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Niacin Vitamin B3

product on market Capsule Allergy Research Group Safety: 60/100
60/100

Review before taking

  • Niacin: 250mg is 7.1× the Tolerable Upper Intake Level (35mg)
  • 100% of ingredients have research evidence
C Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · grounded in 1 source · methodology

Niacin is used to support cholesterol levels and cellular energy production, though evidence for specific health outcomes is limited in this context. Due to a safety score of 60, users should be aware of potential concerns such as flushing or liver toxicity. Consult a professional regarding appropriate dosages.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Niacin: 250mg is 7.1× the Tolerable Upper Intake Level (35mg)

AI-generated · Qwen 3.6 · grounded in 2 sources · methodology

This product received a low safety score because it contains 250mg of Niacin, which is over seven times the recommended maximum daily limit.

Label

Product Label

Label for Niacin Vitamin B3
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Capsule(s)
Serving Size
90
Servings
Vitamin
Product Type
100%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

250 mg NE (1563% DV)
Exceeds UL by 7.1× (UL: 35 mg) 196 studies (A:5, B:63)

Other Ingredients

Hydroxypropyl Methylcellulose L-Leucine
Claims

Label Claims — Verification

Unverified Nutrient
Unverified All Other
Info

Product Information

Directions for Use

Suggested Use As a dietary supplement, 1 capsule two or three times daily with meals, or as directed by a healthcare practitioner.

Warnings & Precautions

Warning: Niacin can cause skin flushing and tingling (the "niacin flush").

Do not take large amounts of Niacin (greater than 1.5 grams per day) without first consulting a healthcare practitioner.

Formulation Notes

Also known as nicotinic acid, niacin is a B vitamin and an essential nutrient.

Hypoallergenic

Additional Information

Keep in a cool, dry place, tightly capped.

Metadata

Product Details

UPC / SKU7 13947 70360 5
DSLD Entry Date2019-10-23
Product TypeVitamin
FormCapsule
DSLD ID208198
Data Updated2026-04-11
Research

Research Evidence

241
Research Sources
55
Avg Quality
113
Meta Analysis
75
Systematic Review
32
Rct
11
Clinical Trial
3
Other
3
Regulatory Source
1
Cochrane Review
1
Narrative Review
1
Openfda Safety
A Niacin for primary and secondary prevention of cardiovascular events
Meta Analysis The Cochrane database of systematic reviews 2017 PubMed DOI
A Use of high potency statins and rates of admission for acute kidney injury: multicenter, retrospective observational analysis of administrative databases
Meta Analysis BMJ (Clinical research ed.) 2013 PubMed DOI
A Effect on cardiovascular risk of high density lipoprotein targeted drug treatments niacin, fibrates, and CETP inhibitors: meta-analysis of randomised controlled trials including 117,411 patients
Meta Analysis BMJ (Clinical research ed.) 2014 PubMed DOI
A A terminal metabolite of niacin promotes vascular inflammation and contributes to cardiovascular disease risk
Meta Analysis Nature medicine 2024 PubMed DOI
A Meta-analysis and imputation refines the association of 15q25 with smoking quantity
Meta Analysis Nature genetics 2010 PubMed DOI
A Genome-wide meta-analyses identify multiple loci associated with smoking behavior
Meta Analysis Nature genetics 2010 PubMed DOI
A Antidepressants for smoking cessation
Meta Analysis The Cochrane database of systematic reviews 2014 PubMed DOI
A Topical azelaic acid, salicylic acid, nicotinamide, sulphur, zinc and fruit acid (alpha-hydroxy acid) for acne
Meta Analysis The Cochrane database of systematic reviews 2020 PubMed DOI
B Assessment of the Role of Niacin in Managing Cardiovascular Disease Outcomes: A Systematic Review and Meta-analysis
Meta Analysis JAMA network open 2019 PubMed DOI
B Association Between Lowering LDL-C and Cardiovascular Risk Reduction Among Different Therapeutic Interventions: A Systematic Review and Meta-analysis
Meta Analysis JAMA 2016 PubMed DOI
View all evidence for Niacin →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.