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5-HTP (Griffonia Simplicifolia Extract) 100 mg

product on market Capsule Windmill Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 100% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · grounded in 1 source · methodology

This formula combines 5-HTP and Valerian, which have moderate evidence for supporting sleep and mood regulation. Niacin, Vitamin B6, and Magnesium serve as cofactors in neurotransmitter synthesis. Overall, clinical evidence for this specific combination is limited, though the individual components are well-studied.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for 5-HTP (Griffonia Simplicifolia Extract) 100 mg
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Capsule(s)
Serving Size
Other Combinations
Product Type
100%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

5 mg (31% DV)
Within RDA (0.4× RDA) 196 studies (A:5, B:63)
5 mg (294% DV)
3.8× RDA — above typical dose (UL: 100 mg) 114 studies (A:3, B:35)
25 mg (6% DV)
Within RDA (0.1× RDA) 316 studies (A:8, B:159)
Market median: 100.0mg (116 products) 18 studies (A:0, B:3)
50 mg
Market median: 300.0mg (214 products) 25 studies (A:0, B:6)

Other Ingredients

Rice Flour Gelatin Magnesium Stearate Silica
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Directions: Take 1 capsule, with meals as a dietary supplement or as directed by a healthcare professional.

Warnings & Precautions

Keep out of reach of children.

Do not purchase if seal is broken.

Formulation Notes

Supports a postive mood Promotes increased levels of serotonin

No sugar, yeast, wheat, soy, artificial colors, flavors or preservatives Gluten free

Additional Information

Protect from heat, light & moisture. Store in a cool, dry place.

Made in the U.S.A. from globally sourced ingredients.

Trusted since 1972 Natural vitamins Pharmacist recommended

Metadata

Product Details

UPC / SKU0 35046 00384 5
DSLD Entry Date2020-03-24
Product TypeOther Combinations
FormCapsule
BrandWindmill
DSLD ID215457
Data Updated2026-04-11
Research

Research Evidence

21
Research Sources
53
Avg Quality
11
Systematic Review
6
Rct
4
Meta Analysis
B Combination pharmacotherapy for the treatment of fibromyalgia in adults
Systematic Review The Cochrane database of systematic reviews 2018 PubMed DOI
B Tryptophan and 5-hydroxytryptophan for depression
Systematic Review The Cochrane database of systematic reviews 2001 PubMed
B Tryptophan and 5-hydroxytryptophan for depression
Systematic Review The Cochrane database of systematic reviews 2002 PubMed
B The impact of 5-hydroxytryptophan supplementation on sleep quality and gut microbiota composition in older adults: A randomized controlled trial
Rct Clinical nutrition (Edinburgh, Scotland) 2024 PubMed DOI
B The Impact of 5-Hydroxytryptophan Supplementation on Cognitive Function and Mood in Singapore Older Adults: A Randomized Controlled Trial
Rct Nutrients 2025 PubMed DOI
B The Efficacy of Different Triptans for the Treatment of Acute Headache in Pediatric Migraine: A Systematic Review
Systematic Review Indian pediatrics 2023 PubMed
B The effect of therapeutic massage combined with conventional therapy in children with functional dyspepsia: a systematic review and meta-analysis
Systematic Review Frontiers in pharmacology 2025 PubMed DOI
C Sleep disorders in children
Systematic Review BMJ clinical evidence 2010 PubMed
C Effects of 5-hydroxytryptophan on distinct types of depression: a systematic review and meta-analysis
Meta Analysis Nutrition reviews 2020 PubMed DOI
C Investigating genetic links between biological aging and adverse pregnancy outcomes
Meta Analysis Biogerontology 2025 PubMed DOI
View all evidence for 5 Htp →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.