Home/ Supplements/ Niacin/ Hybrid N.O.

Hybrid N.O.

product on market Capsule MusclePharm Safety: 95/100
95/100

This product looks safe

  • Niacin: 50mg is 1.4× the Tolerable Upper Intake Level (35mg)
  • 25% of ingredients have research evidence
C Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · methodology

Citrulline malate and agmatine sulfate have moderate evidence for supporting nitric oxide production and blood flow. Niacin and calcium contribute to energy metabolism and muscle function, while Glycocarn is a proprietary blend with limited independent research. The overall profile is supported by a high safety score.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Niacin: 50mg is 1.4× the Tolerable Upper Intake Level (35mg)

Label

Product Label

Label for Hybrid N.O.
Open Full PDF View on NIH DSLD →
Details

Label Data

4 Capsule(s)
Serving Size
20
Servings
Other Combinations
Product Type
25%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

50 mg (2500% DV)
Exceeds UL by 1.4× (UL: 35 mg) 196 studies (A:5, B:63)
Calcium
100 mg (10% DV)
Agmatine Sulfate
750 mg
Market median: 2000.0mg (275 products)
Glycocarn(R)
500 mg
Beet root extract
200 mg
Market median: 333.0mg (166 products) 9 studies (A:0, B:2)
Rutaecarpine 98%
10 mg

Other Ingredients

Gelatin Magnesium Stearate Microcrystalline Cellulose
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

DIRECTIONS: Consume 4 capsules prior to workout. For optimal results, take 30 minutes before your workout.

Warnings & Precautions

ALLERGEN WARNING: This product was produced in a facility that may also process ingredients containing milk, egg, soybeans, shellfish, fish, tree nuts, and peanuts.

WARNING: Do not exceed the recommended daily dose.

Do not use if you are pregnant, expect to become pregnant or are nursing.

This product is only intended for use by healthy adults over 18 years of age. Do not take this product if you are at risk or are being treated for any medical condition.

KEEP OUT OF REACH OF CHILDREN.

Additional Information

HYBRID SERIES

GET SWOLE. LIVE SWOLE. NITRIC OXIDE AMPLIFIER -DRAMATICALLY ENHANCE MUSCLE PUMPS -INCREASE MUSCLE FULLNESS & VASCULARITY -MAXIMIZE VASODILATATION

STORAGE CONDITIONS: Store in a cool dry place.

HealthScience and is manufactured under USA production patent 6703042 and Worldwide production patent EP1202956

GLYCOCARN(R) USP

BANNED-SUBSTANCE FREE CERTIFICATIONS

{check} INFORMED CHOICE

ADVANCED NITRIC OXIDE AMPLIFYING SYSTEM: YOUR PUMPS WILL EXPLODE. Only the MP sports science team brings you this meticulous formulation of precisely-engineered nutrients. High intensity athletes: get ready for massive pumps, muscle fullness, vascularity, enhanced size and strength, and reduced fatigue.

{QR code f} FACEBOOK.COM/MUSCLEPHARM

MADE IN USA

Dom v1.1 20120126

Metadata

Product Details

UPC / SKU7 36211 05107 3
DSLD Entry Date2013-02-25
Product TypeOther Combinations
FormCapsule
BrandMusclePharm
DSLD ID17960
Data Updated2026-04-11
Research

Research Evidence

241
Research Sources
55
Avg Quality
113
Meta Analysis
75
Systematic Review
32
Rct
11
Clinical Trial
3
Other
3
Regulatory Source
1
Cochrane Review
1
Narrative Review
1
Openfda Safety
A Niacin for primary and secondary prevention of cardiovascular events
Meta Analysis The Cochrane database of systematic reviews 2017 PubMed DOI
A Use of high potency statins and rates of admission for acute kidney injury: multicenter, retrospective observational analysis of administrative databases
Meta Analysis BMJ (Clinical research ed.) 2013 PubMed DOI
A Effect on cardiovascular risk of high density lipoprotein targeted drug treatments niacin, fibrates, and CETP inhibitors: meta-analysis of randomised controlled trials including 117,411 patients
Meta Analysis BMJ (Clinical research ed.) 2014 PubMed DOI
A A terminal metabolite of niacin promotes vascular inflammation and contributes to cardiovascular disease risk
Meta Analysis Nature medicine 2024 PubMed DOI
A Meta-analysis and imputation refines the association of 15q25 with smoking quantity
Meta Analysis Nature genetics 2010 PubMed DOI
A Genome-wide meta-analyses identify multiple loci associated with smoking behavior
Meta Analysis Nature genetics 2010 PubMed DOI
A Antidepressants for smoking cessation
Meta Analysis The Cochrane database of systematic reviews 2014 PubMed DOI
A Topical azelaic acid, salicylic acid, nicotinamide, sulphur, zinc and fruit acid (alpha-hydroxy acid) for acne
Meta Analysis The Cochrane database of systematic reviews 2020 PubMed DOI
B Assessment of the Role of Niacin in Managing Cardiovascular Disease Outcomes: A Systematic Review and Meta-analysis
Meta Analysis JAMA network open 2019 PubMed DOI
B Association Between Lowering LDL-C and Cardiovascular Risk Reduction Among Different Therapeutic Interventions: A Systematic Review and Meta-analysis
Meta Analysis JAMA 2016 PubMed DOI
View all evidence for Niacin →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.