RegeneRest

product on market Capsule Clinical Synergy Professional Formulas 🟢 Safety: 95/100
Brand: Clinical Synergy Professional Formulas
🟢 95/100

This product looks safe

  • Niacin: 50mg is 1.4× the Tolerable Upper Intake Level (35mg)
  • 57% of ingredients have research evidence
C Label Compliance Grade

Product Label

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Safety Alerts

⚠️ Niacin: 50mg is 1.4× the Tolerable Upper Intake Level (35mg)

Label Data

2 Capsule(s) Serving Size
30 Servings
Other Combinations Product Type
57% Evidence Coverage

Supplement Facts — Evidence Check

50 mg (250% DV)
⚠️ Exceeds Tolerable Upper Intake Level by 1.4× (UL: 35 mg) 📚 193 studies (Tier A: 5, B: 63)
RDA 14mg This product: 50mg UL 35mg
4 mg (200% DV)
📊 3.1× RDA — above typical dose (UL: 100 mg) 📚 113 studies (Tier A: 3, B: 35)
RDA 1.3mg This product: 4mg UL 100mg
Calcium
20 mg (2% DV)
100 mg (25% DV)
📊 Market median: 4002.0mg (1 products) 📚 20 studies (Tier A: 0, B: 2)
This product: 100mg
GABA Herbal Support for Relaxation and Sleep Proprietary Blend
410 mg
Traditional Asian Regenerative Sleep Proprietary Blend
240 mg
0.5 mg
📊 Market median: 3.0mg (984 products) 📚 236 studies (Tier A: 2, B: 109)
This product: 0.5mg UL 10mg

Other Ingredients

Vegetarian Capsule Tapioca Flour Stearic Acid Silicon Dioxide Bamboo Cellulose

Label Claims — Verification

❓ All Other
❓ Structure/Function
All Other (97% of products) Structure/Function (86% of products) Nutrient (36% of products)

Target Groups

Vegan Vegetarian Adult (18 - 50 Years) Gluten Free

Product Information

📋 Directions for Use

Suggested Use: As a dietary supplement, take 2 capsules at bedtime, or as recommended by your healthcare practitioner.

⚠️ Warnings & Precautions

Warning: Reproductive harm - www.P65Warnings.ca.gov/food.

🧪 Formulation Notes

RegeneRest is a unique blend of nutrients and botanicals formulated to calm and relax while promoting restful, deep sleep. RegeneRest is fortified with melatonin and GABA support botanicals to promote gentle, non-habit forming restorative sleep while resetting circadian rhythms to provide a refreshing, rejuvenated feeling upon waking.

Research has shown that disruptions to the circadian rhythm can have negative effects on mental and physical health. Promotes restful sleep and daily restoration Promotes natural circadian rhythms

RegeneRest is Vegan/Vegetarian Safe, Gluten-free and Non-GMO

RegeneRest is Vegan/Vegetarian Safe, Gluten-free and Non-GMO

Formulated to promote restful sleep and daily restoration

Additional Information

Manufactured in the U.S.A.

Product Details

UPC / SKU 8 92985 00045 4
DSLD Entry Date 2020-04-23
Product Type Other Combinations
Form Capsule
Brand Clinical Synergy Professional Formulas
DSLD ID 216716
Data Updated 2026-04-11

Research Evidence

241 Research Sources
55 Avg Quality Score
113 Meta Analysis
75 Systematic Review
32 Rct
11 Clinical Trial
3 Other
3 Regulatory Source
1 Cochrane Review
1 Narrative Review
1 Openfda Safety
A Niacin for primary and secondary prevention of cardiovascular events
Meta Analysis The Cochrane database of systematic reviews 2017
PubMed DOI Cochrane
A Use of high potency statins and rates of admission for acute kidney injury: multicenter, retrospective observational analysis of administrative databases
Meta Analysis BMJ (Clinical research ed.) 2013
PubMed DOI
A Effect on cardiovascular risk of high density lipoprotein targeted drug treatments niacin, fibrates, and CETP inhibitors: meta-analysis of randomised controlled trials including 117,411 patients
Meta Analysis BMJ (Clinical research ed.) 2014
PubMed DOI
A A terminal metabolite of niacin promotes vascular inflammation and contributes to cardiovascular disease risk
Meta Analysis Nature medicine 2024
PubMed DOI
A Meta-analysis and imputation refines the association of 15q25 with smoking quantity
Meta Analysis Nature genetics 2010
PubMed DOI
A Genome-wide meta-analyses identify multiple loci associated with smoking behavior
Meta Analysis Nature genetics 2010
PubMed DOI
A Antidepressants for smoking cessation
Meta Analysis The Cochrane database of systematic reviews 2014
PubMed DOI
A Topical azelaic acid, salicylic acid, nicotinamide, sulphur, zinc and fruit acid (alpha-hydroxy acid) for acne
Meta Analysis The Cochrane database of systematic reviews 2020
PubMed DOI Cochrane
B Assessment of the Role of Niacin in Managing Cardiovascular Disease Outcomes: A Systematic Review and Meta-analysis
Meta Analysis JAMA network open 2019
PubMed DOI
B Association Between Lowering LDL-C and Cardiovascular Risk Reduction Among Different Therapeutic Interventions: A Systematic Review and Meta-analysis
Meta Analysis JAMA 2016
PubMed DOI
View all evidence for Niacin →

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