Poly C

product on market Tablet or Pill USANA Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 50% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · methodology

Vitamin C, quercetin, and rutin are supported by moderate evidence for their roles as antioxidants and immune system supports. Citrus bioflavonoids further assist in enhancing the bioavailability and activity of these compounds. Research indicates these ingredients generally contribute to cellular protection and vascular health.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for Poly C
Open Full PDF View on NIH DSLD →
Details

Label Data

2 Tablet(s)
Serving Size
Botanical with Nutrients
Product Type
50%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Vitamin C
1200 mg (2000% DV)
Market median: 500.0mg (283 products) 174 studies (A:0, B:62)
14 mg
Market median: 500.0mg (19 products)
6 mg
Market median: 500.0mg (283 products) 174 studies (A:0, B:62)

Other Ingredients

Microcrystalline Cellulose pregelatinized Starch Ascorbyl Palmitate Hydroxypropyl Methylcellulose Silicon Dioxide, Colloidal
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

DIRECTIONS: TAKE TWO (2) TABLETS DAILY, OR AS YOUR PERSONAL NEEDS REQUIRE.

Additional Information

USANA DIFFERENCE -Effective-Safe-Science-based-Pharmaceutical Quality In 1928, Albert Szent-Gyorgyi isolated a chemical that protected fruits against discoloration and infection when bruised. In 1937 he won a Nobel Prize for his discovery-the chemical substance we now know as vitamin C. Vitamin C plays many important roles in the body, and because human bodies are incapable of manufacturing vitamin C, we must rely on our diet to satisfy our daily requirement. The amount of vitamin C needed daily for optimal performance is directly related to individual ingestion, absorption, utilization, metabolism, excretion, work environment, and physical, mental, and environmental stress. Everyone has a different biochemistry and unique lifestyle. While vitamin C deficiency is rare today, we may still not receive sufficient amounts for our individual health needs.1,2 Poly C(R) supplement provides optimal vitamin C protection with a unique bland of mineral ascorbates that provides higher levels of vitamin C in the blood than from equal amounts of ascorbic acid. THE MANY ROLES OF VITAMIN C Critical to good health, vitamin C supports many important functions in the body. First, it is essential for collagen synthesis. collagen is the most abundant structural protein in the body and is essential for staying healthy and strengthening muscles, teeth, bones, skin, and blood vessels. Without adequate vitamin C, there is inadequate collagen.3,5,7 Under normal conditions, the RDA of 75-90 mg per day meets the requirement for maintaining collagen. But we also need vitamin C to quench free radicals, prevent lipid oxidation, and regenerate other antioxidants.4 It is a co-factor or co-substrate for many enzyme systems involved in such functions as ATP synthesis within mitochondria and hormone biosynthesis.5 Vitamin C can help retain cardiovascular health by supporting healthy adrenal function and healthy arterial wall integrity.6 And, vitamin C helps support a healthy immune system, which is responsible for defending your body against millions of bacteria, microbes, viruses, toxins, and parasites every day.7 You also need enough vitamin C to protect the liver from environmental toxins and drug metabolites and to make carnitine, interferon, and prostaglandin E1.7 Thus, a daily does of 75-90 mg is unlikely to be sufficient for everyone.8 One tablet of Poly C provides 600 mg of vitamin C protection.

Health Basics -Vitamin C carries dual importance as the body's premier water-soluble antioxidant and as a coenzyme essential for the synthesis of connective tissues in the skin and throughout the body -Promotes healthy cardiovascular function, vision, immune function -Complements the USANA Essentials(TM), providing extra vitamin C during times of everday stress Did You Know? -Poly C(R)'s unique blend of mineral ascorbates provides superior bioavailability and prolonged vitamin C activity while reducing the risk of stomach irritation -A synergistic blend of bioflavonoids is added to Poly C for additional antioxidant protection

LABORATORY TESTED, QUALITY GUARANTEED. MEETS USP SPECIFICATIONS FOR POTENCY, UNIFORMITY, AND DISINTEGRATION, WHERE APPLICABLE.

References 1. Gale CR, el al. BMJ 1995;31(6994):1563-G. 2. Enstrom JE, et al, Epidemiology 1992;3(3):194-202. 3. Murad S, et al. Proc Natl Acd Sci 1981;78(5):2879-82. 4. Harats D, et al. Atherosclerosis 1990;85(1):47-54. 5. Padh H. Nutri Rev 1991;49(3):65-70. 6. Patak P, et al. Endocr Res 2004;30(4):871-5. 7. Englard S, Seifter S, Annu Rev Nutr 1986;6:365-406. 8. Carr AC, Frei B. Am J Clin Nutr 1999;69:1086-107.

Optimizers/Cellular Metabolic Item# 130 (Chart) VITAMIN C LEVELS IN THE BLOOD aPlasma vitamin C (pM) 60 80 100 120 140 Time (hours) 0 2 4 6 8 10 Taking USANA's Poly C yields higher levels of vitamin C in the blood than ascorbic acid (AsA=vitamin C), and keeps the levels higher for a longer period of time.

Metadata

Product Details

DSLD Entry Date2012-10-01
Product TypeBotanical with Nutrients
FormTablet or Pill
BrandUSANA
DSLD ID12946
Data Updated2026-04-11
Research

Research Evidence

371
Research Sources
54
Avg Quality
148
Meta Analysis
82
Systematic Review
71
Rct
62
Clinical Trial
2
Regulatory Source
1
Cochrane Review
1
Narrative Review
1
Other
1
Openfda Safety
A Vitamin C supplementation in pregnancy
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
A Vitamin C supplementation for the primary prevention of cardiovascular disease
Systematic Review The Cochrane database of systematic reviews 2017 PubMed DOI
A Vitamin C for preventing and treating the common cold
Meta Analysis The Cochrane database of systematic reviews 2013 PubMed DOI
A Vitamin C for preventing and treating pneumonia
Meta Analysis The Cochrane database of systematic reviews 2013 PubMed DOI
A Vitamin E supplementation in pregnancy
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
A Vitamin C supplementation for prevention and treatment of pneumonia
Meta Analysis The Cochrane database of systematic reviews 2020 PubMed DOI
A Vitamin C supplementation for prevention and treatment of pneumonia
Systematic Review The Cochrane database of systematic reviews 2021 PubMed DOI
A Nutritional interventions for preventing and treating pressure ulcers
Meta Analysis The Cochrane database of systematic reviews 2024 PubMed DOI
A Does Vitamin C Supplementation Provide a Protective Effect in Periodontal Health? A Systematic Review and Meta-Analysis
Meta Analysis International journal of molecular sciences 2024 PubMed DOI
A Circulating vitamin C concentration and risk of cancers: a Mendelian randomization study
Meta Analysis BMC medicine 2021 PubMed DOI
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.