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Niatain

product on market Tablet or Pill Metagenics Safety: 87/100
87/100

This product is generally safe

  • Niacin: 500mg is 14.3× the Tolerable Upper Intake Level (35mg)
  • 67% of ingredients have research evidence
C Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · methodology

Niacin, calcium, and phosphorus are essential nutrients that support cellular energy production and skeletal integrity. Research provides strong evidence for their roles in metabolic function and bone health. However, the overall evidence coverage for this specific formulation is limited.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Niacin: 500mg is 14.3× the Tolerable Upper Intake Level (35mg)

Label

Product Label

Label for Niatain
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Tablet(s)
Serving Size
120
Servings
Other Combinations
Product Type
67%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

500 mg (3125% DV)
Exceeds UL by 14.3× (UL: 35 mg) 196 studies (A:5, B:63)
Calcium
40 mg (3% DV)
30 mg (2% DV)
Market median: 99.0mg (503 products) 13 studies (A:0, B:3)

Other Ingredients

Microcrystalline Cellulose Hydroxypropylmethylcellulose Magnesium Stearate Coating Silica
Claims

Label Claims — Verification

Unverified Nutrient
Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Directions: Take one tablet with a meal one to two times daily or as directed by your healthcare practitioner.

Warnings & Precautions

Caution: Niacin use may be associated with itching and/or flushing.

Warning: Do not use if pregnant or breastfeeding or if you have a history of gout or liver dysfunction. Larger than recommended doses of niacin have been associated with liver dysfunction. If taking cholesterol lowering medications, please discuss with your clinician prior to use.

Formulation Notes

Niatain features a high quality form of nicotinic acid in an extended release formula designed to reduce the flushing normally associated with niacin intake. It has been formulated with a non-wax coating for effective dissolution.

For decades, niacin has been extensively researched and endorsed as support for healthy lipid metabolism.

This product is non-GMO, gluten-free, and vegetarian.

This product is non-GMO, gluten-free, and vegetarian.

Support for healthy lipid metabolism

Additional Information

Storage: Keep tightly closed in a cool, dry place.

GF Certified Gluten-free

New formula

Practitioner exclusive

Metadata

Product Details

UPC / SKU7 55571 92407 0
DSLD Entry Date2020-03-24
Product TypeOther Combinations
FormTablet or Pill
BrandMetagenics
DSLD ID216308
Data Updated2026-04-11
Research

Research Evidence

241
Research Sources
55
Avg Quality
113
Meta Analysis
75
Systematic Review
32
Rct
11
Clinical Trial
3
Other
3
Regulatory Source
1
Cochrane Review
1
Narrative Review
1
Openfda Safety
A Niacin for primary and secondary prevention of cardiovascular events
Meta Analysis The Cochrane database of systematic reviews 2017 PubMed DOI
A Use of high potency statins and rates of admission for acute kidney injury: multicenter, retrospective observational analysis of administrative databases
Meta Analysis BMJ (Clinical research ed.) 2013 PubMed DOI
A Effect on cardiovascular risk of high density lipoprotein targeted drug treatments niacin, fibrates, and CETP inhibitors: meta-analysis of randomised controlled trials including 117,411 patients
Meta Analysis BMJ (Clinical research ed.) 2014 PubMed DOI
A A terminal metabolite of niacin promotes vascular inflammation and contributes to cardiovascular disease risk
Meta Analysis Nature medicine 2024 PubMed DOI
A Meta-analysis and imputation refines the association of 15q25 with smoking quantity
Meta Analysis Nature genetics 2010 PubMed DOI
A Genome-wide meta-analyses identify multiple loci associated with smoking behavior
Meta Analysis Nature genetics 2010 PubMed DOI
A Antidepressants for smoking cessation
Meta Analysis The Cochrane database of systematic reviews 2014 PubMed DOI
A Topical azelaic acid, salicylic acid, nicotinamide, sulphur, zinc and fruit acid (alpha-hydroxy acid) for acne
Meta Analysis The Cochrane database of systematic reviews 2020 PubMed DOI
B Assessment of the Role of Niacin in Managing Cardiovascular Disease Outcomes: A Systematic Review and Meta-analysis
Meta Analysis JAMA network open 2019 PubMed DOI
B Association Between Lowering LDL-C and Cardiovascular Risk Reduction Among Different Therapeutic Interventions: A Systematic Review and Meta-analysis
Meta Analysis JAMA 2016 PubMed DOI
View all evidence for Niacin →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.