Home/ Supplements/ Niacin/ No Flush Niacin 500 mg

No Flush Niacin 500 mg

product on market Capsule Natural Factors Safety: 80/100
80/100

This product is generally safe

  • Niacin: 500mg is 14.3× the Tolerable Upper Intake Level (35mg)
  • 100% of ingredients have research evidence
C Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · grounded in 1 source · methodology

Niacin is supported by strong evidence for managing lipid levels and cardiovascular health, while inositol has moderate evidence for supporting insulin sensitivity. Together, these ingredients aim to support metabolic function. The current evidence coverage for this specific formulation is limited.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Niacin: 500mg is 14.3× the Tolerable Upper Intake Level (35mg)

Label

Product Label

Label for No Flush Niacin 500 mg
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Capsule(s)
Serving Size
Other Combinations
Product Type
100%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

500 mg (3125% DV)
Exceeds UL by 14.3× (UL: 35 mg) 196 studies (A:5, B:63)
120 mg
Market median: 550.0mg (217 products) 29 studies (A:0, B:5)

Other Ingredients

Microcrystalline Cellulose Gelatin Capsule Magnesium Stearate
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Suggested Usage: 1 capsule 1-3 times per day or as directed by a health professional.

Warnings & Precautions

Cautions: As with any supplement, consult your health professional before use if you are pregnant, breastfeeding, or trying to conceive, or if you are taking medication, have a medical condition, or anticipate a surgery.

Keep out of the reach of children.

Sealed for your protection. Do not use if seal is broken.

Formulation Notes

No Flush Niacin contains inositol hexaniacinate, a form of niacin (vitamin B3) used in Europe for over 40 years. Inositol hexaniacinate is not associated with the side effects of other forms of niacin in high doses, such as flushing of the skin and upset stomach.

Manufactured by Natural Factors to ensure safety and potency in accordance with Good Manufacturing Practices (GMP) of the FDA and Health Canada.

Contains no artificial colors, preservatives, or sweeteners; no dairy, starch, sugar, wheat, gluten, yeast, soy, corn, egg, fish, shellfish, salt, tree nuts, or GMOs.

Inositol hexaniacinate

Additional Information

isura Non-GMO - Mass Spec Documentation Lab tested

For freshness, store in a cool, dry place.

Product of Canada Recyclable container and label.

Purity & Potency Guaranteed

Metadata

Product Details

UPC / SKU0 68958 01223 0
DSLD Entry Date2020-05-22
Product TypeOther Combinations
FormCapsule
BrandNatural Factors
DSLD ID220656
Data Updated2026-04-11
Research

Research Evidence

241
Research Sources
55
Avg Quality
113
Meta Analysis
75
Systematic Review
32
Rct
11
Clinical Trial
3
Other
3
Regulatory Source
1
Cochrane Review
1
Narrative Review
1
Openfda Safety
A Niacin for primary and secondary prevention of cardiovascular events
Meta Analysis The Cochrane database of systematic reviews 2017 PubMed DOI
A Use of high potency statins and rates of admission for acute kidney injury: multicenter, retrospective observational analysis of administrative databases
Meta Analysis BMJ (Clinical research ed.) 2013 PubMed DOI
A Effect on cardiovascular risk of high density lipoprotein targeted drug treatments niacin, fibrates, and CETP inhibitors: meta-analysis of randomised controlled trials including 117,411 patients
Meta Analysis BMJ (Clinical research ed.) 2014 PubMed DOI
A A terminal metabolite of niacin promotes vascular inflammation and contributes to cardiovascular disease risk
Meta Analysis Nature medicine 2024 PubMed DOI
A Meta-analysis and imputation refines the association of 15q25 with smoking quantity
Meta Analysis Nature genetics 2010 PubMed DOI
A Genome-wide meta-analyses identify multiple loci associated with smoking behavior
Meta Analysis Nature genetics 2010 PubMed DOI
A Antidepressants for smoking cessation
Meta Analysis The Cochrane database of systematic reviews 2014 PubMed DOI
A Topical azelaic acid, salicylic acid, nicotinamide, sulphur, zinc and fruit acid (alpha-hydroxy acid) for acne
Meta Analysis The Cochrane database of systematic reviews 2020 PubMed DOI
B Assessment of the Role of Niacin in Managing Cardiovascular Disease Outcomes: A Systematic Review and Meta-analysis
Meta Analysis JAMA network open 2019 PubMed DOI
B Association Between Lowering LDL-C and Cardiovascular Risk Reduction Among Different Therapeutic Interventions: A Systematic Review and Meta-analysis
Meta Analysis JAMA 2016 PubMed DOI
View all evidence for Niacin →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.