🟢 100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • Limited research evidence available for ingredients
B Label Compliance Grade

Product Label

📸

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Label Data

1 Tablet(s) Serving Size
Non-Nutrient/Non-Botanical Product Type
0% Evidence Coverage

Supplement Facts — Evidence Check

📊 Market median: 500.0mg (193 products) 📚 7 studies — no high-quality reviews
This product: 200mg

Other Ingredients

Cellulose Mannitol Polymethacrylate Vegetable Magnesium Stearate Contains Less Than 2% of

Label Claims — Verification

All Other
Structure/Function
All Other (99% of products) Structure/Function (79% of products) Nutrient (9% of products)

Target Groups

Adult (18 - 50 Years) Gluten Free Dairy Free Sugar Free

Product Information

📋 Directions for Use

Directions: For adults, take one (1) tablet six times daily, preferably on an empty stomach. In order to obtain maximum benefits, SAM-e should be taken at least 30 minutes prior to a meal.

⚠️ Warnings & Precautions

As a reminder, discuss the supplements and medications you take with your health care providers.

WARNING: If you are pregnant, nursing, taking any medications or have any medical condition, consult your doctor before use.

KEEP OUT OF REACH OF CHILDREN.

Discontinue use and consult your doctor if any adverse reactions occur.

TAMPER RESISTANT: DO NOT USE IF BLISTER SEAL IS CUT, TORN OR OPEN.

🧪 Formulation Notes

No yeast, wheat, gluten, milk or milk derivatives, lactose, sugar, preservatives, soy, artificial flavor.

Additional Information

394293-01 EXP 05/14

BALANCE* SAM-e is the term used to describe S-adenosylmethionine, a vital substance that is found in most cells and is essential to many biochemical reactions in the body.* SAM-e supports mood and emotional well-being, and also supports healthy joint function and comfort.*

up&up(TM)

supports a positive mood and emotional well-being* helps support healthy joint function and comfort* easy to swallow

BALANCE*

Laboratory tested to meet strict quality control standards for potency, purity and disintegration.

STORE AT ROOM TEMPERATURE AND AVOID EXCESSIVE HEAT.

ID201431

094 02 1327 PROD. NO. 7116 B336221 11F

ACTUAL SIZE

Product Details

UPC / SKU 7 56880 07116 5
DSLD Entry Date 2013-05-24
Product Type Non-Nutrient/Non-Botanical
Form Tablet or Pill
Brand up&up
DSLD ID 20193
Data Updated 2026-04-11

Research Evidence

14 Research Sources
50 Avg Quality Score
8 Rct
4 Meta Analysis
2 Clinical Trial
B The Effect of Fenugreek in Type 2 Diabetes and Prediabetes: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
Meta Analysis International journal of molecular sciences 2023
B A randomized controlled clinical trial evaluating the effect of Trigonella foenum-graecum (fenugreek) versus glibenclamide in patients with diabetes
Rct African health sciences 2019
C The effect of fenugreek seed supplementation on serum irisin levels, blood pressure, and liver and kidney function in patients with type 2 diabetes mellitus: A parallel randomized clinical trial
Rct Complementary therapies in medicine 2020
C Effect of saffron and fenugreek on lowering blood glucose: A systematic review with meta-analysis
Meta Analysis Phytotherapy research : PTR 2023
C Effect of fenugreek on hyperglycaemia and hyperlipidemia in diabetes and prediabetes: A meta-analysis
Meta Analysis Journal of ethnopharmacology 2016
C Effect of fenugreek extract supplement on testosterone levels in male: A meta-analysis of clinical trials
Meta Analysis Phytotherapy research : PTR 2020
C Investigating the Effectiveness of Fenugreek on the Quantity of Breast Milk and the Level of Prolactin in Mothers of Preterm Newborns: A Randomized Controlled Clinical Trial
Rct Current drug research reviews 2025
C Clinical observation on trigonella foenum-graecum L. total saponins in combination with sulfonylureas in the treatment of type 2 diabetes mellitus
Rct Chinese journal of integrative medicine 2008
C Impact of Fenugreek Supplementation on Obesity and Hyperglycemia Among Diabetic Adults in Saudi Arabia
Clinical Trial ClinicalTrials.gov 2025
C Fenugreek bread: a treatment for diabetes mellitus
Rct Journal of medicinal food 2009
View all evidence for Fenugreek →

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