🟢 100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 75% of ingredients have research evidence
A Label Compliance Grade

Product Label

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Label Data

1 Capsule(s) Serving Size
120 Servings
Other Combinations Product Type
75% Evidence Coverage

Supplement Facts — Evidence Check

30 mg (2000% DV)
📊 25.0× RDA — above typical dose 📚 76 studies (Tier A: 0, B: 33)
RDA 1.2mg This product: 30mg
20 mg (100% DV)
✅ 1.4× RDA — within safe limits 📚 193 studies (Tier A: 5, B: 63)
RDA 14mg This product: 20mg UL 35mg
500 mcg (8333% DV)
📊 208.3× RDA — above typical dose 📚 138 studies (Tier A: 1, B: 44)
RDA 0.0024mg This product: 0.5mg
CONCENTRATED WEIGHT LOSS AND ENERGY MATRIX(TM) Proprietary Blend
395 mg

Other Ingredients

Gelatin Microcrystalline Cellulose Magnesium Stearate FD&C Blue No. 1 Titanium Dioxide

Label Claims — Verification

All Other
Structure/Function
All Other (99% of products) Structure/Function (83% of products) Nutrient (47% of products)

Target Groups

Adult (18 - 50 Years)

Product Information

📋 Directions for Use

Suggested Use: Take one (1) capsule in the morning and one (1) capsule in the afternoon, on an empty stomach, or as directed by a qualified healthcare practitioner.

⚠️ Warnings & Precautions

Not intended for use by those with a medical condition. Get the consent of a licensed physician before using this product, especially if you are taking medication, have a medical condition, or thinking about becoming pregnant. Discontinue two weeks prior to surgery.

Caution: Methoxyburn contains the B vitamin niacin. Niacin may cause temporary flushing, tingling, skin reddening, and sensations of heat, especially if taken on an empty stomach. This is a natural and harmless reaction.

KEEP THIS PRODUCT AND ALL SUPPLEMENTS OUT OF THE REACH OF CHILDREN.

DO NOT USE IF SAFETY SEAL IS BROKEN.

Warnings: Not intended for use by persons under age 18.

Do not exceed recommended dose. Do not take for more than eight (8) consecutive weeks.

This product should not be taken by pregnant or lactating women.

Caffeine Warning: The recommended serving of this product contains approximately as much caffeine as two cups of coffee. Do not consume caffeine, or combine with synephrine from other sources, including but not limited to coffee, tea, soda and other dietary supplements or medications containing phenylephrine or caffeine. Too much caffeine may cause nervousness, irritability, sleeplessness, and occasionally rapid heartbeat. Discontinue use if you experience dizziness, severe headache, rapid heartbeat or shortness of breath.

Additional Information

LOSE WEIGHT The metabolic rate enhancers in MethoxyBurn(TM) are paired with high-grade phytochemical extracts designed to act along the principle pathways influencing weight management-including cyclic-AMP modulation, CNS modulation and thyroid modulation.

APPETITE CONTROL For maximum effectiveness and metabolic benefit, the metabolic rate enhancers and complementary constituent compounds are designed to act along the pathways principally responsible for controlling appetite and caloric intake.

WEIGHT LOSS APPETITE CONTROL

LOSE WEIGHT FEEL ENERGIZED APPETITE CONTROL

Please read entire label before use.

(chart) SHOWN TO REDUCE FAT BY UP TO 41.3% REDUCTION IN FAT WEIGHT (Express In Milligrams) Visceral Fat Visceral Fat High-Fat Diet Model Ilex paraguarinsis Ext. Model As a component constituent, compared to a high-fat fed diet control, as shown in independent 3rd party research model.

FOR MAXIMUM RESULTS COMBINE WITH: GRP6(TM) 1 CAPSULE 1 HOUR PRIOR TO BEDTIME GUAVA(TM) SUPER FRUIT 1 CAPSULE IN THE MORNING 1 CAPSULE IN THE AFTERNOON

Dr. Gary I. Weinberger is a member of Pro Nutra's scientific advisory board.

Promotes Weight Loss, Appetite Control, Enhanced Mood and Energy.

When combined with a proper exercise and nutrition regimen. Statements based on early-stage independent 3rd party in vivo and / or in vitro model scientific research data findings.

FEEL ENERGIZED

"MethoxyBurn is an effective weight loss formula for energy enhancement and increased metabolic rate and function. MethoxyBurn is most definitely in a class by itself." -Gary I. Weinberger, MD

PHYSICIAN RECOMMENDED

SHOWN TO INCREASE ENERGY BY UP TO 250% EPINEPHRINE (ADRENALINE) LEVELS [pg/mL 120min] METHYLXANTHINE CONTROL GROUP As a component constituent, compared to control group, as shown in independent 3rd party research model.

EXCLUSIVE LARGER SIZE - 2 MONTH SUPPLY

The Ultimate Feel Good Weight Loss Formula

Rev. 01-001-MET003 04/12

Product Details

UPC / SKU 8 51330 00406 6
DSLD Entry Date 2013-04-25
Product Type Other Combinations
Form Capsule
Brand Pro-Nutra
DSLD ID 12411
Data Updated 2026-04-11

Research Evidence

100 Research Sources
56 Avg Quality Score
48 Systematic Review
30 Meta Analysis
13 Rct
6 Clinical Trial
1 Cochrane Review
1 Regulatory Source
B Thiamine for prevention and treatment of Wernicke-Korsakoff Syndrome in people who abuse alcohol
Systematic Review The Cochrane database of systematic reviews 2013
B Efficacy of B-vitamins and vitamin D therapy in improving depressive and anxiety disorders: a systematic review of randomized controlled trials
Systematic Review Nutritional neuroscience 2023
B Effect of thiamine supplementation on glycaemic outcomes in adults with type 2 diabetes: a systematic review and meta-analysis
Meta Analysis BMJ open 2022
B Effect of intravenous thiamine administration on critically ill patients: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2024
B Effect of adjunctive vitamin C, glucocorticoids, and vitamin B1 on longer-term mortality in adults with sepsis or septic shock: a systematic review and a component network meta-analysis
Systematic Review Intensive care medicine 2022
B Effect of Combined Diclofenac and B Vitamins (Thiamine, Pyridoxine, and Cyanocobalamin) for Low Back Pain Management: Systematic Review and Meta-analysis
Meta Analysis Pain medicine (Malden, Mass.) 2020
B Thiamine, Ascorbic Acid, and Hydrocortisone As a Metabolic Resuscitation Cocktail in Sepsis: A Meta-Analysis of Randomized Controlled Trials With Trial Sequential Analysis
Meta Analysis Critical care medicine 2021
B The effects of thiamine supplementation on patients with heart failure: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Complementary therapies in medicine 2022
B Hydrocortisone Combined with Vitamin C and Thiamine in the Treatment of Sepsis/Septic Shock: A Systematic Review with Meta-Analysis and Trial Sequential Analysis
Meta Analysis Clinical and investigative medicine. Medecine clinique et experimentale 2023
B Thiamine for Wernicke-Korsakoff Syndrome in people at risk from alcohol abuse
Systematic Review The Cochrane database of systematic reviews 2004
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