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TripleFlex With Vitamin D3

product on market Other (e.g. tea bag) Nature Made Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 60% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · methodology

Glucosamine, chondroitin, and MSM are commonly used to support joint health, though research shows moderate to limited evidence regarding their efficacy. Vitamin D3 supports bone density and immune function with strong clinical backing. This combination of ingredients is generally recognized as safe for most adults.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for TripleFlex With Vitamin D3
Open Full PDF View on NIH DSLD →
Details

Label Data

2 Caplet(s)
Serving Size
40
Servings
Other Combinations
Product Type
60%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

2000 IU (500% DV)
3.3× RDA — above typical dose (UL: 0.1 mg) 608 studies (A:16, B:251)
Sodium
75 mg (3% DV)
Market median: 1000.0mg (1115 products) 24 studies (A:0, B:9)
Market median: 600.0mg (79 products) 25 studies (A:0, B:6)
Market median: 1000.0mg (2 products)

Other Ingredients

Glucosamine Hydrochloride Sodium Chondroitin Sulfate Methylsulfonylmethane Hypromellose Color added Silicon Dioxide Magnesium Stearate Glyceryl Behenate Polyethylene Glycol Corn Starch Triethyl Citrate Polysorbate 80 Vitamin D3
Claims

Label Claims — Verification

Unverified Nutrient
Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

2 caplets per day

Suggested use: Take two caplets daily, with food. For easier swallowing, take with water before and during ingestion. Caplets can be taken together or at different times during the day. Take 4-6 weeks to see results.

Warnings & Precautions

Store in a cool, dry place, out of reach of children.

Do not use if imprinted seal under cap is broken or missing.

Caution: If you are pregnant or nursing, or allergic to shellfish, consult your health care professional before taking this product.

Caution: If you are pregnant or nursing, or allergic to shellfish, consult your health care professional before taking this product. Contains: Shellfish (shrimp & crab).

Formulation Notes

Glucosamine 1500 mg A natural compound found in connective tissue that is a building block for cartilage that helps maintain the structural integrity you need for healthy joints. Chondroitin 800 mg Chondroitin helps keep your joints moving smoothly by helping to support joint lubrication. MSM 750 mg A source of dietary sulfur, a mineral used by the body in collagen, connective tissue, and joint cartilage. Vitamin D3 2000 IU Vitamin D helps support healthy bones and muscles.

Glucosamine 1500 mg Chondroitin 800 mg MSM 750 mg Vitamin D3 2000 IU

Contains: Shellfish (shrimp & crab).

Color derived from natural source - No synthetic dyes No artificial flavors No preservatives No yeast Gluten free

Additional Information

Comfort Mobility Flexibility Triple-ingredient Triple-action Triple-benefit Cartilage Synovial fluid Bone Muscle Tendon Glucosamine 1500 mg: Helps support joint cartilage and helps to maintain joint comfort and flexibility. Chondroitin 800 mg: A naturally occurring compound found in connective tissue that helps support healthy cartilage. MSM 750 mg: A source of dietary sulfur, a mineral used by the body in collagen, connective tissue, and joint cartilage. Vitamin D3 2000 IU: Vitamin D3 helps support healthy bones and muscles.

List No. 1157 P201 Cat: A604 1A160

Live an active life style with Nature Made TripleFlex with vitamin D3 2000 IU. Vitamin D3 2000 IU combines with TripleFlex's other key nutrients to help support healthy joints and muscles.

Triple strength

Keep bottle tightly closed. Store in a cool, dry place, out of reach of children.

Tableted and quality tested in the U.S.A.

TripleFlex with Vitamin D3 caplets are made to Nature Made's guaranteed purity and potency standards.

Metadata

Product Details

UPC / SKU0 31604 01157 4
DSLD Entry Date2018-07-25
Product TypeOther Combinations
FormOther (e.g. tea bag)
DSLD ID179356
Data Updated2026-04-11
Research

Research Evidence

872
Research Sources
53
Avg Quality
309
Meta Analysis
309
Clinical Trial
111
Rct
71
Systematic Review
55
Guideline
4
Cochrane Review
4
Regulatory Source
2
Other
2
Narrative Review
2
Observational
1
Openfda Safety
A Vitamin D and vitamin D analogues for preventing fractures associated with involutional and post-menopausal osteoporosis
Meta Analysis The Cochrane database of systematic reviews 2009 PubMed DOI
A Vitamin D supplementation for prevention of mortality in adults
Meta Analysis The Cochrane database of systematic reviews 2014 PubMed DOI
A Vitamin D and vitamin D analogues for preventing fractures in post-menopausal women and older men
Meta Analysis The Cochrane database of systematic reviews 2014 PubMed DOI
A Vitamin D supplementation for prevention of cancer in adults
Meta Analysis The Cochrane database of systematic reviews 2014 PubMed DOI
A Interventions for preventing falls in older people in care facilities and hospitals
Meta Analysis The Cochrane database of systematic reviews 2018 PubMed DOI
A Drugs for preventing lung cancer in healthy people
Meta Analysis The Cochrane database of systematic reviews 2020 PubMed DOI
A Vitamin D supplementation for prevention of mortality in adults
Meta Analysis The Cochrane database of systematic reviews 2011 PubMed DOI
A High prevalence of vitamin D deficiency in Asia: A systematic review and meta-analysis
Meta Analysis Critical reviews in food science and nutrition 2023 PubMed DOI
A The effect of vitamin D supplementation on depressive symptoms in adults: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Critical reviews in food science and nutrition 2023 PubMed DOI
A Interventions for preventing falls in older people living in the community
Meta Analysis The Cochrane database of systematic reviews 2009 PubMed DOI
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.