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Niacin 500 mg

product on market Other (e.g. tea bag) Sundown Safety: 80/100
80/100

This product is generally safe

  • Niacin: 500mg is 14.3× the Tolerable Upper Intake Level (35mg)
  • 50% of ingredients have research evidence
C Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · methodology

Niacin is supported by strong evidence for managing lipid levels and supporting metabolic function. Calcium is well-documented for maintaining bone density and nerve signaling. Overall evidence coverage for this specific formulation is limited.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Niacin: 500mg is 14.3× the Tolerable Upper Intake Level (35mg)

Label

Product Label

Label for Niacin 500 mg
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Caplet(s)
Serving Size
Single Vitamin and Mineral
Product Type
50%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

500 mg (3125% DV)
Exceeds UL by 14.3× (UL: 35 mg) 196 studies (A:5, B:63)
Calcium
106 mg (8% DV)

Other Ingredients

Vegetable Cellulose Stearic Acid Vegetable Magnesium Stearate
Claims

Label Claims — Verification

Unverified Nutrient
Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Directions: For adults, take one (1) caplet daily, preferably with a meal. As a reminder, discuss the supplements and medications you take with your health care providers.

Warnings & Precautions

Keep out of reach of children.

Tamper Resistant: Do not use if seal under cap is broken or missing.

Warning: Not intended for use by pregnant or nursing women. If you are taking any meditations or have any medical condition, consult your doctor before use.

Discontinue use and consult your doctor if any adverse reactions occur. Notice: Use of this product may cause a temporary skin flushing (hot feeling and skin redness), burning, itching, or rash caused by an increase in blood flow near the skin. Sensitive individuals may experience unexpected drop of blood pressure or dizziness. Do not take on an empty stomach. Do not take more than the recommended dose unless prescribed by your doctor.

Formulation Notes

Clean Nutrition Sundown believes in clean nutrition and being transparent. That's why you won't find genetically modified ingredients, gluten, wheat, dairy, lactose or artificial flavors in any of our products. Non-GMO No gluten No wheat No milk No lactose No artificial color No artificial flavor No artificial sweetener No preservatives No sugar No soy No starch No yeast No peanuts No tree nuts No fish Sodium free

B Vitamins aid in the conversion of food into energy

Supports heart health & energy production

Vegetarian

Additional Information

Store at room temperature and avoid excessive heat.

Questions? Call toll free 1-888-VITAHELP (848-2435) or visit us at www.sundownnutrition.com Made in the USA with select ingredients from around the world US Only Discard seal & empty before recycling Check locally Plastic bottle how2recycle.info Not recycled in all communities

Metadata

Product Details

UPC / SKU0 30768 29505 9
DSLD Entry Date2019-12-22
Product TypeSingle Vitamin and Mineral
FormOther (e.g. tea bag)
BrandSundown
DSLD ID212387
Data Updated2026-04-11
Research

Research Evidence

241
Research Sources
55
Avg Quality
113
Meta Analysis
75
Systematic Review
32
Rct
11
Clinical Trial
3
Other
3
Regulatory Source
1
Cochrane Review
1
Narrative Review
1
Openfda Safety
A Niacin for primary and secondary prevention of cardiovascular events
Meta Analysis The Cochrane database of systematic reviews 2017 PubMed DOI
A Use of high potency statins and rates of admission for acute kidney injury: multicenter, retrospective observational analysis of administrative databases
Meta Analysis BMJ (Clinical research ed.) 2013 PubMed DOI
A Effect on cardiovascular risk of high density lipoprotein targeted drug treatments niacin, fibrates, and CETP inhibitors: meta-analysis of randomised controlled trials including 117,411 patients
Meta Analysis BMJ (Clinical research ed.) 2014 PubMed DOI
A A terminal metabolite of niacin promotes vascular inflammation and contributes to cardiovascular disease risk
Meta Analysis Nature medicine 2024 PubMed DOI
A Meta-analysis and imputation refines the association of 15q25 with smoking quantity
Meta Analysis Nature genetics 2010 PubMed DOI
A Genome-wide meta-analyses identify multiple loci associated with smoking behavior
Meta Analysis Nature genetics 2010 PubMed DOI
A Antidepressants for smoking cessation
Meta Analysis The Cochrane database of systematic reviews 2014 PubMed DOI
A Topical azelaic acid, salicylic acid, nicotinamide, sulphur, zinc and fruit acid (alpha-hydroxy acid) for acne
Meta Analysis The Cochrane database of systematic reviews 2020 PubMed DOI
B Assessment of the Role of Niacin in Managing Cardiovascular Disease Outcomes: A Systematic Review and Meta-analysis
Meta Analysis JAMA network open 2019 PubMed DOI
B Association Between Lowering LDL-C and Cardiovascular Risk Reduction Among Different Therapeutic Interventions: A Systematic Review and Meta-analysis
Meta Analysis JAMA 2016 PubMed DOI
View all evidence for Niacin →
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Niacin research Best Niacin All Niacin products More from Sundown View on NIH DSLD →

This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.