetaine HCl and pepsin are used to support digestive enzyme activity and stomach acid levels. B vitamins, including B1, B6, and niacin, play roles in cellular energy metabolism. There is moderate research evidence supporting these ingredients for digestive support and metabolic function.
AI-generated summary based on research evidence. Not medical advice.
Label
Product Label
Details
Label Data
1 Tablet(s)
Serving Size
Other Combinations
Product Type
60%
Evidence Coverage
Ingredients
Supplement Facts — Evidence Check
5 mg
(333% DV)
4.2× RDA — above typical dose
76 studies (A:0, B:33)
15 mg
(75% DV)
1.1× RDA — within safe limits
196 studies (A:5, B:63)
1.5 mg
(75% DV)
1.2× RDA — within safe limits
114 studies (A:3, B:35)
324 mg
Market median: 496.0mg (192 products)
20 studies — no high-quality reviews
Pepsin
135 mg
Other Ingredients
Microcrystalline Cellulose
Stearic Acid
Croscarmellose Sodium
Silicon Dioxide
Magnesium Stearate
Hypromellose
Glycerin
Hydroxypropyl Cellulose
Claims
Label Claims — Verification
Unverified
All Other
Info
Product Information
Directions for Use
Suggested use: One tablet daily, or as directed by a physician.
Warnings & Precautions
Notice: It is advisable to keep this and all supplements out of the reach of children.
Additional Information
Am noon pm
Metadata
Product Details
DSLD Entry Date2020-06-24
Product TypeOther Combinations
FormTablet or Pill
DSLD ID229108
Data Updated2026-04-11
Research
Research Evidence
23
Research Sources
47
Avg Quality
18
Rct
3
Systematic Review
1
Meta Analysis
1
Clinical Trial
B
Effect of Folic Acid, Betaine, Vitamin B₆, and Vitamin B12 on Homocysteine and Dimethylglycine Levels in Middle-Aged Men Drinking White Wine
C
Betaine for nonalcoholic fatty liver disease: results of a randomized placebo-controlled trial
C
Guidelines for the diagnosis and management of cystathionine beta-synthase deficiency
C
Newborn screening for homocystinurias and methylation disorders: systematic review and proposed guidelines
C
Effects of low-dose B vitamins plus betaine supplementation on lowering homocysteine concentrations among Chinese adults with hyperhomocysteinemia: a randomized, double-blind, controlled preliminary clinical trial
C
Association of Betaine-Homocysteine S-Methyl Transferase (rs3797546 and rs3733890) polymorphisms with non-syndromic cleft lip/palate: A meta-analysis
C
Two methods for assessment of choline status in a randomized crossover study with varying dietary choline intake in people: isotope dilution MS of plasma and in vivo single-voxel magnetic resonance spectroscopy of liver.
C
Effect of inulin supplementation on fecal and blood metabolome in alcohol use disorder patients: A randomised, controlled dietary intervention.
C
Choline and betaine concentrations in plasma discriminate levels of dietary choline intake in healthy adults: analysis of a double-blind randomized crossover controlled feeding study.
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.