🟢 100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 50% of ingredients have research evidence
A Label Compliance Grade

Product Label

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Label Data

2 Caplet(s) Serving Size
60 Servings
Other Combinations Product Type
50% Evidence Coverage

Supplement Facts — Evidence Check

Sodium
75 mg (3% DV)
📊 Market median: 1000.0mg (1115 products) 📚 22 studies (Tier A: 0, B: 9)
This product: 1.5mg
📊 Market median: 600.0mg (79 products) 📚 24 studies (Tier A: 0, B: 6)
This product: 800mg
📊 Market median: 1000.0mg (2 products)
This product: 750mg

Other Ingredients

Glucosamine Hydrochloride Sodium Chondroitin Sulfate Methylsulfonylmethane Hypromellose Color added Silicon Dioxide Magnesium Stearate Inulin

Label Claims — Verification

All Other
Structure/Function
All Other (100% of products) Structure/Function (89% of products) Nutrient (16% of products)

Target Groups

Adult (18 - 50 Years) Gluten Free

Product Information

📋 Directions for Use

2 caplets per day

Suggested use: Take two caplets daily, with food. For easier swallowing, take with water before and during ingestion. Caplets can be taken together or at different times during the day. Take 4-6 weeks to see results.

⚠️ Warnings & Precautions

Store in a cool, dry place, out of reach of children.

Do not use if imprinted seal under cap is broken or missing.

Caution: If you are pregnant or nursing, or allergic to shellfish, consult your health care professional before taking this product.

Caution: If you are pregnant or nursing, or allergic to shellfish, consult your health care professional before taking this product. Contains: Shellfish (shrimp & crab).

🧪 Formulation Notes

Glucosamine 1500 mg Chondroitin 800 mg MSM 750 mg

Contains: Shellfish (shrimp & crab).

Color derived from natural source - No synthetic dyes No artificial flavors No preservatives No yeast Gluten free

Additional Information

Comfort Mobility Flexibility Triple-ingredient Triple-action Triple-benefit Cartilage Synovial fluid Bone Tendon Glucosamine: Helps support joint comfort, mobility, and flexibility. Chondroitin: A naturally occurring nutrient found in connective tissue that helps support joint lubrication and cushioning. MSM: A source of dietary sulfur that is used by the body for building collagen, connective tissue and joint cartilage.

List No. 1431 SP201 Cat. A054 1A160

TripleFlex works with your body naturally to help support long term joint comfort, mobility and flexibility. TripleFlex does this by providing the key nutrients that help support long term continuation of healthy joint.

Chondroitin - Helps support joint lubrication and cushioning that helps maintain joint flexibility MSM - A source of dietary sulfur, a mineral used by the body in collagen, connective tissue and joint cartilage

Triple strength

Keep bottle tightly closed. Store in a cool, dry place, out of reach of children.

Tableted and Quality Tested in the U.S.A.

Product Details

UPC / SKU 0 31604 01431 5
DSLD Entry Date 2018-07-25
Product Type Other Combinations
Form Other (e.g. tea bag)
Brand Nature Made
DSLD ID 179454
Data Updated 2026-04-11

Research Evidence

39 Research Sources
50 Avg Quality Score
20 Rct
9 Meta Analysis
4 Clinical Trial
3 Systematic Review
1 Regulatory Source
1 Openfda Safety
B Interventions for the management of temporomandibular joint osteoarthritis
Systematic Review The Cochrane database of systematic reviews 2012
B Glucosamine therapy for treating osteoarthritis
Meta Analysis The Cochrane database of systematic reviews 2005
B Chondroitin for osteoarthritis
Meta Analysis The Cochrane database of systematic reviews 2015
B Efficacy and safety of the combination of glucosamine and chondroitin for knee osteoarthritis: a systematic review and meta-analysis
Meta Analysis Archives of orthopaedic and trauma surgery 2023
B Glucosamine, chondroitin sulfate, and the two in combination for painful knee osteoarthritis
Rct The New England journal of medicine 2006
B Oral Glucosamine in the Treatment of Temporomandibular Joint Osteoarthritis: A Systematic Review
Systematic Review International journal of molecular sciences 2023
B Scientific Opinion on glucosamine and joint health
Regulatory Source EFSA Journal 2009
B Clinical Efficacy and Safety of Chondroitin Combined with Glucosamine in the Treatment of Knee Osteoarthritis: A Systematic Review and Meta-Analysis
Meta Analysis Computational and mathematical methods in medicine 2022
B Combined chondroitin sulfate and glucosamine for painful knee osteoarthritis: a multicentre, randomised, double-blind, non-inferiority trial versus celecoxib
Rct Annals of the rheumatic diseases 2016
B Effectiveness and safety of glucosamine and chondroitin for the treatment of osteoarthritis: a meta-analysis of randomized controlled trials
Meta Analysis Journal of orthopaedic surgery and research 2018
View all evidence for Glucosamine →

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