🟢 100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 60% of ingredients have research evidence
A Label Compliance Grade

Product Label

📸

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Label Data

2 Caplet(s) Serving Size
60 Servings
Other Combinations Product Type
60% Evidence Coverage

Supplement Facts — Evidence Check

2000 IU (500% DV)
📊 3.3× RDA — above typical dose (UL: 0.1 mg) 📚 604 studies (Tier A: 16, B: 251)
RDA 0.015mg This product: 0.05mg UL 0.1mg
Sodium
70 mg (3% DV)
📊 Market median: 1000.0mg (1115 products) 📚 22 studies (Tier A: 0, B: 9)
This product: 1.5mg
📊 Market median: 600.0mg (79 products) 📚 24 studies (Tier A: 0, B: 6)
This product: 800mg
📊 Market median: 1000.0mg (2 products)
This product: 750mg

Other Ingredients

Glucosamine Hydrochloride Sodium Chondroitin Sulfate Methylsulfonylmethane Hydroxypropyl MethylCellulose Color added Silicon Dioxide Magnesium Stearate Glyceryl Behenate Polyethylene Glycol Corn Starch Triethyl Citrate Polysorbate 80 Vitamin D3

Label Claims — Verification

Nutrient
All Other
Structure/Function
All Other (99% of products) Structure/Function (85% of products) Nutrient (70% of products) Approved Health (4% of products)

Target Groups

Adult (18 - 50 Years) Gluten Free

Product Information

📋 Directions for Use

2 caplets per day

Suggested use: Take two caplets daily, with food. Caplets can be taken together or at different times during the day. Take 4-6 weeks to see results.

⚠️ Warnings & Precautions

Store in a cool, dry place, out of reach of children.

Do not use if imprinted seal under cap is broken or missing.

Caution: If you are pregnant or nursing, or allergic to shellfish, consult your health care professional before taking this product.

Contains: Shellfish (shrimp & crab).

Caution: If you are pregnant or nursing, or allergic to shellfish, consult your health care professional before taking this product

🧪 Formulation Notes

Comfort Mobility Flexibility

Triple strength

Glucosamine 1500 mg Chondroitin 800 mg MSM 750 mg Vitamin D3 2000 IU

Color derived for natural source

No synthetic dyes No artificial flavors No preservatives No yeast Gluten free

Additional Information

Proud sponsor of the Arthritis Foundation www.arthritis.org (see back

Keep bottle tightly closed. Store in a cool, dry place, out of reach of children.

Tableted and quality tested in the U.S.A.

TripleFlex with Vitamin D3 caplets are made to Nature Made's guaranteed purity and potency standards. Valid only for U.S. and Puerto Rico residents.

Product Details

DSLD Entry Date 2020-02-26
Product Type Other Combinations
Form Other (e.g. tea bag)
Brand Nature Made
DSLD ID 211265
Data Updated 2026-04-11

Research Evidence

872 Research Sources
53 Avg Quality Score
309 Meta Analysis
309 Clinical Trial
111 Rct
71 Systematic Review
55 Guideline
4 Cochrane Review
4 Regulatory Source
2 Other
2 Narrative Review
2 Observational
1 Openfda Safety
A Vitamin D and vitamin D analogues for preventing fractures associated with involutional and post-menopausal osteoporosis
Meta Analysis The Cochrane database of systematic reviews 2009
A Vitamin D supplementation for prevention of mortality in adults
Meta Analysis The Cochrane database of systematic reviews 2014
A Vitamin D and vitamin D analogues for preventing fractures in post-menopausal women and older men
Meta Analysis The Cochrane database of systematic reviews 2014
A Vitamin D supplementation for prevention of cancer in adults
Meta Analysis The Cochrane database of systematic reviews 2014
A Interventions for preventing falls in older people in care facilities and hospitals
Meta Analysis The Cochrane database of systematic reviews 2018
A Drugs for preventing lung cancer in healthy people
Meta Analysis The Cochrane database of systematic reviews 2020
A Vitamin D supplementation for prevention of mortality in adults
Meta Analysis The Cochrane database of systematic reviews 2011
A High prevalence of vitamin D deficiency in Asia: A systematic review and meta-analysis
Meta Analysis Critical reviews in food science and nutrition 2023
A The effect of vitamin D supplementation on depressive symptoms in adults: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Critical reviews in food science and nutrition 2023
A Interventions for preventing falls in older people living in the community
Meta Analysis The Cochrane database of systematic reviews 2009
View all evidence for Vitamin D →

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