🟢 90/100

This product looks safe

  • Contains proprietary blend — exact ingredient amounts not disclosed
  • 25% of ingredients have research evidence
B Label Compliance Grade

Product Label

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Safety Alerts

ℹ️ Contains proprietary blend — exact ingredient amounts not disclosed

Label Data

17.7 Gram(s) Serving Size
20 Servings
Other Combinations Product Type
25% Evidence Coverage

Supplement Facts — Evidence Check

Calories
50 Calorie(s)
Total Carbohydrates
1 Gram(s) (1% DV)
150 mcg (38% DV)
✅ Within RDA (0.4× RDA of 0.4 mg) 📚 225 studies (Tier A: 10, B: 105)
RDA 0.4mg This product: 0.15mg UL 1.0mg
150 mg (38% DV)
📊 Market median: 4002.0mg (1 products) 📚 20 studies (Tier A: 0, B: 2)
This product: 150mg
2.5 Gram(s)
📊 Market median: 500.0mg (143 products)
This product: 2.5mg
Glycine
4 Gram(s)
3 Gram(s)
📊 Market median: 500.0mg (143 products)
This product: 3mg
Proprietary Blend
3.3 Gram(s)

Other Ingredients

Malic Acid Citric Acid Natural flavors Beet juice powder Silica Glucose Polymers Acesulfame Potassium Sucralose

Label Claims — Verification

Nutrient
All Other
Structure/Function
All Other (99% of products) Structure/Function (77% of products) Nutrient (60% of products) Approved Health (5% of products)

Target Groups

Adult (18 - 50 Years) Seniors/Mature (>50 Years)

Product Information

📋 Directions for Use

Directions for use: Use only as directed. Mix one scoop is 8 to 10 fl. oz. of water. Take 30-60 minutes before bedtime or at least 45 minutes prior to weight training/aerobic exercise activity. For best results, do not eat 1 1/2 to 2 hours prior to or after use. Take consecutively for six days, skipping the seventh day, and repeat.

⚠️ Warnings & Precautions

Warning: For use only by individuals 30 years of age or older.

Consult a healthcare provider before using this product if you are taking any prescription medications, have had liver or kidney disease, uncontrolled diabetes, hypertension, benign or malignant tumors, or any of the ingredients or if you are pregnant or breastfeeding. L-arginine may impact blood pressure medication.

Keep out of the reach of children.

Do not purchase if seal is broken.

If barcode is missing or marked through, the sale of this product is not authorized or guaranteed by Market America.

Contains: Milk and salmon.

🧪 Formulation Notes

With L-arginine aspartate

L-arginine may impact blood pressure medication.

Contains: Milk and salmon.

Additional Information

Anti-aging nutraceuticals (HGH enhancer)

Prime Secretagogue works with your body to help naturally stimulate the pituitary gland, resulting in increased human growth hormone (HGH) secretion and release. Increased HGH levels have been associated with health benefits, including increased lean body mass and help maintain a healthy immune system and support sexual vitality.

Store at 59-86(0)F (15-30(0)C). Protect from heat, light and moisture.

Product Details

UPC / SKU 8 48570 00329 4
DSLD Entry Date 2019-06-24
Product Type Other Combinations
Form Powder
Brand Prime
DSLD ID 204063
Data Updated 2026-04-11

Research Evidence

363 Research Sources
57 Avg Quality Score
187 Meta Analysis
56 Systematic Review
54 Rct
29 Guideline
26 Clinical Trial
6 Cochrane Review
2 Regulatory Source
1 Other
1 Openfda Safety
A Homocysteine-lowering interventions for preventing cardiovascular events
Meta Analysis The Cochrane database of systematic reviews 2017
A Community-based intervention packages for reducing maternal and neonatal morbidity and mortality and improving neonatal outcomes
Meta Analysis The Cochrane database of systematic reviews 2015
A Folate Intake and Risk of Pancreatic Cancer: A Systematic Review and Updated Meta-Analysis of Epidemiological Studies
Meta Analysis Digestive diseases and sciences 2021
A The Association Between the Risk of Hypertensive Disorders of Pregnancy and Folic Acid: A Systematic Review and Meta-Analysis
Meta Analysis Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques 2021
A A Comparative Study Evaluating the Effectiveness of Folate-Based B Vitamin Intervention on Cognitive Function of Older Adults under Mandatory Folic Acid Fortification Policy: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
Meta Analysis Nutrients 2024
A Associations between serum Homocysteine, vitamin B9, and vitamin B12 levels and the formation of intracranial Aneurysms: A systematic review and meta-analysis
Meta Analysis Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 2025
A Intake of vitamin B6, folate, and vitamin B12 and risk of coronary heart disease: a systematic review and dose-response meta-analysis of prospective cohort studies
Meta Analysis Critical reviews in food science and nutrition 2019
A Beneficial effects of folic acid supplementation on lipid markers in adults: A GRADE-assessed systematic review and dose-response meta-analysis of data from 21,787 participants in 34 randomized controlled trials
Meta Analysis Critical reviews in food science and nutrition 2022
A Folic acid supplementation and blood pressure: a GRADE-assessed systematic review and dose-response meta-analysis of 41,633 participants
Meta Analysis Critical reviews in food science and nutrition 2023
A Digital tracking, provider decision support systems, and targeted client communication via mobile devices to improve primary health care
Meta Analysis The Cochrane database of systematic reviews 2025
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