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Calcium Magnesium Zinc

product on market Tablet or Pill The Vitamin Shoppe Safety: 94/100
94/100

This product looks safe

  • Magnesium: 500mg is 1.4× the Tolerable Upper Intake Level (350mg)
  • 67% of ingredients have research evidence
C Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · methodology

Calcium, magnesium, and vitamin D have strong evidence for supporting bone health and mineral density. Zinc is moderately supported for immune function, while betaine HCl aids digestion. The overall evidence coverage for this specific combination is limited.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Magnesium: 500mg is 1.4× the Tolerable Upper Intake Level (350mg)

Label

Product Label

Label for Calcium Magnesium Zinc
Open Full PDF View on NIH DSLD →
Details

Label Data

2 Tablet(s)
Serving Size
150
Servings
Other Combinations
Product Type
67%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

5 mcg (25% DV)
Within RDA (0.3× RDA) 608 studies (A:16, B:251)
Calcium
1000 mg (80% DV)
500 mg (120% DV)
Exceeds UL by 1.4× (UL: 350 mg) 316 studies (A:8, B:159)
25 mg (230% DV)
2.3× RDA — within safe limits 263 studies (A:6, B:134)
100 mg
Market median: 496.0mg (192 products) 20 studies — no high-quality reviews
Market median: 4002.0mg (1 products) 21 studies (A:0, B:2)

Other Ingredients

Stearic Acid Croscarmellose Sodium Aqueous Coating Microcrystalline Cellulose Magnesium Stearate Silicon Dioxide Hydroxypropylcellulose Titanium Dioxide
Claims

Label Claims — Verification

Unverified Nutrient
Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Directions: Take two (2) tablets daily, preferably with meals.

Warnings & Precautions

Warning: Consult your healthcare provider prior to use if you are pregnant, nursing, taking any medication or have any medical conditions.

Keep out of reach of children.

Tamper evident Do not use if outer seal is broken or missing.

Formulation Notes

2:1 Calcium to Magnesium ratio

Gluten free Dairy free Soy free Nut free

Does not contain: Gluten, Sugar, Salt, Preservatives, Artificial Colors or Flavors.

Additional Information

Mineral

Bones Teeth

Store in a cool, dry place.

Visit www.vitaminshoppe.com or call 1-800-223-1216 for more information and to reorder.

Learn more at vsquality.net

Item No. VS-1453 1048572 ES 37

Metadata

Product Details

UPC / SKU7 66536 01453 8
DSLD Entry Date2019-02-25
Product TypeOther Combinations
FormTablet or Pill
BrandThe Vitamin Shoppe
DSLD ID184259
Data Updated2026-04-11
Research

Research Evidence

849
Research Sources
56
Avg Quality
450
Meta Analysis
152
Rct
137
Systematic Review
73
Clinical Trial
11
Regulatory Source
7
Other
7
Guideline
3
Openfda Safety
2
Cochrane Review
2
Observational
A Phosphate binders for preventing and treating chronic kidney disease-mineral and bone disorder (CKD-MBD)
Meta Analysis The Cochrane database of systematic reviews 2018 PubMed DOI
A Calcium supplementation (other than for preventing or treating hypertension) for improving pregnancy and infant outcomes
Meta Analysis The Cochrane database of systematic reviews 2024 PubMed DOI
A Calcium supplementation (other than for preventing or treating hypertension) for improving pregnancy and infant outcomes
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
A Vitamin and mineral supplementation for maintaining cognitive function in cognitively healthy people in mid and late life
Meta Analysis The Cochrane database of systematic reviews 2018 PubMed DOI
A Calcium supplementation during pregnancy for preventing hypertensive disorders and related problems
Meta Analysis The Cochrane database of systematic reviews 2025 PubMed DOI
A Dietary calcium supplementation for preventing colorectal cancer and adenomatous polyps
Systematic Review The Cochrane database of systematic reviews 2008 PubMed DOI
A Calcium and vitamin D for increasing bone mineral density in premenopausal women
Systematic Review The Cochrane database of systematic reviews 2023 PubMed DOI
A Dietary sodium, sodium-to-potassium ratio, and risk of stroke: A systematic review and nonlinear dose-response meta-analysis
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2019 PubMed DOI
A The association between circulating magnesium and clinically relevant outcomes in patients with chronic kidney disease: A systematic review and meta-analysis
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2021 PubMed DOI
A Calcium channel blockers versus other classes of drugs for hypertension
Systematic Review The Cochrane database of systematic reviews 2021 PubMed DOI
View all evidence for Electrolytes →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.