Home/ Supplements/ 5 Htp/ Neuro-5-HTP Plus

Neuro-5-HTP Plus

product on market Capsule Biotics Research Corporation Safety: 94/100
94/100

This product looks safe

  • Niacin: 50mg is 1.4× the Tolerable Upper Intake Level (35mg)
  • 67% of ingredients have research evidence
C Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · methodology

L-5-HTP and L-Theanine are supported by moderate evidence for promoting relaxation and mood regulation. Niacin and Vitamin B6 serve as essential cofactors for neurotransmitter synthesis, while Superoxide Dismutase provides antioxidant support. Overall, these ingredients are generally well-tolerated with a high safety profile.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Niacin: 50mg is 1.4× the Tolerable Upper Intake Level (35mg)

Label

Product Label

Label for Neuro-5-HTP Plus
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Capsule(s)
Serving Size
Other Combinations
Product Type
67%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

50 mg (250% DV)
Exceeds UL by 1.4× (UL: 35 mg) 196 studies (A:5, B:63)
10 mg (500% DV)
7.7× RDA — above typical dose (UL: 100 mg) 114 studies (A:3, B:35)
Market median: 100.0mg (116 products) 18 studies (A:0, B:3)
50 mg
Market median: 200.0mg (358 products) 9 studies (A:0, B:2)
Superoxide Dismutase
50 mcg
Catalase
50 mcg

Other Ingredients

Gelatin Water Glycerin
Claims

Label Claims — Verification

Unverified All Other
Info

Product Information

Directions for Use

RECOMMENDATION: One (1) capsule taken two (2) times each day as a dietary supplement or as otherwise directed by a healthcare professional.

Warnings & Precautions

Caution: Not recommended for pregnant or lactating women.

KEEP OUT OF REACH OF CHILDREN

Sealed with an imprinted safety seal for your protection.

Additional Information

Store in a cool, dry area.

Rev. 8/08

Specially grown, biologically active containing naturally associated and/or organically bound phytochemicals including polyphenolic compounds with SOD and catalase, dehydrated at low temperature to preserve associated enzyme factors.

Metadata

Product Details

DSLD Entry Date2013-06-25
Product TypeOther Combinations
FormCapsule
DSLD ID22112
Data Updated2026-04-11
Research

Research Evidence

21
Research Sources
53
Avg Quality
11
Systematic Review
6
Rct
4
Meta Analysis
B Combination pharmacotherapy for the treatment of fibromyalgia in adults
Systematic Review The Cochrane database of systematic reviews 2018 PubMed DOI
B Tryptophan and 5-hydroxytryptophan for depression
Systematic Review The Cochrane database of systematic reviews 2001 PubMed
B Tryptophan and 5-hydroxytryptophan for depression
Systematic Review The Cochrane database of systematic reviews 2002 PubMed
B The impact of 5-hydroxytryptophan supplementation on sleep quality and gut microbiota composition in older adults: A randomized controlled trial
Rct Clinical nutrition (Edinburgh, Scotland) 2024 PubMed DOI
B The Impact of 5-Hydroxytryptophan Supplementation on Cognitive Function and Mood in Singapore Older Adults: A Randomized Controlled Trial
Rct Nutrients 2025 PubMed DOI
B The Efficacy of Different Triptans for the Treatment of Acute Headache in Pediatric Migraine: A Systematic Review
Systematic Review Indian pediatrics 2023 PubMed
B The effect of therapeutic massage combined with conventional therapy in children with functional dyspepsia: a systematic review and meta-analysis
Systematic Review Frontiers in pharmacology 2025 PubMed DOI
C Sleep disorders in children
Systematic Review BMJ clinical evidence 2010 PubMed
C Effects of 5-hydroxytryptophan on distinct types of depression: a systematic review and meta-analysis
Meta Analysis Nutrition reviews 2020 PubMed DOI
C Investigating genetic links between biological aging and adverse pregnancy outcomes
Meta Analysis Biogerontology 2025 PubMed DOI
View all evidence for 5 Htp →
Compare

Similar Products

View all 5 Htp products →

This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.