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TripleFlex

product on market Other (e.g. tea bag) Nature Made Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 50% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · methodology

Glucosamine, chondroitin, and MSM are commonly used to support joint health and cartilage function. Research provides moderate evidence that these ingredients may reduce joint discomfort, though results vary across studies. The overall evidence coverage for this specific combination remains limited.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for TripleFlex
Open Full PDF View on NIH DSLD →
Details

Label Data

2 Caplet(s)
Serving Size
85
Servings
Other Combinations
Product Type
50%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Sodium
75 mg (3% DV)
Market median: 1000.0mg (1115 products) 24 studies (A:0, B:9)
Market median: 600.0mg (79 products) 25 studies (A:0, B:6)
Market median: 1000.0mg (2 products)

Other Ingredients

Glucosamine Hydrochloride Sodium Chondroitin Sulfate Methylsulfonylmethane Hypromellose Color added Silicon Dioxide Magnesium Stearate Inulin
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Two caplets per day

Suggested use: Take two caplets daily, with food. For easier swallowing, take with water before and during ingestion. Caplets can be taken together or at different times during the day. Take 4-6 weeks to see results.

Warnings & Precautions

Store in a cool, dry place, out of reach of children.

Do not use if imprinted seal under cap is broken or missing.

Caution: If you are pregnant or nursing, or allergic to shellfish, consult your health care professional before taking this product.

Caution: If you are pregnant or nursing, or allergic to shellfish, consult your health care professional before taking this product. Contains: Shellfish (Shrimp & Crab).

Formulation Notes

Glucosamine 1500 mg Chondroitin 800 mg MSM 750 mg

Color derived from natural source - No synthetic dyes No artificial flavors No preservatives No yeast Gluten free

Contains: Shellfish (Shrimp & Crab).

Additional Information

List No. 4128 L202 Cat. A054 5A009 ITEM # 864044

Triple strength

For comfort, mobility & flexibility

Keep bottle tightly closed. Store in a cool, dry place, out of reach of children.

Tableted and Quality Tested in the U.S.A. TripleFlex caplets are made to Nature Made’s guaranteed purity and potency standards.

Metadata

Product Details

UPC / SKU0 31604 04128 1
DSLD Entry Date2018-08-31
Product TypeOther Combinations
FormOther (e.g. tea bag)
DSLD ID180260
Data Updated2026-04-11
Research

Research Evidence

39
Research Sources
50
Avg Quality
20
Rct
9
Meta Analysis
4
Clinical Trial
3
Systematic Review
1
Regulatory Source
1
Openfda Safety
B Interventions for the management of temporomandibular joint osteoarthritis
Systematic Review The Cochrane database of systematic reviews 2012 PubMed DOI
B Glucosamine therapy for treating osteoarthritis
Meta Analysis The Cochrane database of systematic reviews 2005 PubMed
B Chondroitin for osteoarthritis
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
B Efficacy and safety of the combination of glucosamine and chondroitin for knee osteoarthritis: a systematic review and meta-analysis
Meta Analysis Archives of orthopaedic and trauma surgery 2023 PubMed DOI
B Glucosamine, chondroitin sulfate, and the two in combination for painful knee osteoarthritis
Rct The New England journal of medicine 2006 PubMed
B Oral Glucosamine in the Treatment of Temporomandibular Joint Osteoarthritis: A Systematic Review
Systematic Review International journal of molecular sciences 2023 PubMed DOI
B Scientific Opinion on glucosamine and joint health
Regulatory Source EFSA Journal 2009 DOI
B Clinical Efficacy and Safety of Chondroitin Combined with Glucosamine in the Treatment of Knee Osteoarthritis: A Systematic Review and Meta-Analysis
Meta Analysis Computational and mathematical methods in medicine 2022 PubMed DOI
B Combined chondroitin sulfate and glucosamine for painful knee osteoarthritis: a multicentre, randomised, double-blind, non-inferiority trial versus celecoxib
Rct Annals of the rheumatic diseases 2016 PubMed DOI
B Effectiveness and safety of glucosamine and chondroitin for the treatment of osteoarthritis: a meta-analysis of randomized controlled trials
Meta Analysis Journal of orthopaedic surgery and research 2018 PubMed DOI
View all evidence for Glucosamine →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.