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Systolex

product on market Tablet or Pill PurMedica Safety: 95/100
95/100

This product looks safe

  • Magnesium: 550mg is 1.6× the Tolerable Upper Intake Level (350mg)
  • 43% of ingredients have research evidence
C Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · methodology

This formula combines calcium and magnesium for cardiovascular support with hawthorn berry and olive leaf extracts, which have moderate evidence for supporting blood pressure and heart health. Taurine provides additional metabolic support. Overall, the evidence coverage for this specific ingredient profile is limited.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Magnesium: 550mg is 1.6× the Tolerable Upper Intake Level (350mg)

Label

Product Label

Label for Systolex
Open Full PDF View on NIH DSLD →
Details

Label Data

3 Tablet(s)
Serving Size
30
Servings
Other Combinations
Product Type
43%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Calcium
250 mg (25% DV)
550 mg (138% DV)
Exceeds UL by 1.6× (UL: 350 mg) 316 studies (A:8, B:159)
Market median: 333.0mg (166 products) 9 studies (A:0, B:2)
Market median: 500.0mg (115 products)
200 mg
Market median: 500.0mg (180 products) 5 studies (A:0, B:1)
Coleus forskohlii extract
200 mg
Market median: 630.0mg (46 products)

Other Ingredients

Cellulose modified Cellulose Gum Magnesium Stearate Silica Glycerin
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Suggested Use: As a dietary supplement, adults take three (3) tablets daily, or as directed by a health care professional.

Warnings & Precautions

Keep out of reach of children

Formulation Notes

Contains no added sugar, salt, dairy, yeast, wheat, corn, soy, preservatives, artificial colors or flavors.

Supports blodd pressure health

Additional Information

Store in a cool, dry place and away from direct light.

Quality and potency guaranteed.

Naturally healthy

Metadata

Product Details

DSLD Entry Date2020-01-25
Product TypeOther Combinations
FormTablet or Pill
BrandPurMedica
DSLD ID211679
Data Updated2026-04-11
Research

Research Evidence

849
Research Sources
56
Avg Quality
450
Meta Analysis
152
Rct
137
Systematic Review
73
Clinical Trial
11
Regulatory Source
7
Other
7
Guideline
3
Openfda Safety
2
Cochrane Review
2
Observational
A Phosphate binders for preventing and treating chronic kidney disease-mineral and bone disorder (CKD-MBD)
Meta Analysis The Cochrane database of systematic reviews 2018 PubMed DOI
A Calcium supplementation (other than for preventing or treating hypertension) for improving pregnancy and infant outcomes
Meta Analysis The Cochrane database of systematic reviews 2024 PubMed DOI
A Calcium supplementation (other than for preventing or treating hypertension) for improving pregnancy and infant outcomes
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
A Vitamin and mineral supplementation for maintaining cognitive function in cognitively healthy people in mid and late life
Meta Analysis The Cochrane database of systematic reviews 2018 PubMed DOI
A Calcium supplementation during pregnancy for preventing hypertensive disorders and related problems
Meta Analysis The Cochrane database of systematic reviews 2025 PubMed DOI
A Dietary calcium supplementation for preventing colorectal cancer and adenomatous polyps
Systematic Review The Cochrane database of systematic reviews 2008 PubMed DOI
A Calcium and vitamin D for increasing bone mineral density in premenopausal women
Systematic Review The Cochrane database of systematic reviews 2023 PubMed DOI
A Dietary sodium, sodium-to-potassium ratio, and risk of stroke: A systematic review and nonlinear dose-response meta-analysis
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2019 PubMed DOI
A The association between circulating magnesium and clinically relevant outcomes in patients with chronic kidney disease: A systematic review and meta-analysis
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2021 PubMed DOI
A Calcium channel blockers versus other classes of drugs for hypertension
Systematic Review The Cochrane database of systematic reviews 2021 PubMed DOI
View all evidence for Electrolytes →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.