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Triple Flex with Vitamin D3

product on market Other (e.g. tea bag) Nature Made Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 60% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · methodology

Glucosamine, chondroitin, and MSM are commonly used to support joint health, though research shows mixed or limited evidence regarding their efficacy. Vitamin D3 is strongly supported for maintaining bone density and immune function. These ingredients are generally considered safe for most adults.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for Triple Flex with Vitamin D3
Open Full PDF View on NIH DSLD →
Details

Label Data

2 Caplet(s)
Serving Size
60
Servings
Other Combinations
Product Type
60%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

2000 IU (500% DV)
3.3× RDA — above typical dose (UL: 0.1 mg) 608 studies (A:16, B:251)
Sodium
70 mg (3% DV)
Market median: 1000.0mg (1115 products) 24 studies (A:0, B:9)
Market median: 600.0mg (79 products) 25 studies (A:0, B:6)
Market median: 1000.0mg (2 products)

Other Ingredients

Glucosamine Hydrochloride Sodium Chondroitin Sulfate Methylsulfonylmethane Hydroxypropyl MethylCellulose Color added Silicon Dioxide Magnesium Stearate Glyceryl Behenate Polyethylene Glycol Corn Starch Triethyl Citrate Polysorbate 80 Vitamin D3
Claims

Label Claims — Verification

Unverified Nutrient
Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

2 caplets per day

Suggested use: Take two caplets daily, with food. Caplets can be taken together or at different times during the day. Take 4-6 weeks to see results.

Warnings & Precautions

Store in a cool, dry place, out of reach of children.

Do not use if imprinted seal under cap is broken or missing.

Caution: If you are pregnant or nursing, or allergic to shellfish, consult your health care professional before taking this product.

Contains: Shellfish (shrimp & crab).

Caution: If you are pregnant or nursing, or allergic to shellfish, consult your health care professional before taking this product

Formulation Notes

Comfort Mobility Flexibility

Triple strength

Glucosamine 1500 mg Chondroitin 800 mg MSM 750 mg Vitamin D3 2000 IU

Color derived for natural source

No synthetic dyes No artificial flavors No preservatives No yeast Gluten free

Additional Information

Proud sponsor of the Arthritis Foundation www.arthritis.org (see back

Keep bottle tightly closed. Store in a cool, dry place, out of reach of children.

Tableted and quality tested in the U.S.A.

TripleFlex with Vitamin D3 caplets are made to Nature Made's guaranteed purity and potency standards. Valid only for U.S. and Puerto Rico residents.

Metadata

Product Details

DSLD Entry Date2020-02-26
Product TypeOther Combinations
FormOther (e.g. tea bag)
BrandNature Made
DSLD ID211265
Data Updated2026-04-11
Research

Research Evidence

872
Research Sources
53
Avg Quality
309
Meta Analysis
309
Clinical Trial
111
Rct
71
Systematic Review
55
Guideline
4
Cochrane Review
4
Regulatory Source
2
Other
2
Narrative Review
2
Observational
1
Openfda Safety
A Vitamin D and vitamin D analogues for preventing fractures associated with involutional and post-menopausal osteoporosis
Meta Analysis The Cochrane database of systematic reviews 2009 PubMed DOI
A Vitamin D supplementation for prevention of mortality in adults
Meta Analysis The Cochrane database of systematic reviews 2014 PubMed DOI
A Vitamin D and vitamin D analogues for preventing fractures in post-menopausal women and older men
Meta Analysis The Cochrane database of systematic reviews 2014 PubMed DOI
A Vitamin D supplementation for prevention of cancer in adults
Meta Analysis The Cochrane database of systematic reviews 2014 PubMed DOI
A Interventions for preventing falls in older people in care facilities and hospitals
Meta Analysis The Cochrane database of systematic reviews 2018 PubMed DOI
A Drugs for preventing lung cancer in healthy people
Meta Analysis The Cochrane database of systematic reviews 2020 PubMed DOI
A Vitamin D supplementation for prevention of mortality in adults
Meta Analysis The Cochrane database of systematic reviews 2011 PubMed DOI
A High prevalence of vitamin D deficiency in Asia: A systematic review and meta-analysis
Meta Analysis Critical reviews in food science and nutrition 2023 PubMed DOI
A The effect of vitamin D supplementation on depressive symptoms in adults: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Critical reviews in food science and nutrition 2023 PubMed DOI
A Interventions for preventing falls in older people living in the community
Meta Analysis The Cochrane database of systematic reviews 2009 PubMed DOI
View all evidence for Vitamin D →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.