🟢 100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 50% of ingredients have research evidence
A Label Compliance Grade

Product Label

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Label Data

1 Tablet(s) Serving Size
Botanical with Nutrients Product Type
50% Evidence Coverage

Supplement Facts — Evidence Check

100 mg
📊 Market median: 100.0mg (116 products) 📚 15 studies (Tier A: 0, B: 3)
This product: 100mg
Provided by 102.05mg Griffonia
102.05 mg

Other Ingredients

Dicalcium Phosphate Microcrystalline Cellulose Silicon Dioxide Magnesium Stearate

Label Claims — Verification

All Other
All Other (99% of products) Structure/Function (78% of products) Nutrient (52% of products)

Target Groups

Vegetarian Adult (18 - 50 Years)

Product Information

📋 Directions for Use

Suggested Daily Intake Take one tablet one hour before bedtime as a food supplement or as directed by a healthcare professional.

⚠️ Warnings & Precautions

Important Information If you are taking any prescription medication, you have a medical condition or you have specific concerns about the suitability of our products, always consult your GP or Pharmacist prior to taking supplements.

Do not exceed stated dose.

Keep away from children at all times.

Do not use if seal is broken.

Pregnant or lactating women should consult a Doctor before using this product.

Food supplement: This product should not be used as a substitute for a varied diet.

🧪 Formulation Notes

Suitable for vegetarians.

Additional Information

SimplySupplements(TM)

SUPER STRENGTH

V

QUALITY ASSURED

AutoDespatch SAVE 10% and get FREE P&P on all repeat orders by having your favourite supplements conveniently scheduled and delivered automatically with our unique AutoDespatch system. Same Day Despatch We will ensure your order is despatched on the day of receipt (when placed before 12.30pm) and that all orders placed after 12.30pm are despatched on the next working day. All sent 1st class! PriceMatch Guarantee! If you buy from us and then see the same product cheaper elsewhere we will refund the difference plus 10%!

Natural amino acid involved in the production of serotonin

Product Information 5-Hydroxytryptophan is used by the body to produce serotonin. Serotonin is involved in mood, appetite and impulse control. The level of serotonin in the brain has an effect on our state of restfulness and restlessness.

Store in a cool dry place.

S480

Image is for illustration purposes only.

Product Details

UPC / SKU 5 060208 418040
DSLD Entry Date 2013-07-25
Product Type Botanical with Nutrients
Form Tablet or Pill
DSLD ID 22359
Data Updated 2026-04-11

Research Evidence

21 Research Sources
53 Avg Quality Score
11 Systematic Review
6 Rct
4 Meta Analysis
B Combination pharmacotherapy for the treatment of fibromyalgia in adults
Systematic Review The Cochrane database of systematic reviews 2018
B Tryptophan and 5-hydroxytryptophan for depression
Systematic Review The Cochrane database of systematic reviews 2001
B Tryptophan and 5-hydroxytryptophan for depression
Systematic Review The Cochrane database of systematic reviews 2002
B The impact of 5-hydroxytryptophan supplementation on sleep quality and gut microbiota composition in older adults: A randomized controlled trial
Rct Clinical nutrition (Edinburgh, Scotland) 2024
B The Impact of 5-Hydroxytryptophan Supplementation on Cognitive Function and Mood in Singapore Older Adults: A Randomized Controlled Trial
Rct Nutrients 2025
B The Efficacy of Different Triptans for the Treatment of Acute Headache in Pediatric Migraine: A Systematic Review
Systematic Review Indian pediatrics 2023
B The effect of therapeutic massage combined with conventional therapy in children with functional dyspepsia: a systematic review and meta-analysis
Systematic Review Frontiers in pharmacology 2025
C Sleep disorders in children
Systematic Review BMJ clinical evidence 2010
C Effects of 5-hydroxytryptophan on distinct types of depression: a systematic review and meta-analysis
Meta Analysis Nutrition reviews 2020
C Investigating genetic links between biological aging and adverse pregnancy outcomes
Meta Analysis Biogerontology 2025
View all evidence for 5 Htp →

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