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E-400 Selenium

product on market Tablet or Pill Metagenics Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 75% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · methodology

Vitamin E and selenium provide antioxidant support to protect cells from oxidative stress, while calcium and phosphorus contribute to bone mineralization. Research providing strong evidence for these nutrients supports their roles in cellular health and skeletal integrity. Overall evidence coverage for this specific combination is limited.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for E-400 Selenium
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Tablet(s)
Serving Size
180
Servings
Other Combinations
Product Type
75%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

268 mg (1787% DV)
17.9× RDA — above typical dose (UL: 1000 mg) 179 studies (A:3, B:90)
Calcium
97 mg (7% DV)
74 mg (6% DV)
Within RDA (0.1× RDA) 13 studies (A:0, B:3)
50 mcg (91% DV)
Within RDA (0.9× RDA) 173 studies (A:0, B:67)

Other Ingredients

Dicalcium Phosphate Microcrystalline Cellulose Silica Stearic Acid Magnesium Stearate Croscarmellose Sodium Coating
Claims

Label Claims — Verification

Unverified Nutrient
Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Directions: Take one tablet up to twice daily with meals or as directed by your healthcare practitioner.

Warnings & Precautions

Caution: Keep out of the reach of children.

Tamper evident: Do not use if safety seal is missing or broken.

Formulation Notes

E-400 Selenium provides the essential trace mineral selenium and natural-source vitamin E, an antioxidant that helps protect tissues from damage caused by free radicals.

This product in non-GMO, gluten-free, and vegetarian.

This product in non-GMO, gluten-free, and vegetarian.

Antioxidant Formula

Additional Information

Storage: Keep tightly closed in a cool, dry place.

GF Certified Gluten-free

Practitioner exclusive

Metadata

Product Details

UPC / SKU7 55571 91017 2
DSLD Entry Date2020-03-24
Product TypeOther Combinations
FormTablet or Pill
BrandMetagenics
DSLD ID216323
Data Updated2026-04-11
Research

Research Evidence

273
Research Sources
55
Avg Quality
131
Meta Analysis
61
Systematic Review
55
Rct
19
Clinical Trial
2
Regulatory Source
1
Cochrane Review
1
Other
1
Observational
1
Openfda Safety
A Selenium for preventing cancer
Meta Analysis The Cochrane database of systematic reviews 2018 PubMed DOI
A Selenium supplementation for the primary prevention of cardiovascular disease
Meta Analysis The Cochrane database of systematic reviews 2013 PubMed DOI
A Selenium supplementation for critically ill adults
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
A Vitamin E and the risk of prostate cancer: the Selenium and Vitamin E Cancer Prevention Trial (SELECT)
Rct JAMA 2011 PubMed DOI
B Selenium and prostate cancer: systematic review and meta-analysis
Meta Analysis The American journal of clinical nutrition 2012 PubMed DOI
B Selenium supplementation for Hashimoto's thyroiditis
Systematic Review The Cochrane database of systematic reviews 2013 PubMed DOI
B Pharmacological interventions for preventing dry mouth and salivary gland dysfunction following radiotherapy
Meta Analysis The Cochrane database of systematic reviews 2017 PubMed DOI
B Selenium, antioxidants, cardiovascular disease, and all-cause mortality: a systematic review and meta-analysis of randomized controlled trials
Meta Analysis The American journal of clinical nutrition 2020 PubMed DOI
B The effect of selenium supplementation on coronary heart disease: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) 2017 PubMed DOI
B Meta-analysis of selenium effects on the meat quality of broilers
Meta Analysis Poultry science 2024 PubMed DOI
View all evidence for Selenium →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.