Home/ Supplements/ Nicotinamide Riboside/ Nicotinamide Riboside Chloride 125 mg

Nicotinamide Riboside Chloride 125 mg

product on market Capsule SuperSmart Safety: 60/100
60/100

Review before taking

  • Nicotinamide Riboside Chloride: 250mg is 7.1× the Tolerable Upper Intake Level (35mg)
  • 100% of ingredients have research evidence
C Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · grounded in 1 source · methodology

Nicotinamide Riboside Chloride is used to increase NAD+ levels, though clinical evidence for its efficacy in humans remains limited. Due to a safety score of 60, users should be aware of potential adverse effects. Consult a professional regarding suitability.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Nicotinamide Riboside Chloride: 250mg is 7.1× the Tolerable Upper Intake Level (35mg)

✨ AI-generated · Qwen 3.6 · grounded in 2 sources · methodology

This product received a low safety score because the amount of Nicotinamide Riboside Chloride exceeds the recommended upper intake limit. Specifically, the dosage is over seven times higher than the established safety threshold.

Label

Product Label

Label for Nicotinamide Riboside Chloride 125 mg
Open Full PDF View on NIH DSLD →
Details

Label Data

2 Capsule(s)
Serving Size
30
Servings
Vitamin
Product Type
100%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Exceeds UL by 7.1× (UL: 35 mg) 196 studies (A:5, B:63)

Other Ingredients

Rice Bran Magnesium Stearate
Claims

Label Claims — Verification

Unverified All Other
Info

Product Information

Directions for Use

Recommended use: Adults. Take 2 capsule a day.

Warnings & Precautions

Precautions: Do not exceed the recommended daily dose. This product is a nutritional supplement and should not replace a varied, balanced diet.

Keep out of childrens' reach.

As with any nutritional supplement, you should consult a health professional before taking this product if you are pregnant, breastfeeding or have a health problem.

Formulation Notes

Each capsule contains 125 mg of nicotinamide riboside chloride.

Additional Information

Store away from direct light, heat and humidity.

Metadata

Product Details

DSLD Entry Date2020-06-24
Product TypeVitamin
FormCapsule
BrandSuperSmart
DSLD ID222934
Data Updated2026-04-11
Research

Research Evidence

10
Research Sources
49
Avg Quality
8
Rct
1
Systematic Review
1
Clinical Trial
B Chronic nicotinamide riboside supplementation is well-tolerated and elevates NAD+ in healthy middle-aged and older adults
Rct Nature communications 2018 PubMed DOI
C The effects of NAD+ precursor (nicotinic acid and nicotinamide) supplementation on weight loss and related hormones: a systematic review and meta-regression analysis of randomized controlled trials
Systematic Review Frontiers in nutrition 2023 PubMed DOI
C Effect of nicotinamide riboside on airway inflammation in COPD: a randomized, placebo-controlled trial.
Rct Nature aging PubMed DOI
C Safety and Metabolism of Long-term Administration of NIAGEN (Nicotinamide Riboside Chloride) in a Randomized, Double-Blind, Placebo-controlled Clinical Trial of Healthy Overweight Adults
Rct Scientific reports 2019 PubMed DOI
C Nicotinamide Riboside Augments the Aged Human Skeletal Muscle NAD+ Metabolome and Induces Transcriptomic and Anti-inflammatory Signatures
Rct Cell reports 2019 PubMed DOI
C Oral nicotinamide riboside raises NAD+ and lowers biomarkers of neurodegenerative pathology in plasma extracellular vesicles enriched for neuronal origin
Rct Aging cell 2023 PubMed DOI
C Nicotinamide riboside with pterostilbene (NRPT) increases NAD+ in patients with acute kidney injury (AKI): a randomized, double-blind, placebo-controlled, stepwise safety study of escalating doses of NRPT in patients with AKI
Rct BMC nephrology 2020 PubMed DOI
C Clinical Trial of Niagen to Examine Recovery in People With Persistent Cognitive and Physical Symptoms After COVID-19
Clinical Trial ClinicalTrials.gov 2021
C A randomized placebo-controlled trial of nicotinamide riboside and pterostilbene supplementation in experimental muscle injury in elderly individuals.
Rct JCI insight PubMed DOI
C Nicotinamide Riboside Supplementation Benefits in Patients With Werner Syndrome: A Double-Blind Randomized Crossover Placebo-Controlled Trial.
Rct Aging cell PubMed DOI
View all evidence for Nicotinamide Riboside →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.