TriFlex Soft Chews Salted Caramel by GNC — Ingredients, Evidence & Safety

Product Label

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Label Data

1 Chew(s) Serving Size

Non-Nutrient/Non-Botanical Product Type

33% Evidence Coverage

Supplement Facts — Evidence Check

Calories

20 Calorie(s)

Total Carbohydrates

4 Gram(s) (2% DV)

Sodium

40 mg (2% DV)

Glucosamine Hydrochloride

500 mg

📊 Market median: 1000.0mg (1115 products) 📚 22 studies (Tier A: 0, B: 9)

This product: 500mg

Chondroitin Sulfate Sodium

400 mg

📊 Market median: 600.0mg (79 products) 📚 24 studies (Tier A: 0, B: 6)

This product: 400mg

Methylsulfonylmethane

25 mg

📊 Market median: 1000.0mg (2 products)

This product: 25mg

Other Ingredients

Maltitol syrup Isomalt nonfat Milk powder Natural and Artificial flavors Xylitol Sunflower Oil Trehalose Soy Lecithin Glycerin Caramel Lactic Acid Sucralose

Label Claims — Verification

❓ All Other

❓ Structure/Function

All Other (100% of products) Structure/Function (89% of products) Nutrient (16% of products)

Target Groups

Adult (18 - 50 Years) Gluten Free Sugar Free

Product Information

📋 Directions for Use

Directions: As a dietary supplement for adults, take one soft chew three times a day, preferably with meals.

⚠️ Warnings & Precautions

Contains: Crustaceans (shrimp), milk and soybeans.

Keep out of reach of children.

🧪 Formulation Notes

Glucosamine and Chondroitin plus MSM

Gluten free and sugar free

Contains: Crustaceans (shrimp), milk and soybeans.

^Contributes a trivial amount of sugar

They has Glucosamine and Chondroitin to help support joint mobility and flexibility. They also contain MSM.

These delicious soft chews are gluten and sugar free.

Additional Information

Support joint mobility and flexibility

Natural and artificial flavors

CODE 534871 DSG

Gf Gluten free

Store in a cool, dry place.

Plus they're individually wrapped, making them easy to take on the go.

Our quality commitment to you Since 1935, our mission as the industry leader has been to provide you with the highest-quality nutritional supplements. We continue to stand behind this mission. If you're not 100% satisfied with your purchase, return the unused portion of the product with your receipt within 30 days, and we'll either refund your money or find a replacement product that is right for you.

Product Details

UPC / SKU 0 48107 17963 2

DSLD Entry Date 2018-03-23

Product Type Non-Nutrient/Non-Botanical

Form Other (e.g. tea bag)

Brand GNC

DSLD ID 174870

Data Updated 2026-04-11

Research Evidence

39 Research Sources

50 Avg Quality Score

20 Rct

9 Meta Analysis

4 Clinical Trial

3 Systematic Review

1 Regulatory Source

1 Openfda Safety

B Interventions for the management of temporomandibular joint osteoarthritis

Systematic Review The Cochrane database of systematic reviews 2012

PubMed DOI Cochrane

B Glucosamine therapy for treating osteoarthritis

Meta Analysis The Cochrane database of systematic reviews 2005

PubMed Cochrane

B Chondroitin for osteoarthritis

Meta Analysis The Cochrane database of systematic reviews 2015

PubMed DOI Cochrane

B Efficacy and safety of the combination of glucosamine and chondroitin for knee osteoarthritis: a systematic review and meta-analysis

Meta Analysis Archives of orthopaedic and trauma surgery 2023

PubMed DOI

B Glucosamine, chondroitin sulfate, and the two in combination for painful knee osteoarthritis

Rct The New England journal of medicine 2006

PubMed

B Oral Glucosamine in the Treatment of Temporomandibular Joint Osteoarthritis: A Systematic Review

Systematic Review International journal of molecular sciences 2023

PubMed DOI

B Scientific Opinion on glucosamine and joint health

Regulatory Source EFSA Journal 2009

DOI

B Clinical Efficacy and Safety of Chondroitin Combined with Glucosamine in the Treatment of Knee Osteoarthritis: A Systematic Review and Meta-Analysis

Meta Analysis Computational and mathematical methods in medicine 2022

PubMed DOI

B Combined chondroitin sulfate and glucosamine for painful knee osteoarthritis: a multicentre, randomised, double-blind, non-inferiority trial versus celecoxib

Rct Annals of the rheumatic diseases 2016

PubMed DOI

B Effectiveness and safety of glucosamine and chondroitin for the treatment of osteoarthritis: a meta-analysis of randomized controlled trials

Meta Analysis Journal of orthopaedic surgery and research 2018

PubMed DOI

View all evidence for Glucosamine →