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Brain Defense

product on market Capsule Natural Factors 3 Brains Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 80% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · methodology

This profile includes Bacopa and Ashwagandha, which have moderate evidence for supporting cognitive function and stress response. Curcumin and Boswellia are researched for their anti-inflammatory properties, while Chamomile is used for relaxation. Overall, the evidence coverage for this specific combination is limited.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for Brain Defense
Open Full PDF View on NIH DSLD →
Details

Label Data

3 Capsule(s)
Serving Size
30
Servings
Botanical
Product Type
80%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Market median: 375.0mg (171 products) 31 studies (A:1, B:14)
Market median: 400.0mg (142 products) 10 studies (A:0, B:2)
Bacopa extract
300 mg
Market median: 450.0mg (254 products) 243 studies (A:0, B:100)
Market median: 450.0mg (502 products) 28 studies (A:0, B:8)

Other Ingredients

Vegetarian Capsule Microcrystalline Cellulose Magnesium Stearate Silica
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Suggested usage: 3 capsules per day or as directed by a health professional.

Warnings & Precautions

Cautions: As with any supplement, consult your health professional before use if you are pregnant, breastfeeding or trying to conceive, or if you are taking medication, have a medical condition, or anticipate a surgery.

Keep out of the reach of children.

Sealed for your protection. Do not use if seal is broken.

Formulation Notes

Three Brains is a line of supplements designed to support the critical relationship between our head, heart, and gut. Together, these three "brains" influence our cognition and support a healthy mind. Brain Defense supports memory, cognition, brain function, and cardiovascular health by supporting healthy cortisol and C-reactive protein levels already within the normal range. These are the biomarkers of physical stress and signs of everyday stress such as fatigue, occasional sleeplessness, irritability, mild memory loss, and temporary difficulties concentrating. It also supports an acute inflammatory response for a healthy head, heart, and gut. Manufactured by natural Factors to ensure safety and potency in accordance with Good Manufacturing Practices (GMP) of the FDA and Health Canada.

Contains no artificial colors, preservatives, or sweeteners; no dairy, starch, sugar, wheat, gluten, yeast, soy, egg, fish, shellfish, animal products, salt, tree nuts, or GMOs.

Suitable for vegetarians/vegans.

Supports memory and overall brain function through healthy inflammatory responses

Additional Information

isura Non-GMO - Mass Spec Documentation Lab tested

For freshness, store in a cool, dry place.

Recyclable container and label. Product of Canada

Purity & Potency Guaranteed

Metadata

Product Details

UPC / SKU0 68958 03060 9
DSLD Entry Date2020-05-22
Product TypeBotanical
FormCapsule
DSLD ID220815
Data Updated2026-04-11
Research

Research Evidence

33
Research Sources
55
Avg Quality
17
Systematic Review
12
Meta Analysis
3
Rct
1
Clinical Trial
A Oral herbal therapies for treating osteoarthritis
Meta Analysis The Cochrane database of systematic reviews 2014 PubMed DOI
B Interventions for treating collagenous colitis
Meta Analysis The Cochrane database of systematic reviews 2017 PubMed DOI
B Efficacy of curcumin and Boswellia for knee osteoarthritis: Systematic review and meta-analysis
Meta Analysis Seminars in arthritis and rheumatism 2018 PubMed DOI
B Evaluating the efficacy and safety of Curcuma longa, Boswellia serrata, and their mixed formulation in treating knee osteoarthritis: A systematic review and network meta-analysis
Systematic Review Complementary therapies in medicine 2026 PubMed DOI
B Effectiveness of Boswellia and Boswellia extract for osteoarthritis patients: a systematic review and meta-analysis
Meta Analysis BMC complementary medicine and therapies 2020 PubMed DOI
B Effectiveness and Safety of Ayurvedic Medicines in Type 2 Diabetes Mellitus Management: A Systematic Review and Meta-Analysis
Systematic Review Frontiers in pharmacology 2022 PubMed DOI
B Interventions for treating collagenous colitis
Meta Analysis The Cochrane database of systematic reviews 2008 PubMed DOI
B Ayurvedic interventions for osteoarthritis: a systematic review and meta-analysis
Meta Analysis Rheumatology international 2015 PubMed DOI
B Oral herbal medicines marketed in Brazil for the treatment of osteoarthritis: A systematic review and meta-analysis
Meta Analysis Phytotherapy research : PTR 2017 PubMed DOI
B Frankincense: systematic review
Systematic Review BMJ (Clinical research ed.) 2008 PubMed DOI
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.