🟢 90/100

This product looks safe

  • Contains proprietary blend — exact ingredient amounts not disclosed
  • 17% of ingredients have research evidence
B Label Compliance Grade

Product Label

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Safety Alerts

ℹ️ Contains proprietary blend — exact ingredient amounts not disclosed

Label Data

1 Caplet(s) Serving Size
60 Servings
Other Combinations Product Type
17% Evidence Coverage

Supplement Facts — Evidence Check

Vitamin C
60 mg (100% DV)
2 mg (100% DV)
✅ Within RDA (0.9× RDA of 2.3 mg) 📚 8 studies — no high-quality reviews
RDA 2.3mg This product: 2mg UL 11mg
Sodium
49 mg (2% DV)
📊 Market median: 1000.0mg (1115 products) 📚 22 studies (Tier A: 0, B: 9)
This product: 1500mg
Proprietary Blend
1350 mg
3 mg
📊 Market median: 3.0mg (58 products) 📚 2 studies — no high-quality reviews
This product: 3mg UL 20mg

Other Ingredients

Crospovidone Microcrystalline Cellulose Hydroxypropyl Methylcellulose Polydextrose Titanium Dioxide Silicon Dioxide Magnesium Stearate Talc Maltodextrin fractionated Coconut Oil Caramel Powder Carnauba Wax

Label Claims — Verification

All Other
Structure/Function
All Other (100% of products) Structure/Function (89% of products) Nutrient (16% of products)

Target Groups

Adult (18 - 50 Years) Gluten Free

Product Information

📋 Directions for Use

Directions: Adults, as a dietary supplement, take two caplets daily, preferably with meals. For best results: Take one caplet two times daily.

⚠️ Warnings & Precautions

Warning: Pregnant or nursing women and individuals taking medication(s) or have a health condition should consult their physician prior to using this product.

Keep out of the reach of children.

SAFETY SEALED. DO NOT USE IF PRINTED SEAL UNDER CAP IS CUT, TORN, OR MISSING.

🧪 Formulation Notes

Contains: Crustacean Shellfish (crab, shrimp, lobster, crayfish).

GLUTEN FREE

Additional Information

094 02 0244 135141 517974 TAR645426

Shop Target.com

supports renewal of cartilage* helps maintain the structural integrity of joints* support mobility and flexibility*

Store at 15(0)-30(0)C (59(0)-86(0)F).

FRESHNESS AND POTENCY GUARANTEED THROUGH: 11/15 LOT 000004

Glucosamine Hydrochloride assists in the formation of tendons, ligaments, skin, bones, nails, and muscles. Chondroitin Sulfate helps support healthy connective tissue.*

ID452407

Product Details

UPC / SKU 0 79524 91481 0
DSLD Entry Date 2013-03-25
Product Type Other Combinations
Form Other (e.g. tea bag)
Brand up&up
DSLD ID 20037
Data Updated 2026-04-11

Research Evidence

39 Research Sources
50 Avg Quality Score
20 Rct
9 Meta Analysis
4 Clinical Trial
3 Systematic Review
1 Regulatory Source
1 Openfda Safety
B Interventions for the management of temporomandibular joint osteoarthritis
Systematic Review The Cochrane database of systematic reviews 2012
B Glucosamine therapy for treating osteoarthritis
Meta Analysis The Cochrane database of systematic reviews 2005
B Chondroitin for osteoarthritis
Meta Analysis The Cochrane database of systematic reviews 2015
B Efficacy and safety of the combination of glucosamine and chondroitin for knee osteoarthritis: a systematic review and meta-analysis
Meta Analysis Archives of orthopaedic and trauma surgery 2023
B Glucosamine, chondroitin sulfate, and the two in combination for painful knee osteoarthritis
Rct The New England journal of medicine 2006
B Oral Glucosamine in the Treatment of Temporomandibular Joint Osteoarthritis: A Systematic Review
Systematic Review International journal of molecular sciences 2023
B Scientific Opinion on glucosamine and joint health
Regulatory Source EFSA Journal 2009
B Clinical Efficacy and Safety of Chondroitin Combined with Glucosamine in the Treatment of Knee Osteoarthritis: A Systematic Review and Meta-Analysis
Meta Analysis Computational and mathematical methods in medicine 2022
B Combined chondroitin sulfate and glucosamine for painful knee osteoarthritis: a multicentre, randomised, double-blind, non-inferiority trial versus celecoxib
Rct Annals of the rheumatic diseases 2016
B Effectiveness and safety of glucosamine and chondroitin for the treatment of osteoarthritis: a meta-analysis of randomized controlled trials
Meta Analysis Journal of orthopaedic surgery and research 2018
View all evidence for Glucosamine →

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