🟢 100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 33% of ingredients have research evidence
A Label Compliance Grade

Product Label

📸

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Label Data

1 Softgel(s) Serving Size
Other Combinations Product Type
33% Evidence Coverage

Supplement Facts — Evidence Check

Calories
5 Calorie(s)
0.5 mg (29% DV)
✅ Within RDA (0.4× RDA of 1.3 mg) 📚 12 studies (Tier A: 0, B: 1)
RDA 1.3mg This product: 0.5mg
📊 Market median: 200.0mg (198 products) 📚 6 studies — no high-quality reviews
This product: 200mg

Other Ingredients

Medium Chain Triglycerides Gelatin Glycerin Soy Lecithin Water Soybean Oil yellow Beeswax

Label Claims — Verification

All Other
Structure/Function
All Other (98% of products) Structure/Function (87% of products) Nutrient (16% of products)

Target Groups

Adult (18 - 50 Years) Gluten Free

Product Information

📋 Directions for Use

Suggested use: Take 1 softgel daily on an empty stomach. For easier swallowing, take with water before and during ingestion.

⚠️ Warnings & Precautions

Store in a cool, dry place, out of the reach of children.

Do not use if imprinted seal under cap is broken or missing.

Caution: Do not take if pregnant or breastfeeding. Persons with diabetes or who are glucoseintolerant should check with their healthcare professional before use.

Contains: Soy.

🧪 Formulation Notes

No color added No artificial flavors No preservatives No yeast or starch Gluten free

Contains: Soy.

Additional Information

List No. 2947 L201 Cat. A708 5J030

Antioxidant activity that helps neutralize free radicals

Keep bottle tightly closed. Store in a cool, dry place, out of the reach of children.

Alpha Lipoic Acid softgels are made to Nature Made’s guaranteed purity and potency standards.

Product Details

UPC / SKU 0 31604 02947 0
DSLD Entry Date 2018-08-31
Product Type Other Combinations
Form Softgel Capsule
Brand Nature Made
DSLD ID 179979
Data Updated 2026-04-11

Research Evidence

21 Research Sources
52 Avg Quality Score
13 Rct
4 Meta Analysis
2 Systematic Review
2 Clinical Trial
A Alpha-lipoic acid for diabetic peripheral neuropathy
Systematic Review The Cochrane database of systematic reviews 2024
B Efficacy and Safety of the Combination of Palmitoylethanolamide, Superoxide Dismutase, Alpha Lipoic Acid, Vitamins B12, B1, B6, E, Mg, Zn and Nicotinamide for 6 Months in People with Diabetic Neuropathy
Rct Nutrients 2024
B Alpha Lipoic Acid Supplementation and Iron Homeostasis: A Comprehensive Systematic Review and Meta-Analysis of Randomized Controlled Clinical Trials
Meta Analysis International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition 2024
B Effectiveness of alpha-lipoic acid in patients with neuropathic pain associated with type I and type II diabetes mellitus: A systematic review and meta-analysis
Meta Analysis Medicine 2023
C The effects of alpha-lipoic acid supplementation on glucose control and lipid profiles among patients with metabolic diseases: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Metabolism: clinical and experimental 2018
C A systematic review and meta-analysis of α-lipoic acid in the treatment of diabetic peripheral neuropathy
Meta Analysis European journal of endocrinology 2012
C Oral Alpha Lipoic Acid Treatment for Symptomatic Diabetic Peripheral Neuropathy: A Randomized Double-Blinded Placebo-Controlled Study
Rct Endocrine, metabolic & immune disorders drug targets 2020
C A randomized, double-blind, placebo controlled study to evaluate the effect of alpha-lipoic acid on inhibition of ADP-and collagen-induced platelet aggregation ex vivo in diabetic neuropathy patients on gabapentin or pregabalin
Rct Journal of postgraduate medicine 2024
C Ranking Alpha Lipoic Acid and Gamma Linolenic Acid in Terms of Efficacy and Safety in the Management of Adults With Diabetic Peripheral Neuropathy: A Systematic Review and Network Meta-analysis
Systematic Review Canadian journal of diabetes 2024
C Effect analysis of tanshinone IIA sulfonate sodium combined with a-lipoic acid in patients with diabetes peripheral neuropathy.
Rct Pakistan journal of pharmaceutical sciences
View all evidence for Alpha Lipoic Acid →

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