Pure Niacinamide 250 mg by Freeda — Ingredients, Evidence & Safety

Product Label

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Safety Alerts

⚠️ Niacin: 250mg is 7.1× the Tolerable Upper Intake Level (35mg)

This product received a low safety score because the amount of niacin in a single dose is over seven times higher than the recommended maximum daily limit of 35mg.

Label Data

1 Vegetarian Capsule(s) Serving Size

Vitamin Product Type

100% Evidence Coverage

Supplement Facts — Evidence Check

Niacin

250 mg NE (1563% DV)

⚠️ Exceeds Tolerable Upper Intake Level by 7.1× (UL: 35 mg) 📚 193 studies (Tier A: 5, B: 63)

RDA 14mg This product: 250mg UL 35mg

Other Ingredients

Vegetable Cellulose Capsule Cellulose Vegetarian Stearate Silica

Label Claims — Verification

❓ All Other

All Other (97% of products) Structure/Function (86% of products) Nutrient (36% of products)

Target Groups

Vegan Vegetarian Adult (18 - 50 Years) Kosher Gluten Free Sugar Free

Product Information

📋 Directions for Use

Suggested Use: Adults, take one (1) capsule daily preferably with food and liquid.

⚠️ Warnings & Precautions

Keep out of the reach of children

🧪 Formulation Notes

No gluten No lactose No artificial colors No artificial flavors No animal derivatives No sugar or starch No gelatin No yeast

Vegan

NSKC (New Square Rabbinical Kashrus Council) OU Pareve (Kosher)

Additional Information

Store product at room temperature. Do not expose to excessive heat or moisture.

Manufactured in a GMP certified facility in the USA

Freeda since 1928 Now in capsules

NSKC (New Square Rabbinical Kashrus Council) OU Pareve (Kosher)

Product Details

UPC / SKU 7 58487 03223 5

DSLD Entry Date 2020-05-22

Product Type Vitamin

Form Capsule

Brand Freeda

DSLD ID 221468

Data Updated 2026-04-11

Research Evidence

241 Research Sources

55 Avg Quality Score

113 Meta Analysis

75 Systematic Review

32 Rct

11 Clinical Trial

3 Other

3 Regulatory Source

1 Cochrane Review

1 Narrative Review

1 Openfda Safety

A Niacin for primary and secondary prevention of cardiovascular events

Meta Analysis The Cochrane database of systematic reviews 2017

PubMed DOI Cochrane

A Use of high potency statins and rates of admission for acute kidney injury: multicenter, retrospective observational analysis of administrative databases

Meta Analysis BMJ (Clinical research ed.) 2013

PubMed DOI

A Effect on cardiovascular risk of high density lipoprotein targeted drug treatments niacin, fibrates, and CETP inhibitors: meta-analysis of randomised controlled trials including 117,411 patients

Meta Analysis BMJ (Clinical research ed.) 2014

PubMed DOI

A A terminal metabolite of niacin promotes vascular inflammation and contributes to cardiovascular disease risk

Meta Analysis Nature medicine 2024

PubMed DOI

A Meta-analysis and imputation refines the association of 15q25 with smoking quantity

Meta Analysis Nature genetics 2010

PubMed DOI

A Genome-wide meta-analyses identify multiple loci associated with smoking behavior

Meta Analysis Nature genetics 2010

PubMed DOI

A Antidepressants for smoking cessation

Meta Analysis The Cochrane database of systematic reviews 2014

PubMed DOI

A Topical azelaic acid, salicylic acid, nicotinamide, sulphur, zinc and fruit acid (alpha-hydroxy acid) for acne

Meta Analysis The Cochrane database of systematic reviews 2020

PubMed DOI Cochrane

B Assessment of the Role of Niacin in Managing Cardiovascular Disease Outcomes: A Systematic Review and Meta-analysis

Meta Analysis JAMA network open 2019

PubMed DOI

B Association Between Lowering LDL-C and Cardiovascular Risk Reduction Among Different Therapeutic Interventions: A Systematic Review and Meta-analysis

Meta Analysis JAMA 2016

PubMed DOI

View all evidence for Niacin →