🟢 100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 33% of ingredients have research evidence
A Label Compliance Grade

Product Label

📸

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Label Data

5.3 Gram(s) Serving Size
30 Servings
Other Combinations Product Type
33% Evidence Coverage

Supplement Facts — Evidence Check

Calories
5 {Calories}
Total Carbohydrates
1 g
Vitamin C
500 mg (833% DV)
30 mg (150% DV)
✅ 2.1× RDA — within safe limits 📚 193 studies (Tier A: 5, B: 63)
RDA 14mg This product: 30mg UL 35mg
100 mg (5000% DV)
📊 76.9× RDA — above typical dose (UL: 100 mg) 📚 113 studies (Tier A: 3, B: 35)
RDA 1.3mg This product: 100mg UL 100mg
1000 mcg (16667% DV)
📊 416.7× RDA — above typical dose 📚 138 studies (Tier A: 1, B: 44)
RDA 0.0024mg This product: 1.0mg
Energy Optimizer Matrix
Blood Flow Support Blend
Antioxidant Support Blend

Other Ingredients

Natural Flavors Citric Acid Beta-Carotene Stevia leaf extract Silica

Label Claims — Verification

Nutrient
All Other
Structure/Function
All Other (99% of products) Structure/Function (83% of products) Nutrient (54% of products)

Target Groups

Adult (18 - 50 Years)

Product Information

📋 Directions for Use

Directions: As a dietary supplement, mix one scoop (5.3 g) with 6-8 fl oz of cold water or your favorite beverage. Take 1-2 servings per day.

⚠️ Warnings & Precautions

WARNING: Consult your physician prior to using this product if you are pregnant, nursing, taking medication, or have a medical condition.

KEEP OUT OF REACH OF CHILDREN.

🧪 Formulation Notes

Vitamin Support-Essential for energy production from B-vitamins, including niacin and methylcobalamin, the body's active form of B-12.* Vitamins B-6 and B-12 function in macronutrient and energy metabolism and are involved in red blood cell synthesis, which provides key components to cells for energy production.* Also provides vitamin C to help protect cells from the damaging effects of free radicals.* Energy Optimizer-Features premium ingredients that help fuel cells and promote energy production.* Creatine helps muscles make and circulate ATP.* Beta-alanine is clinically shown to increase levels of carnosine, a key factor in controlling muscle fatigue.* Glutamine supports protein synthesis and plays an important role in muscle cell hydration.* Carnitine is essential for transforming fatty acids to energy and helps fuel muscles.* CoQ-10 is a powerful antioxidant that is involved in the cellular energy process.* Blood Flow Support-Contains L-arginine, an important amino acid that supports the production of nitric oxide, which helps maintain blood vessel tone and fuel muscle cells.* Also contains MegaNatural(R)-BP(TM) that supports healthy blood circulation and blood pressure levels.* Antioxidant Support-Includes powerful nutrients that enhance metabolism function and provide antioxidant support against free radicals.* Glutathione is a potent antioxidant that supports the activity of the antioxidants vitamin C and E and also supports normal immune system function.*

Additional Information

DEVELOPED WITH AND ENDORSED BY GNC MEDICAL ADVISORY BOARD ADVANCED KNOWLEDGE FOR BETTER HEALTH The GNC Medical Advisory Board utilizes their in-depth medical knowledge and experience to aid in the creation and ongoing development of GNC products, helping GNC stay on the forefront of product innovation and delivering on our commitment to helping you LIVE WELL.

E9641501

This multi-action, stimulant-free formula is designed to fuel cellular energy, maximize blood flow and promote metabolism function.*

Store in a cool, dry place.

NOTICE: Significant product settling may occur.

M(TM) MegaNatural(R)-BP

Setria(TM) The Power To Protect(TM)

NATURAL FLAVORS

PHYSICIAN FORMULATED NUTRITION SOLUTIONS Features premium, clinically studied ingredients & key nutrients that support stimulant-free energy production* Fuels cellular energy & combats a key marker of muscle fatigue with clinically studied beta-alanine* Facilitates the metabolism of fatty acids into energy*

PHYSICIAN ENDORSED

CODE 714812 HNG

Product Details

UPC / SKU 0 48107 11943 0
DSLD Entry Date 2013-02-25
Product Type Other Combinations
Form Powder
DSLD ID 18461
Data Updated 2026-04-11

Research Evidence

371 Research Sources
54 Avg Quality Score
148 Meta Analysis
82 Systematic Review
71 Rct
62 Clinical Trial
2 Regulatory Source
1 Cochrane Review
1 Narrative Review
1 Other
1 Openfda Safety
A Vitamin C supplementation in pregnancy
Meta Analysis The Cochrane database of systematic reviews 2015
A Vitamin C supplementation for the primary prevention of cardiovascular disease
Systematic Review The Cochrane database of systematic reviews 2017
A Vitamin C for preventing and treating the common cold
Meta Analysis The Cochrane database of systematic reviews 2013
A Vitamin C for preventing and treating pneumonia
Meta Analysis The Cochrane database of systematic reviews 2013
A Vitamin E supplementation in pregnancy
Meta Analysis The Cochrane database of systematic reviews 2015
A Vitamin C supplementation for prevention and treatment of pneumonia
Meta Analysis The Cochrane database of systematic reviews 2020
A Vitamin C supplementation for prevention and treatment of pneumonia
Systematic Review The Cochrane database of systematic reviews 2021
A Nutritional interventions for preventing and treating pressure ulcers
Meta Analysis The Cochrane database of systematic reviews 2024
A Does Vitamin C Supplementation Provide a Protective Effect in Periodontal Health? A Systematic Review and Meta-Analysis
Meta Analysis International journal of molecular sciences 2024
A Circulating vitamin C concentration and risk of cancers: a Mendelian randomization study
Meta Analysis BMC medicine 2021
View all evidence for Vitamin C →

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