🟢 100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 50% of ingredients have research evidence
A Label Compliance Grade

Product Label

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Label Data

2 Caplet(s) Serving Size
85 Servings
Other Combinations Product Type
50% Evidence Coverage

Supplement Facts — Evidence Check

Sodium
75 mg (3% DV)
📊 Market median: 1000.0mg (1115 products) 📚 22 studies (Tier A: 0, B: 9)
This product: 1.5mg
📊 Market median: 600.0mg (79 products) 📚 24 studies (Tier A: 0, B: 6)
This product: 800mg
📊 Market median: 1000.0mg (2 products)
This product: 750mg

Other Ingredients

Glucosamine Hydrochloride Sodium Chondroitin Sulfate Methylsulfonylmethane Hypromellose Color added Silicon Dioxide Magnesium Stearate Inulin

Label Claims — Verification

All Other
Structure/Function
All Other (100% of products) Structure/Function (89% of products) Nutrient (16% of products)

Target Groups

Adult (18 - 50 Years) Gluten Free

Product Information

📋 Directions for Use

Two caplets per day

Suggested use: Take two caplets daily, with food. For easier swallowing, take with water before and during ingestion. Caplets can be taken together or at different times during the day. Take 4-6 weeks to see results.

⚠️ Warnings & Precautions

Store in a cool, dry place, out of reach of children.

Do not use if imprinted seal under cap is broken or missing.

Caution: If you are pregnant or nursing, or allergic to shellfish, consult your health care professional before taking this product.

Caution: If you are pregnant or nursing, or allergic to shellfish, consult your health care professional before taking this product. Contains: Shellfish (Shrimp & Crab).

🧪 Formulation Notes

Glucosamine 1500 mg Chondroitin 800 mg MSM 750 mg

Color derived from natural source - No synthetic dyes No artificial flavors No preservatives No yeast Gluten free

Contains: Shellfish (Shrimp & Crab).

Additional Information

List No. 4128 L202 Cat. A054 5A009 ITEM # 864044

Triple strength

For comfort, mobility & flexibility

Keep bottle tightly closed. Store in a cool, dry place, out of reach of children.

Tableted and Quality Tested in the U.S.A. TripleFlex caplets are made to Nature Made’s guaranteed purity and potency standards.

Product Details

UPC / SKU 0 31604 04128 1
DSLD Entry Date 2018-08-31
Product Type Other Combinations
Form Other (e.g. tea bag)
Brand Nature Made
DSLD ID 180260
Data Updated 2026-04-11

Research Evidence

39 Research Sources
50 Avg Quality Score
20 Rct
9 Meta Analysis
4 Clinical Trial
3 Systematic Review
1 Regulatory Source
1 Openfda Safety
B Interventions for the management of temporomandibular joint osteoarthritis
Systematic Review The Cochrane database of systematic reviews 2012
B Glucosamine therapy for treating osteoarthritis
Meta Analysis The Cochrane database of systematic reviews 2005
B Chondroitin for osteoarthritis
Meta Analysis The Cochrane database of systematic reviews 2015
B Efficacy and safety of the combination of glucosamine and chondroitin for knee osteoarthritis: a systematic review and meta-analysis
Meta Analysis Archives of orthopaedic and trauma surgery 2023
B Glucosamine, chondroitin sulfate, and the two in combination for painful knee osteoarthritis
Rct The New England journal of medicine 2006
B Oral Glucosamine in the Treatment of Temporomandibular Joint Osteoarthritis: A Systematic Review
Systematic Review International journal of molecular sciences 2023
B Scientific Opinion on glucosamine and joint health
Regulatory Source EFSA Journal 2009
B Clinical Efficacy and Safety of Chondroitin Combined with Glucosamine in the Treatment of Knee Osteoarthritis: A Systematic Review and Meta-Analysis
Meta Analysis Computational and mathematical methods in medicine 2022
B Combined chondroitin sulfate and glucosamine for painful knee osteoarthritis: a multicentre, randomised, double-blind, non-inferiority trial versus celecoxib
Rct Annals of the rheumatic diseases 2016
B Effectiveness and safety of glucosamine and chondroitin for the treatment of osteoarthritis: a meta-analysis of randomized controlled trials
Meta Analysis Journal of orthopaedic surgery and research 2018
View all evidence for Glucosamine →

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