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Calm

product on market Tablet or Pill Martin Avenue Pharmacy Safety: 86/100
86/100

This product is generally safe

  • Niacinamide: 100mg is 2.9× the Tolerable Upper Intake Level (35mg)
  • Contains proprietary blend — exact ingredient amounts not disclosed
  • 40% of ingredients have research evidence
C Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · methodology

This profile contains B vitamins and minerals like magnesium and calcium, which are associated with nerve function and muscle relaxation. There is strong evidence supporting these ingredients for general metabolic health, though the specific formulation's evidence coverage is limited. The safety profile is generally high with no significant concerns noted.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Niacinamide: 100mg is 2.9× the Tolerable Upper Intake Level (35mg)

Contains proprietary blend — exact ingredient amounts not disclosed

Label

Product Label

Label for Calm
Open Full PDF View on NIH DSLD →
Details

Label Data

2 Tablet(s)
Serving Size
30
Servings
Other Combinations
Product Type
40%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

50 mg (3333% DV)
41.7× RDA — above typical dose 76 studies (A:0, B:33)
100 mg (500% DV)
Exceeds UL by 2.9× (UL: 35 mg) 196 studies (A:5, B:63)
50 mg (500% DV)
10.0× RDA — above typical dose 2 studies — no high-quality reviews
Calcium
50 mg (5% DV)
100 mg (25% DV)
Within RDA (0.2× RDA) 316 studies (A:8, B:159)
Glutamic Acid
50 mg
Raw Brain Concentrate
500 mg
Passion Flower
200 mg
200 mg
Market median: 300.0mg (214 products) 25 studies (A:0, B:6)
Proprietary Herbal Blend
75 mg

Other Ingredients

Cellulose Vegetable Stearate Silica
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Suggested Usage: As a dietary supplement, adults take 2 tablets daily or as directed by physician.

Warnings & Precautions

Keep out of reach of children.

Tamper resistant package, do not use if outer seal is missing.

Formulation Notes

This product contains NO yeast, wheat gluten, soy protein, milk/dairy, corn, sodium, sugar, starch, artificial coloring, preservatives or flavoring.

Additional Information

"We Make It Better..."

Store in a cool, dry place.

#10028

Natural Relaxing Formula For support of healthy nerve and brain function

QUALITY AND POTENCY GUARANTEED

Metadata

Product Details

DSLD Entry Date2013-02-25
Product TypeOther Combinations
FormTablet or Pill
BrandMartin Avenue Pharmacy
DSLD ID18837
Data Updated2026-04-11
Research

Research Evidence

100
Research Sources
56
Avg Quality
48
Systematic Review
30
Meta Analysis
13
Rct
6
Clinical Trial
1
Cochrane Review
1
Regulatory Source
B Thiamine for prevention and treatment of Wernicke-Korsakoff Syndrome in people who abuse alcohol
Systematic Review The Cochrane database of systematic reviews 2013 PubMed DOI
B Efficacy of B-vitamins and vitamin D therapy in improving depressive and anxiety disorders: a systematic review of randomized controlled trials
Systematic Review Nutritional neuroscience 2023 PubMed DOI
B Effect of thiamine supplementation on glycaemic outcomes in adults with type 2 diabetes: a systematic review and meta-analysis
Meta Analysis BMJ open 2022 PubMed DOI
B Effect of intravenous thiamine administration on critically ill patients: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2024 PubMed DOI
B Effect of adjunctive vitamin C, glucocorticoids, and vitamin B1 on longer-term mortality in adults with sepsis or septic shock: a systematic review and a component network meta-analysis
Systematic Review Intensive care medicine 2022 PubMed DOI
B Effect of Combined Diclofenac and B Vitamins (Thiamine, Pyridoxine, and Cyanocobalamin) for Low Back Pain Management: Systematic Review and Meta-analysis
Meta Analysis Pain medicine (Malden, Mass.) 2020 PubMed DOI
B Thiamine, Ascorbic Acid, and Hydrocortisone As a Metabolic Resuscitation Cocktail in Sepsis: A Meta-Analysis of Randomized Controlled Trials With Trial Sequential Analysis
Meta Analysis Critical care medicine 2021 PubMed DOI
B The effects of thiamine supplementation on patients with heart failure: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Complementary therapies in medicine 2022 PubMed DOI
B Hydrocortisone Combined with Vitamin C and Thiamine in the Treatment of Sepsis/Septic Shock: A Systematic Review with Meta-Analysis and Trial Sequential Analysis
Meta Analysis Clinical and investigative medicine. Medecine clinique et experimentale 2023 PubMed DOI
B Thiamine for Wernicke-Korsakoff Syndrome in people at risk from alcohol abuse
Systematic Review The Cochrane database of systematic reviews 2004 PubMed
View all evidence for Thiamine →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.