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SAM-e 200 mg

product on market Tablet or Pill up&up Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • Limited research evidence available for ingredients
B Label Compliance Grade
Label

Product Label

Label for SAM-e 200 mg
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Tablet(s)
Serving Size
Non-Nutrient/Non-Botanical
Product Type
0%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Market median: 500.0mg (193 products) 7 studies — no high-quality reviews

Other Ingredients

Cellulose Mannitol Polymethacrylate Vegetable Magnesium Stearate Contains Less Than 2% of
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Directions: For adults, take one (1) tablet six times daily, preferably on an empty stomach. In order to obtain maximum benefits, SAM-e should be taken at least 30 minutes prior to a meal.

Warnings & Precautions

As a reminder, discuss the supplements and medications you take with your health care providers.

WARNING: If you are pregnant, nursing, taking any medications or have any medical condition, consult your doctor before use.

KEEP OUT OF REACH OF CHILDREN.

Discontinue use and consult your doctor if any adverse reactions occur.

TAMPER RESISTANT: DO NOT USE IF BLISTER SEAL IS CUT, TORN OR OPEN.

Formulation Notes

No yeast, wheat, gluten, milk or milk derivatives, lactose, sugar, preservatives, soy, artificial flavor.

Additional Information

394293-01 EXP 05/14

BALANCE* SAM-e is the term used to describe S-adenosylmethionine, a vital substance that is found in most cells and is essential to many biochemical reactions in the body.* SAM-e supports mood and emotional well-being, and also supports healthy joint function and comfort.*

up&up(TM)

supports a positive mood and emotional well-being* helps support healthy joint function and comfort* easy to swallow

BALANCE*

Laboratory tested to meet strict quality control standards for potency, purity and disintegration.

STORE AT ROOM TEMPERATURE AND AVOID EXCESSIVE HEAT.

ID201431

094 02 1327 PROD. NO. 7116 B336221 11F

ACTUAL SIZE

Metadata

Product Details

UPC / SKU7 56880 07116 5
DSLD Entry Date2013-05-24
Product TypeNon-Nutrient/Non-Botanical
FormTablet or Pill
Brandup&up
DSLD ID20193
Data Updated2026-04-11
Research

Research Evidence

14
Research Sources
50
Avg Quality
8
Rct
4
Meta Analysis
2
Clinical Trial
B The Effect of Fenugreek in Type 2 Diabetes and Prediabetes: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
Meta Analysis International journal of molecular sciences 2023 PubMed DOI
B A randomized controlled clinical trial evaluating the effect of Trigonella foenum-graecum (fenugreek) versus glibenclamide in patients with diabetes
Rct African health sciences 2019 PubMed DOI
C The effect of fenugreek seed supplementation on serum irisin levels, blood pressure, and liver and kidney function in patients with type 2 diabetes mellitus: A parallel randomized clinical trial
Rct Complementary therapies in medicine 2020 PubMed DOI
C Effect of saffron and fenugreek on lowering blood glucose: A systematic review with meta-analysis
Meta Analysis Phytotherapy research : PTR 2023 PubMed DOI
C Effect of fenugreek on hyperglycaemia and hyperlipidemia in diabetes and prediabetes: A meta-analysis
Meta Analysis Journal of ethnopharmacology 2016 PubMed DOI
C Effect of fenugreek extract supplement on testosterone levels in male: A meta-analysis of clinical trials
Meta Analysis Phytotherapy research : PTR 2020 PubMed DOI
C Investigating the Effectiveness of Fenugreek on the Quantity of Breast Milk and the Level of Prolactin in Mothers of Preterm Newborns: A Randomized Controlled Clinical Trial
Rct Current drug research reviews 2025 PubMed DOI
C Clinical observation on trigonella foenum-graecum L. total saponins in combination with sulfonylureas in the treatment of type 2 diabetes mellitus
Rct Chinese journal of integrative medicine 2008 PubMed
C Impact of Fenugreek Supplementation on Obesity and Hyperglycemia Among Diabetic Adults in Saudi Arabia
Clinical Trial ClinicalTrials.gov 2025
C Fenugreek bread: a treatment for diabetes mellitus
Rct Journal of medicinal food 2009 PubMed DOI
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.