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Homocysteine Shield

product on market Tablet or Pill Country Life Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 50% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · methodology

B6, B12, and folic acid are supported by strong evidence for reducing homocysteine levels. Trimethylglycine provides an additional pathway for methylation, while grape skin extract offers antioxidant properties. Overall, the evidence for these ingredients in managing homocysteine is well-established.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for Homocysteine Shield
Open Full PDF View on NIH DSLD →
Details

Label Data

2 Tablet(s)
Serving Size
30
Servings
Other Combinations
Product Type
50%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

25 mg (1250% DV)
19.2× RDA — above typical dose (UL: 100 mg) 114 studies (A:3, B:35)
800 mcg (200% DV)
2.0× RDA — within safe limits 226 studies (A:10, B:105)
1000 mcg (16667% DV)
416.7× RDA — above typical dose 139 studies (A:1, B:44)
Market median: 496.0mg (192 products) 20 studies — no high-quality reviews
Grape Skin Extract
50 mg
Red Wine Extract
50 mg

Other Ingredients

Cellulose Stearic Acid Cellulose & Glycerin Coating Silica Magnesium Stearate Vanilla Vegetable Glaze
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Directions: Adults take two (2) tablets daily with food or as directed by a health care professional. Do not exceed recommended dose. As a reminder, discuss the supplements and medications that you take with your health care providers.

Warnings & Precautions

Do not accept if seal is broken.

Keep out of the reach of children.

If any adverse reactions occur, stop taking the product and consult your doctor.

WARNING: If you are pregnant or nursing, taking medication or planning a surgery, consult your doctor before using this product.

Formulation Notes

NO: Yeast, wheat, gluten, milk, salt, preservatives or artificial color.

Gluten-Free

B VITAMINS

Additional Information

Certified Vegan AVA(TM) American Vegetarian Association Certified GF(R) Gluten-Free Good Manufacturing Practices GMP CERTIFIED PLEASE RECYCLE (recycle) Our manufacturing supports wind power renewablechoice.com

Product No. 1623 05J11L

Store between 59(0)-86(0) F.

This product has been manufactured at an NSF GMP Registered facility.

A B vitamin complex to help support healthy homocysteine levels already within normal range Supports cardiovascular health

Metadata

Product Details

UPC / SKU0 15794 01623 6
DSLD Entry Date2012-10-25
Product TypeOther Combinations
FormTablet or Pill
BrandCountry Life
DSLD ID14050
Data Updated2026-04-11
Research

Research Evidence

153
Research Sources
55
Avg Quality
71
Systematic Review
51
Meta Analysis
19
Rct
6
Clinical Trial
2
Other
2
Regulatory Source
1
Openfda Safety
A Efficacy of vitamin and antioxidant supplements in prevention of cardiovascular disease: systematic review and meta-analysis of randomised controlled trials
Meta Analysis BMJ (Clinical research ed.) 2013 PubMed DOI
A Homocysteine lowering interventions for preventing cardiovascular events
Meta Analysis The Cochrane database of systematic reviews 2009 PubMed DOI
A Intake of vitamin B6, folate, and vitamin B12 and risk of coronary heart disease: a systematic review and dose-response meta-analysis of prospective cohort studies
Meta Analysis Critical reviews in food science and nutrition 2019 PubMed DOI
A Exploring the causal associations of micronutrients on urate levels and the risk of gout: A Mendelian randomization study
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2024 PubMed DOI
A Pyridoxine (vitamin B6) supplementation during pregnancy or labour for maternal and neonatal outcomes
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
B Prophylactic drug management for febrile seizures in children
Meta Analysis The Cochrane database of systematic reviews 2021 PubMed DOI
B Treatments for Hyperemesis Gravidarum and Nausea and Vomiting in Pregnancy: A Systematic Review
Systematic Review JAMA 2016 PubMed DOI
B The potential role of nutritional components in improving brain function among patients with Alzheimers disease: a meta-analysis of RCT studies
Meta Analysis Neurosciences (Riyadh, Saudi Arabia) 2020 PubMed DOI
B Pyridoxine (vitamin B6) supplementation in pregnancy
Meta Analysis The Cochrane database of systematic reviews 2006 PubMed
B Effect of ginger in the treatment of nausea and vomiting compared with vitamin B6 and placebo during pregnancy: a meta-analysis
Meta Analysis The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians 2022 PubMed DOI
View all evidence for Vitamin B6 →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.