Home/ Supplements/ Niacin/ Niacinamide 500 mg

Niacinamide 500 mg

product on market Capsule The Vitamin Shoppe Safety: 60/100
60/100

Review before taking

  • Niacin: 500mg is 14.3× the Tolerable Upper Intake Level (35mg)
  • 100% of ingredients have research evidence
C Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · grounded in 1 source · methodology

Niacin is used to support cholesterol levels and skin health, though evidence for this specific formulation is limited. A safety score of 60 suggests potential concerns, such as the risk of flushing or liver enzyme elevations. Users should monitor for adverse reactions.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Niacin: 500mg is 14.3× the Tolerable Upper Intake Level (35mg)

✨ AI-generated · Qwen 3.6 · grounded in 2 sources · methodology

This product received a low safety score because it contains 500mg of Niacin, which is over 14 times the recommended upper limit for daily intake.

Label

Product Label

Label for Niacinamide 500 mg
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Capsule(s)
Serving Size
Vitamin
Product Type
100%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

500 mg NE (3125% DV)
Exceeds UL by 14.3× (UL: 35 mg) 196 studies (A:5, B:63)

Other Ingredients

Gelatin Magnesium Stearate Rice Flour
Claims

Label Claims — Verification

Unverified Nutrient
Unverified All Other
Info

Product Information

Directions for Use

Directions: Take one (1) capsule daily, preferably with a meal.

Warnings & Precautions

Warning: This product contains niacin, which should be taken with food. If taken on an empty stomach, niacin may cause temporary flushing.

Keep out of reach of children.

Tamper evident Do not use if outer seal is broken or missing.

Formulation Notes

Gluten free Dairy free Soy free Nut free

Does not contain: Gluten, sugar, salt, preservatives, artificial colors or flavors.

Warning: This product contains niacin, which should be taken with food.

Additional Information

Vitamin

Store in a cool, dry place.

Visit www.vitaminshoppe.com or call 1-800-223-1216 for more information and to reorder.

Quality Promise Tested & Trusted

Metadata

Product Details

UPC / SKU7 66536 01532 0
DSLD Entry Date2019-07-24
Product TypeVitamin
FormCapsule
BrandThe Vitamin Shoppe
DSLD ID204850
Data Updated2026-04-11
Research

Research Evidence

241
Research Sources
55
Avg Quality
113
Meta Analysis
75
Systematic Review
32
Rct
11
Clinical Trial
3
Other
3
Regulatory Source
1
Cochrane Review
1
Narrative Review
1
Openfda Safety
A Niacin for primary and secondary prevention of cardiovascular events
Meta Analysis The Cochrane database of systematic reviews 2017 PubMed DOI
A Use of high potency statins and rates of admission for acute kidney injury: multicenter, retrospective observational analysis of administrative databases
Meta Analysis BMJ (Clinical research ed.) 2013 PubMed DOI
A Effect on cardiovascular risk of high density lipoprotein targeted drug treatments niacin, fibrates, and CETP inhibitors: meta-analysis of randomised controlled trials including 117,411 patients
Meta Analysis BMJ (Clinical research ed.) 2014 PubMed DOI
A A terminal metabolite of niacin promotes vascular inflammation and contributes to cardiovascular disease risk
Meta Analysis Nature medicine 2024 PubMed DOI
A Meta-analysis and imputation refines the association of 15q25 with smoking quantity
Meta Analysis Nature genetics 2010 PubMed DOI
A Genome-wide meta-analyses identify multiple loci associated with smoking behavior
Meta Analysis Nature genetics 2010 PubMed DOI
A Antidepressants for smoking cessation
Meta Analysis The Cochrane database of systematic reviews 2014 PubMed DOI
A Topical azelaic acid, salicylic acid, nicotinamide, sulphur, zinc and fruit acid (alpha-hydroxy acid) for acne
Meta Analysis The Cochrane database of systematic reviews 2020 PubMed DOI
B Assessment of the Role of Niacin in Managing Cardiovascular Disease Outcomes: A Systematic Review and Meta-analysis
Meta Analysis JAMA network open 2019 PubMed DOI
B Association Between Lowering LDL-C and Cardiovascular Risk Reduction Among Different Therapeutic Interventions: A Systematic Review and Meta-analysis
Meta Analysis JAMA 2016 PubMed DOI
View all evidence for Niacin →
Compare

Similar Products

Serotone 5HTP 50 mg
Higher Nature · Capsule
100
Serotone 5HTP 100 mg
Higher Nature · Capsule
100
ChromeMate
NOW · Capsule
100
ChromeMate 200 mcg
Protocol For Life Balance · Capsule
100
Non Flush Niacin
Highland Laboratories · Capsule
100
View all Niacin products →
Niacin research Best Niacin All Niacin products More from The Vitamin Shoppe View on NIH DSLD →

This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.