🟢 87/100

This product is generally safe

  • Manganese: 14mg is 1.3× the Tolerable Upper Intake Level (11mg)
  • Contains proprietary blend — exact ingredient amounts not disclosed
  • 46% of ingredients have research evidence
C Label Compliance Grade

Product Label

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Safety Alerts

⚠️ Manganese: 14mg is 1.3× the Tolerable Upper Intake Level (11mg)
ℹ️ Contains proprietary blend — exact ingredient amounts not disclosed

Label Data

2 Capsule(s) Serving Size
30 Servings
Other Combinations Product Type
46% Evidence Coverage

Supplement Facts — Evidence Check

📊 Market median: 1000.0mg (1115 products) 📚 22 studies (Tier A: 0, B: 9)
This product: 230mg
📊 Market median: 600.0mg (79 products) 📚 24 studies (Tier A: 0, B: 6)
This product: 500mg
MSM
280 mg
📊 Market median: 1000.0mg (2 products)
This product: 280mg
Vitamin C
128 mg (210% DV)
Vitamin C
34 mg (60% DV)
Calcium
46 mg (6% DV)
15 mg (4% DV)
📊 Market median: 4002.0mg (1 products) 📚 20 studies (Tier A: 0, B: 2)
This product: 15mg
36 mg (10% DV)
📊 Market median: 4002.0mg (1 products) 📚 20 studies (Tier A: 0, B: 2)
This product: 36mg
4 mg (30% DV)
✅ Within RDA (0.4× RDA of 11 mg) 📚 258 studies (Tier A: 6, B: 134)
RDA 11mg This product: 4mg UL 40mg
14 mg (700% DV)
⚠️ Exceeds Tolerable Upper Intake Level by 1.3× (UL: 11 mg) 📚 8 studies — no high-quality reviews
RDA 2.3mg This product: 14mg UL 11mg
Proprietary Blend
162 mg

Other Ingredients

Vegetable Capsule

Label Claims — Verification

All Other
Structure/Function
All Other (100% of products) Structure/Function (89% of products) Nutrient (16% of products)

Target Groups

Adult (18 - 50 Years) Gluten Free

Product Information

📋 Directions for Use

Dosage: Two capsules two times a day, or as directed. Do not take if allergic to aspirin.

⚠️ Warnings & Precautions

Do not take if allergic to aspirin.

🧪 Formulation Notes

Gluten free Non GMO No fillers 3x tested

Additional Information

Supports the joints' ability to increase mobility, lubrication, elasticity, flexibility and strength while repairing ligaments, tendons and cartilage.

Gluten free Non GMO

Made in USA

2 Please recycle

Premium quality

Est. 1980

Product Details

UPC / SKU 8 98175 00161 4
DSLD Entry Date 2019-04-25
Product Type Other Combinations
Form Capsule
DSLD ID 200488
Data Updated 2026-04-11

Research Evidence

39 Research Sources
50 Avg Quality Score
20 Rct
9 Meta Analysis
4 Clinical Trial
3 Systematic Review
1 Regulatory Source
1 Openfda Safety
B Interventions for the management of temporomandibular joint osteoarthritis
Systematic Review The Cochrane database of systematic reviews 2012
B Glucosamine therapy for treating osteoarthritis
Meta Analysis The Cochrane database of systematic reviews 2005
B Chondroitin for osteoarthritis
Meta Analysis The Cochrane database of systematic reviews 2015
B Efficacy and safety of the combination of glucosamine and chondroitin for knee osteoarthritis: a systematic review and meta-analysis
Meta Analysis Archives of orthopaedic and trauma surgery 2023
B Glucosamine, chondroitin sulfate, and the two in combination for painful knee osteoarthritis
Rct The New England journal of medicine 2006
B Oral Glucosamine in the Treatment of Temporomandibular Joint Osteoarthritis: A Systematic Review
Systematic Review International journal of molecular sciences 2023
B Scientific Opinion on glucosamine and joint health
Regulatory Source EFSA Journal 2009
B Clinical Efficacy and Safety of Chondroitin Combined with Glucosamine in the Treatment of Knee Osteoarthritis: A Systematic Review and Meta-Analysis
Meta Analysis Computational and mathematical methods in medicine 2022
B Combined chondroitin sulfate and glucosamine for painful knee osteoarthritis: a multicentre, randomised, double-blind, non-inferiority trial versus celecoxib
Rct Annals of the rheumatic diseases 2016
B Effectiveness and safety of glucosamine and chondroitin for the treatment of osteoarthritis: a meta-analysis of randomized controlled trials
Meta Analysis Journal of orthopaedic surgery and research 2018
View all evidence for Glucosamine →

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