St. John's Wort 320 mg

product on market Capsule Nature's Answer 🟢 Safety: 100/100
Brand: Nature's Answer
🟢 100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • Limited research evidence available for ingredients
B Label Compliance Grade

Product Label

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Label Data

1 Capsule(s) Serving Size
Botanical Product Type
0% Evidence Coverage

Supplement Facts — Evidence Check

300 mg
📊 Market median: 300.0mg (240 products) 📚 11 studies — no high-quality reviews
This product: 300mg
20 mg
📊 Market median: 300.0mg (240 products) 📚 11 studies — no high-quality reviews
This product: 20mg

Other Ingredients

Rice Flour Vegetable Cellulose Calcium Silicate

Label Claims — Verification

❓ All Other
❓ Structure/Function
All Other (99% of products) Structure/Function (78% of products) Nutrient (2% of products)

Target Groups

Vegan Vegetarian Adult (18 - 50 Years) Gluten Free

Product Information

📋 Directions for Use

Suggested Use: As a dietary supplement, take one (1) capsule three (3) times a day after meals with a full glass (8 oz) of water.

⚠️ Warnings & Precautions

Caution: This product may cause photosensitivity. Avoid exposure to UV Light (i.e. sunlight, tanning) when using this product.

Warning: Keep out of reach of children.

Do not use with anti-depressants.

Do not use if safety seal is damaged or missing.

If you are pregnant or nursing taking any medications, planning any medical procedure or have a medical condition, consult with your healthcare practitioner before use

🧪 Formulation Notes

Hypericum perforatum

Gluten-Free

Vegan

Additional Information

Store in a cool, dry place.

Gluten Free

Since 1972 Helps Alleviate the Occasional Blue Feeling

18435 Rev. 417

Product Details

UPC / SKU 0 83000 16435 4
DSLD Entry Date 2019-01-07
Product Type Botanical
Form Capsule
Brand Nature's Answer
DSLD ID 184948
Data Updated 2026-04-11

Research Evidence

43 Research Sources
48 Avg Quality Score
16 Meta Analysis
14 Systematic Review
7 Rct
4 Regulatory Source
1 Clinical Trial
1 Openfda Safety
B St John's wort for major depression
Systematic Review The Cochrane database of systematic reviews 2008
PubMed DOI
B Clinical use of Hypericum perforatum (St John's wort) in depression: A meta-analysis
Meta Analysis Journal of affective disorders 2017
PubMed DOI
B A systematic review of St. John's wort for major depressive disorder
Meta Analysis Systematic reviews 2016
PubMed DOI
B St John's wort for depression
Systematic Review The Cochrane database of systematic reviews 2000
PubMed
B Efficacy of Pharmacological Interventions in Milder Depression: A Systematic Review and Meta-Analysis
Meta Analysis Neuropsychopharmacology reports 2025
PubMed DOI
B St John's wort for depression
Meta Analysis The Cochrane database of systematic reviews 2005
PubMed
C St John's wort for depression: meta-analysis of randomised controlled trials
Meta Analysis The British journal of psychiatry : the journal of mental science 2005
PubMed
C The effect of Hypericum perforatum on postmenopausal symptoms and depression: A randomized controlled trial
Rct Complementary therapies in medicine 2019
PubMed DOI
C Hypericum extract versus imipramine or placebo in patients with moderate depression: randomised multicentre study of treatment for eight weeks
Rct BMJ (Clinical research ed.) 1999
PubMed
C Hypericum perforatum as a cognitive enhancer in rodents: A meta-analysis
Meta Analysis Scientific reports 2016
PubMed DOI
View all evidence for St Johns Wort →

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