🟢 100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 100% of ingredients have research evidence
A Label Compliance Grade

Product Label

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Label Data

1 Vegetarian Capsule(s) Serving Size
Vitamin Product Type
100% Evidence Coverage

Supplement Facts — Evidence Check

50 mg (3846% DV)
📊 38.5× RDA — above typical dose 📚 12 studies (Tier A: 0, B: 1)
RDA 1.3mg This product: 50mg

Other Ingredients

Microcrystalline Cellulose Vegetarian Capsule Farm Fresh Factors Magnesium Stearate Stearic Acid

Label Claims — Verification

Nutrient
All Other
Structure/Function
All Other (99% of products) Structure/Function (85% of products) Nutrient (48% of products) No Claim (1% of products)

Target Groups

Vegan Vegetarian Adult (18 - 50 Years) Gluten Free Dairy Free Sugar Free

Product Information

📋 Directions for Use

Suggested usage: 1 capsule per day or as directed by a health professional.

⚠️ Warnings & Precautions

Cautions: As with an supplement, consult your health professional before use if you are pregnant, breastfeeding, or trying to conceive, or if you are taking medication, have a medical condition, or anticipate a surgery.

Keep out of the reach of children.

Sealed for your protection. Do not use if seal is broken.

🧪 Formulation Notes

Riboflavin (Vitamin B2) plays a key role in the activation and conversion of other B vitamins as well as in red blood cell synthesis, fat and glucose metabolism, and the production and regulation of specific biochemicals. Riboflavin 5'-phosphate is the coenzyme form of vitamin B2. Taking riboflavin 5'-phosphate allows for greater absorption and bioavailability that non-coenzyme forms.

Contains no artificial colors, preservatives, or sweeteners; no dairy, starch, sugar, wheat, gluten, yeast, soy, egg, fish, shellfish, animal products, salt, tree nuts, or GMOs.

Suitable for vegetarians/vegans.

B2

Additional Information

isura Non-GMO Mass Spec Documentation Lab Tested

Manufactured by Natural Factors to ensure safety and potency in accordance with Good Manufacturing Practices (GMP) of the FDA and Health Canada.

For freshness, store in a cool, dry place.

Product of Canada Purity & Potency Guaranteed Recyclable container and label.

The most metabolically active form

R0

This product has passed the most rigorous testing in the world for contaminants and quality. isura.ca

What does coenzymated mean? In order for B vitamins to be utilized effectively by the body, they must be converted into their metabolically active coenzyme forms. For example, the coenzyme form of riboflavin is riboflavin 5'-phosphate. A coenzyme is a naturally occurring compound that partners with specific enzymes in order to help promote a number of beneficial metabolic reactions in the body. Without the coenzyme, the enzyme cannot promote the biochemical reaction that is responsible for our survival. This dual cooperation between coenzyme and enzyme is a process called coenzymated. Taking B vitamins already in their coenzymated forms allows the body to use them directly. Thus, the amount that is needed by the body is less in order to achieve the same benefits. Biocoenzymated takes it one step further.

The synergy between the phytochemicals found in these plant extracts and the coenzyme B vitamin optimizes absorption. The results? Biocoenzymated delivers the most metabolically active nutrients to your cells to utilize most effectively. Feel the difference.

Product Details

UPC / SKU 0 68958 01249 0
DSLD Entry Date 2018-09-21
Product Type Vitamin
Form Capsule
DSLD ID 180911
Data Updated 2026-04-11

Research Evidence

22 Research Sources
49 Avg Quality Score
8 Rct
4 Meta Analysis
4 Clinical Trial
3 Systematic Review
1 Cochrane Review
1 Regulatory Source
B Effect of vitamin B2, vitamin C, vitamin D, vitamin E and folic acid in adults with essential hypertension: a systematic review and network meta-analysis
Systematic Review BMJ open 2024
B Effect of Vitamin B2 supplementation on migraine prophylaxis: a systematic review and meta-analysis
Meta Analysis Nutritional neuroscience 2022
B Supplementary vitamin E, selenium, cysteine and riboflavin for preventing kwashiorkor in preschool children in developing countries
Systematic Review The Cochrane database of systematic reviews 2010
B Riboflavin supplements for blood pressure lowering in adults.
Cochrane Review The Cochrane database of systematic reviews
B Associations of dietary vitamin B1, vitamin B2, vitamin B6, and vitamin B12 with the risk of depression: a systematic review and meta-analysis
Meta Analysis Nutrition reviews 2022
C Prophylaxis of migraine headaches with riboflavin: A systematic review
Systematic Review Journal of clinical pharmacy and therapeutics 2017
C Medium-dose riboflavin as a prophylactic agent in children with migraine: a preliminary placebo-controlled, randomised, double-blind, cross-over trial
Rct Cephalalgia : an international journal of headache 2010
C The efficacy of 2 different phakic intraocular lens implant in keratoconus as an isolated procedure or combined with collagen crosslinking and intra-stromal corneal ring segments: a systematic review and meta-analysis
Meta Analysis International ophthalmology 2023
C Epithelium-off photochemical corneal collagen cross-linkage using riboflavin and ultraviolet a for keratoconus and keratectasia: a systematic review and meta-analysis
Meta Analysis The ocular surface 2014
C Improvement of migraine symptoms with a proprietary supplement containing riboflavin, magnesium and Q10: a randomized, placebo-controlled, double-blind, multicenter trial
Rct The journal of headache and pain 2015
View all evidence for Riboflavin →

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