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TripleFlex 50+

product on market Other (e.g. tea bag) Nature Made Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 60% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · methodology

Calcium and vitamin D3 have strong evidence for supporting bone density and health. Glucosamine and chondroitin are commonly used for joint support, though research on their efficacy for joint health is mixed. The overall evidence coverage for this specific combination is limited.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for TripleFlex 50+
Open Full PDF View on NIH DSLD →
Details

Label Data

2 Caplet(s)
Serving Size
60
Servings
Other Combinations
Product Type
60%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

750 IU (188% DV)
1.2× RDA — within safe limits 608 studies (A:16, B:251)
Calcium
200 mg (20% DV)
Sodium
75 mg (3% DV)
Market median: 1000.0mg (1115 products) 24 studies (A:0, B:9)
Market median: 600.0mg (79 products) 25 studies (A:0, B:6)

Other Ingredients

Glucosamine Hydrochloride Sodium Chondroitin Sulfate Calcium Citrate Calcium Carbonate Cellulose Gel Crospovidone Hypromellose Color added Silicon Dioxide Magnesium Stearate Polyethylene Glycol Triethyl Citrate Polysorbate 80 Gelatin Corn Starch Vitamin D3
Claims

Label Claims — Verification

Unverified Nutrient
Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

2 caplets per day

Suggested use: Take two caplets daily. Caplets can be taken either before or with a meal. For easier swallowing, take with water before and during ingestion.

Warnings & Precautions

Store in a cool, dry place, out of reach of children.

Do not use if imprinted seal under cap is broken or missing.

Caution: If you are pregnant or nursing, or have allergies to shellfish, please consult your health care professional before taking this product.

Contains: Shellfish (shrimp and crab).

Formulation Notes

Specially formulated for adult 50+

TripleFlex 50+ provides the body with key nutrients that help support daily maintenance of your joints with: Glucosamine – helps support joint comfort, mobility and flexibility Chondroitin – helps lubricate and cushion the joints Calcium and Vitamin D – Calcium helps build and maintain strong bones and teeth; vitamin D improves calcium absorption, helps support and maintain strong bones, and helps support healthy muscle tissue.

Glucosamine Chondroitin Calcium + vitamin D

Contains: Shellfish (shrimp and crab).

Color derived from natural source - no synthetic dyes No artificial flavors No preservatives No yeast Gluten free

Additional Information

Triple-ingredient Triple-action Triple-benefit Cartilage Synovial fluid Bone Tendon Glucosamine: Basic building block for maintaining joint cartilage and helps to maintain structural integrity of your joints. Beneficial for joint elasticity and flexibility. Helps promote mobility and support. Chondroitin: A naturally occurring nutrient found in the connective tissues, which lubricates and cushions your joints. Calcium + vitamin D: These nutrients are essential for building and maintaining strong bones and teeth. Vitamin D has also been shown to strengthen muscle.

List No. 1467 P201 Cat. A130 1A160

No matter what your age joint discomfort can make you feel older than you really are. TripleFlex lets you live as young as you feel. TripleFlex 50+ from Nature Made helps people over 50 maintain healthy joints with a special formula designed just for them. TripleFlex 50+ works with your body naturally to help support joint comfort, mobility and flexibility.

TripleFlex keeps you living as young as you feel.

Triple strength

Keep bottle tightly closed. Store in a cool, dry place, out of reach of children.

Tableted and Quality tested in the U.S.A.

Metadata

Product Details

UPC / SKU0 31604 01467 4
DSLD Entry Date2018-08-31
Product TypeOther Combinations
FormOther (e.g. tea bag)
DSLD ID179468
Data Updated2026-04-11
Research

Research Evidence

872
Research Sources
53
Avg Quality
309
Meta Analysis
309
Clinical Trial
111
Rct
71
Systematic Review
55
Guideline
4
Cochrane Review
4
Regulatory Source
2
Other
2
Narrative Review
2
Observational
1
Openfda Safety
A Vitamin D and vitamin D analogues for preventing fractures associated with involutional and post-menopausal osteoporosis
Meta Analysis The Cochrane database of systematic reviews 2009 PubMed DOI
A Vitamin D supplementation for prevention of mortality in adults
Meta Analysis The Cochrane database of systematic reviews 2014 PubMed DOI
A Vitamin D and vitamin D analogues for preventing fractures in post-menopausal women and older men
Meta Analysis The Cochrane database of systematic reviews 2014 PubMed DOI
A Vitamin D supplementation for prevention of cancer in adults
Meta Analysis The Cochrane database of systematic reviews 2014 PubMed DOI
A Interventions for preventing falls in older people in care facilities and hospitals
Meta Analysis The Cochrane database of systematic reviews 2018 PubMed DOI
A Drugs for preventing lung cancer in healthy people
Meta Analysis The Cochrane database of systematic reviews 2020 PubMed DOI
A Vitamin D supplementation for prevention of mortality in adults
Meta Analysis The Cochrane database of systematic reviews 2011 PubMed DOI
A High prevalence of vitamin D deficiency in Asia: A systematic review and meta-analysis
Meta Analysis Critical reviews in food science and nutrition 2023 PubMed DOI
A The effect of vitamin D supplementation on depressive symptoms in adults: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Critical reviews in food science and nutrition 2023 PubMed DOI
A Interventions for preventing falls in older people living in the community
Meta Analysis The Cochrane database of systematic reviews 2009 PubMed DOI
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.