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L-Tryptophan 500 mg

product on market Capsule California Academy of Health Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • Limited research evidence available for ingredients
B Label Compliance Grade
Label

Product Label

Label for L-Tryptophan 500 mg
Open Full PDF View on NIH DSLD →
Details

Label Data

2 Capsule(s)
Serving Size
30
Servings
Amino acid/Protein
Product Type
0%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

1000 mg
Market median: 500.0mg (70 products)

Other Ingredients

Cellulose Cellulose Stearic Acid
Claims

Label Claims — Verification

Unverified Nutrient
Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Suggested usage: As a dietary supplement, take 1-2 Vcaps 2 to 3 times daily on an empty stomach or as directed by a healthcare professional. Best used at bedtime. Consider taking this product in combination with CAOH Natural Calm or Calming Plus.

Warnings & Precautions

Warning: Keep out of reach of children.

Pregnant/lactating women, those taking anti-depressant medications (such as SSRI's or MAOI's), and those with liver disorders, consult a healthcare professional before using this product.

May cause drowsiness. Caution: Do not eat freshness packet. Keep packet in bottle.

Formulation Notes

L-Tryptophan: an essential amino acid important in human nutrition for the synthesis of melatonin, serotonin, and hormones regulating sleep.

CAOH L- Tryptophan is pharmaceutically certified pure (USP) - every lot is tested to be free of Peak E and microbial contamination.

Certified vegetarian

No preservatives

Contains no: Sugar, salt, yeast, wheat, gluten, soy, milk, eggs, shellfish, or preservatives.

Vegetarian/Vegan product.

Additional Information

It also supports positive mood and immune function. As an essential amino acid, it is not synthesized by the body and must be obtained from the diet.

Supports relaxation & sleep Encourages positive mood

Metadata

Product Details

UPC / SKU8 96291 00241 6
DSLD Entry Date2019-09-24
Product TypeAmino acid/Protein
FormCapsule
DSLD ID206315
Data Updated2026-04-11
Research

Research Evidence

29
Research Sources
48
Avg Quality
19
Rct
5
Meta Analysis
3
Systematic Review
2
Clinical Trial
B Prebiotic and probiotic supplementation and the tryptophan-kynurenine pathway: A systematic review and meta analysis
Meta Analysis Neuroscience and biobehavioral reviews 2021 PubMed DOI
B Tryptophan and 5-hydroxytryptophan for depression
Systematic Review The Cochrane database of systematic reviews 2001 PubMed
B Tryptophan and 5-hydroxytryptophan for depression
Systematic Review The Cochrane database of systematic reviews 2002 PubMed
B The impact of tryptophan supplementation on sleep quality: a systematic review, meta-analysis, and meta-regression
Meta Analysis Nutrition reviews 2022 PubMed DOI
B No effects of acute tryptophan depletion on anxiety or mood in weight-recovered female patients with anorexia nervosa
Rct European archives of psychiatry and clinical neuroscience 2023 PubMed DOI
C The association between tryptophan levels and postpartum mood disorders: a systematic review and meta-analysis
Meta Analysis BMC psychiatry 2022 PubMed DOI
C A systematic review of the effect of L-tryptophan supplementation on mood and emotional functioning
Systematic Review Journal of dietary supplements 2021 PubMed DOI
C Comparison between Acupuncture and Nutraceutical Treatment with Migratens® in Patients with Fibromyalgia Syndrome: A Prospective Randomized Clinical Trial.
Rct Nutrients PubMed DOI
C Intake of Lactiplantibacillus plantarum HEAL9 Improves Cognition in Moderately Stressed Subjects: A Randomized Controlled Study.
Rct Nutrients PubMed DOI
C Are tryptophan and 5-hydroxytryptophan effective treatments for depression? A meta-analysis
Meta Analysis The Australian and New Zealand journal of psychiatry 2002 PubMed
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.