🟢 100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 60% of ingredients have research evidence
A Label Compliance Grade

Product Label

📸

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Label Data

2 Caplet(s) Serving Size
60 Servings
Other Combinations Product Type
60% Evidence Coverage

Supplement Facts — Evidence Check

2000 IU (500% DV)
📊 3.3× RDA — above typical dose (UL: 0.1 mg) 📚 604 studies (Tier A: 16, B: 251)
RDA 0.015mg This product: 0.05mg UL 0.1mg
Sodium
75 mg (3% DV)
📊 Market median: 1000.0mg (1115 products) 📚 22 studies (Tier A: 0, B: 9)
This product: 1.5mg
📊 Market median: 600.0mg (79 products) 📚 24 studies (Tier A: 0, B: 6)
This product: 800mg
📊 Market median: 1000.0mg (2 products)
This product: 750mg

Other Ingredients

Glucosamine Hydrochloride Sodium Chondroitin Sulfate Methylsulfonylmethane Hypromellose Color added Silicon Dioxide Magnesium Stearate Glyceryl Behenate Polyethylene Glycol Corn Starch Triethyl Citrate Polysorbate 80 Vitamin D3

Label Claims — Verification

Nutrient
All Other
Structure/Function
All Other (99% of products) Structure/Function (85% of products) Nutrient (70% of products) Approved Health (4% of products)

Target Groups

Adult (18 - 50 Years) Gluten Free

Product Information

📋 Directions for Use

2 caplets per day

Suggested use: Take two caplets daily, with food. For easier swallowing, take with water before and during ingestion. Caplets can be taken together or at different times during the day. Take 4-6 weeks to see results.

⚠️ Warnings & Precautions

Store in a cool, dry place, out of reach of children.

Do not use if imprinted seal under cap is broken or missing.

Caution: If you are pregnant or nursing, or allergic to shellfish, consult your health care professional before taking this product.

Caution: If you are pregnant or nursing, or allergic to shellfish, consult your health care professional before taking this product. Contains: Shellfish (shrimp & crab).

🧪 Formulation Notes

Glucosamine 1500 mg A natural compound found in connective tissue that is a building block for cartilage that helps maintain the structural integrity you need for healthy joints. Chondroitin 800 mg Chondroitin helps keep your joints moving smoothly by helping to support joint lubrication. MSM 750 mg A source of dietary sulfur, a mineral used by the body in collagen, connective tissue, and joint cartilage. Vitamin D3 2000 IU Vitamin D helps support healthy bones and muscles.

Glucosamine 1500 mg Chondroitin 800 mg MSM 750 mg Vitamin D3 2000 IU

Contains: Shellfish (shrimp & crab).

Color derived from natural source - no synthetic dyes No artificial flavors No preservatives No yeast Gluten free

Additional Information

Comfort Mobility Flexibility Triple-ingredient Triple-action Triple-benefit Cartilage Synovial fluid Bone Muscle Tendon Glucosamine 1500 mg: Helps support joint cartilage and helps to maintain joint comfort and flexibility. Chondroitin 800 mg: A naturally occurring nutrient found in connective tissue that helps support healthy joint cartilage. MSM 750 mg: A source of dietary sulfur, a mineral used by the body in collagen, connective tissue, and joint cartilage. Vitamin D3 2000 IU: Vitamin D3 helps support healthy bones and muscles.

Live an active life style with Nature Made TripleFlex with Vitamin D3 2000 IU. Vitamin D3 2000 IU combines with TripleFlex's other key nutrients to help support healthy joints and muscles.

Triple strength

Keep bottle tightly closed. Store in a cool, dry place, out of reach of children.

Tableted and quality tested in the U.S.A.

TripleFlex with Vitamin D3 caplets are made to Nature Made's guaranteed purity and potency standards.

Product Details

UPC / SKU 0 31604 01158 1
DSLD Entry Date 2018-07-25
Product Type Other Combinations
Form Other (e.g. tea bag)
Brand Nature Made
DSLD ID 179359
Data Updated 2026-04-11

Research Evidence

872 Research Sources
53 Avg Quality Score
309 Meta Analysis
309 Clinical Trial
111 Rct
71 Systematic Review
55 Guideline
4 Cochrane Review
4 Regulatory Source
2 Other
2 Narrative Review
2 Observational
1 Openfda Safety
A Vitamin D and vitamin D analogues for preventing fractures associated with involutional and post-menopausal osteoporosis
Meta Analysis The Cochrane database of systematic reviews 2009
A Vitamin D supplementation for prevention of mortality in adults
Meta Analysis The Cochrane database of systematic reviews 2014
A Vitamin D and vitamin D analogues for preventing fractures in post-menopausal women and older men
Meta Analysis The Cochrane database of systematic reviews 2014
A Vitamin D supplementation for prevention of cancer in adults
Meta Analysis The Cochrane database of systematic reviews 2014
A Interventions for preventing falls in older people in care facilities and hospitals
Meta Analysis The Cochrane database of systematic reviews 2018
A Drugs for preventing lung cancer in healthy people
Meta Analysis The Cochrane database of systematic reviews 2020
A Vitamin D supplementation for prevention of mortality in adults
Meta Analysis The Cochrane database of systematic reviews 2011
A High prevalence of vitamin D deficiency in Asia: A systematic review and meta-analysis
Meta Analysis Critical reviews in food science and nutrition 2023
A The effect of vitamin D supplementation on depressive symptoms in adults: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Critical reviews in food science and nutrition 2023
A Interventions for preventing falls in older people living in the community
Meta Analysis The Cochrane database of systematic reviews 2009
View all evidence for Vitamin D →

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