TMI Thyroid Metabolism + Iodine by Systemic Formulas Bio Nutriment — Ingredients, Evidence & Safety

🟡 70/100

Review before taking

Selenomethionine: 1mg is 2.5× the Tolerable Upper Intake Level (0.4mg)
Iodine: 5mg is 4.5× the Tolerable Upper Intake Level (1.1mg)
Iodide: 7.5mg is 6.8× the Tolerable Upper Intake Level (1.1mg)
Contains proprietary blend — exact ingredient amounts not disclosed
83% of ingredients have research evidence

F Label Compliance Grade

Product Label

📄 Open Full PDF View on NIH DSLD →

📸

Have a supplement label? Find it here.

Upload a photo of any supplement label to search our database of 92,312 products.

Safety Alerts

⚠️ Selenomethionine: 1mg is 2.5× the Tolerable Upper Intake Level (0.4mg)

⚠️ Iodine: 5mg is 4.5× the Tolerable Upper Intake Level (1.1mg)

⚠️ Iodide: 7.5mg is 6.8× the Tolerable Upper Intake Level (1.1mg)

ℹ️ Contains proprietary blend — exact ingredient amounts not disclosed

This product contains levels of selenium, iodine, and iodide that significantly exceed the recommended maximum daily limits. It also uses a proprietary blend, meaning the exact amounts of some ingredients are not disclosed.

Label Data

1 Capsule(s) Serving Size

Other Combinations Product Type

83% Evidence Coverage

Supplement Facts — Evidence Check

Selenomethionine

1 mg (56% DV)

⚠️ Exceeds Tolerable Upper Intake Level by 2.5× (UL: 0.4 mg) 📚 172 studies (Tier A: 0, B: 67)

RDA 0.055mg This product: 1mg UL 0.4mg

Iodine

5 mg

⚠️ Exceeds Tolerable Upper Intake Level by 4.5× (UL: 1.1 mg) 📚 243 studies (Tier A: 4, B: 133)

RDA 0.15mg This product: 5mg UL 1.1mg

Iodide

7.5 mg (8333% DV)

⚠️ Exceeds Tolerable Upper Intake Level by 6.8× (UL: 1.1 mg) 📚 243 studies (Tier A: 4, B: 133)

RDA 0.15mg This product: 7.5mg UL 1.1mg

Vitamin B6

10 mg (500% DV)

📊 7.7× RDA — above typical dose (UL: 100 mg) 📚 113 studies (Tier A: 3, B: 35)

RDA 1.3mg This product: 10mg UL 100mg

Zinc Gluconate

10 mg (14% DV)

✅ Within RDA (0.9× RDA of 11 mg) 📚 258 studies (Tier A: 6, B: 134)

RDA 11mg This product: 10mg UL 40mg

Proprietary Blend

409 mg

Other Ingredients

Gelatin Leucine

Label Claims — Verification

❓ All Other

❓ Structure/Function

All Other (98% of products) Structure/Function (74% of products) Nutrient (53% of products)

Target Groups

Adult (18 - 50 Years)

Product Information

📋 Directions for Use

DIRECTIONS FOR NUTRITIONAL USE: 1 capsule daily with food or as directed. Best when used in conjunction with #31 Ga and #39 Gf. Increase the amount of liquids you drink while taking this product.

⚠️ Warnings & Precautions

Keep away from Heat, Sunlight and Children.

Additional Information

Keep away from Heat, Sunlight and Children.

#187 K/12

Thyroid cellular metabolism (TMI) nourishes thyroid tissue and provides the ideal ratio of Iodide to Iodine needed for proper thyroid function. TMI supports proper thyroid hormone balance using a combination of essential nutrients and herbs.

SOLD THROUGH PROFESSIONALS

MADE IN U.S.A.

Product Details

UPC / SKU 6 35585 01871 5

DSLD Entry Date 2013-05-24

Product Type Other Combinations

Form Capsule

Brand Systemic Formulas Bio Nutriment

DSLD ID 22054

Data Updated 2026-04-11

Research Evidence

292 Research Sources

57 Avg Quality Score

160 Meta Analysis

70 Systematic Review

36 Rct

8 Cochrane Review

8 Clinical Trial

3 Regulatory Source

2 Narrative Review

2 Other

1 Guideline

1 Openfda Safety

A Umbilical cord antiseptics for preventing sepsis and death among newborns

Meta Analysis The Cochrane database of systematic reviews 2026

PubMed DOI

A Food fortification with multiple micronutrients: impact on health outcomes in general population

Meta Analysis The Cochrane database of systematic reviews 2019

PubMed DOI

A Interventions for cutaneous molluscum contagiosum

Meta Analysis The Cochrane database of systematic reviews 2017

PubMed DOI

A Chlorhexidine vs Povidone-Iodine and Incidence of Catheter-Related Infections: A Systematic Review and Meta-Analysis

Meta Analysis JAMA network open 2026

PubMed DOI

B Radioiodine Remnant Ablation for Differentiated Thyroid Cancer: A Systematic Review and Meta-analysis

Meta Analysis JAMA otolaryngology-- head & neck surgery 2021

PubMed DOI

B Risk of primary breast cancer in patients with differentiated thyroid cancer undergoing radioactive iodine therapy: a systematic review and meta-analysis

Meta Analysis European journal of nuclear medicine and molecular imaging 2022

PubMed DOI

B Alcoholic chlorhexidine skin preparation or triclosan-coated sutures to reduce surgical site infection: a systematic review and meta-analysis of high-quality randomised controlled trials

Meta Analysis The Lancet. Infectious diseases 2022

PubMed DOI

B Oral hygiene care for critically ill patients to prevent ventilator-associated pneumonia

Meta Analysis The Cochrane database of systematic reviews 2013

PubMed DOI

B Interventions for ingrowing toenails

Meta Analysis The Cochrane database of systematic reviews 2012

PubMed DOI

B Interventions for the management of malignant pleural effusions: a network meta-analysis

Systematic Review The Cochrane database of systematic reviews 2016

PubMed DOI

View all evidence for Iodine →