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Ligatone Joint Complex

product on market Capsule Professional Botanicals Safety: 87/100
87/100

This product is generally safe

  • Manganese: 14mg is 1.3× the Tolerable Upper Intake Level (11mg)
  • Contains proprietary blend — exact ingredient amounts not disclosed
  • 46% of ingredients have research evidence
C Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · methodology

Glucosamine, chondroitin, and MSM are commonly used to support joint health and reduce discomfort, though research evidence for their efficacy is generally moderate. Vitamin C provides antioxidant support and is necessary for collagen synthesis. The ingredient profile maintains a high safety score, indicating a low risk of adverse effects for most users.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Manganese: 14mg is 1.3× the Tolerable Upper Intake Level (11mg)

Contains proprietary blend — exact ingredient amounts not disclosed

Label

Product Label

Label for Ligatone Joint Complex
Open Full PDF View on NIH DSLD →
Details

Label Data

2 Capsule(s)
Serving Size
30
Servings
Other Combinations
Product Type
46%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Market median: 1000.0mg (1115 products) 24 studies (A:0, B:9)
Market median: 600.0mg (79 products) 25 studies (A:0, B:6)
MSM
280 mg
Market median: 1000.0mg (2 products)
Vitamin C
128 mg (210% DV)
Vitamin C
34 mg (60% DV)
Calcium
46 mg (6% DV)
15 mg (4% DV)
Market median: 500.0mg (1 products) 316 studies (A:8, B:159)
36 mg (10% DV)
Within RDA (0.1× RDA) 316 studies (A:8, B:159)
4 mg (30% DV)
Within RDA (0.4× RDA) 263 studies (A:6, B:134)
14 mg (700% DV)
Exceeds UL by 1.3× (UL: 11 mg) 9 studies — no high-quality reviews
Proprietary Blend
162 mg

Other Ingredients

Vegetable Capsule
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Dosage: Two capsules two times a day, or as directed. Do not take if allergic to aspirin.

Warnings & Precautions

Do not take if allergic to aspirin.

Formulation Notes

Gluten free Non GMO No fillers 3x tested

Additional Information

Supports the joints' ability to increase mobility, lubrication, elasticity, flexibility and strength while repairing ligaments, tendons and cartilage.

Gluten free Non GMO

Made in USA

2 Please recycle

Premium quality

Est. 1980

Metadata

Product Details

UPC / SKU8 98175 00161 4
DSLD Entry Date2019-04-25
Product TypeOther Combinations
FormCapsule
BrandProfessional Botanicals
DSLD ID200488
Data Updated2026-04-11
Research

Research Evidence

39
Research Sources
50
Avg Quality
20
Rct
9
Meta Analysis
4
Clinical Trial
3
Systematic Review
1
Regulatory Source
1
Openfda Safety
B Interventions for the management of temporomandibular joint osteoarthritis
Systematic Review The Cochrane database of systematic reviews 2012 PubMed DOI
B Glucosamine therapy for treating osteoarthritis
Meta Analysis The Cochrane database of systematic reviews 2005 PubMed
B Chondroitin for osteoarthritis
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
B Efficacy and safety of the combination of glucosamine and chondroitin for knee osteoarthritis: a systematic review and meta-analysis
Meta Analysis Archives of orthopaedic and trauma surgery 2023 PubMed DOI
B Glucosamine, chondroitin sulfate, and the two in combination for painful knee osteoarthritis
Rct The New England journal of medicine 2006 PubMed
B Oral Glucosamine in the Treatment of Temporomandibular Joint Osteoarthritis: A Systematic Review
Systematic Review International journal of molecular sciences 2023 PubMed DOI
B Scientific Opinion on glucosamine and joint health
Regulatory Source EFSA Journal 2009 DOI
B Clinical Efficacy and Safety of Chondroitin Combined with Glucosamine in the Treatment of Knee Osteoarthritis: A Systematic Review and Meta-Analysis
Meta Analysis Computational and mathematical methods in medicine 2022 PubMed DOI
B Combined chondroitin sulfate and glucosamine for painful knee osteoarthritis: a multicentre, randomised, double-blind, non-inferiority trial versus celecoxib
Rct Annals of the rheumatic diseases 2016 PubMed DOI
B Effectiveness and safety of glucosamine and chondroitin for the treatment of osteoarthritis: a meta-analysis of randomized controlled trials
Meta Analysis Journal of orthopaedic surgery and research 2018 PubMed DOI
View all evidence for Glucosamine →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.