🟢 100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 14% of ingredients have research evidence
B Label Compliance Grade

Product Label

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Label Data

3 Tablet(s) Serving Size
Botanical Product Type
14% Evidence Coverage

Supplement Facts — Evidence Check

75 mg
📊 Market median: 250.0mg (562 products) 📚 53 studies (Tier A: 0, B: 19)
This product: 75mg
125 mg
📊 Market median: 300.0mg (159 products)
Median 300.0mg This product: 125mg
Boldo Leaf
125 mg
📊 Market median: 60.0mg (107 products) 📚 1 studies — no high-quality reviews
This product: 100mg
Quassia Bark
100 mg
Red Clover Tops
100 mg
White Oak Bark
50 mg

Other Ingredients

Di-Calcium Phosphate Cellulose Gelatin Stearic Acid Magnesium Stearate

Label Claims — Verification

All Other
All Other (99% of products) Structure/Function (83% of products) Nutrient (4% of products)

Target Groups

Adult (18 - 50 Years)

Product Information

📋 Directions for Use

SUGGESTED USE: As a dietary supplement, take three tablets daily with meals.

⚠️ Warnings & Precautions

KEEP OUT OF REACH OF CHILDREN

Additional Information

Keep tightly capped in a cool, dry place.

Product Details

DSLD Entry Date 2012-08-24
Product Type Botanical
Form Tablet or Pill
DSLD ID 12151
Data Updated 2026-04-11

Research Evidence

69 Research Sources
55 Avg Quality Score
34 Meta Analysis
26 Systematic Review
5 Rct
3 Clinical Trial
1 Openfda Safety
A Silymarin for adults with metabolic dysfunction-associated steatotic liver disease
Meta Analysis The Cochrane database of systematic reviews 2025
B Evaluation of the effect of herbal agents as management of radiodermatitis in breast cancer patients: A systematic review and meta-analysis
Meta Analysis Japan journal of nursing science : JJNS 2024
B Efficacy of different interventions for nonalcoholic fatty liver disease: A meta-analysis of lifestyle modifications, silymarin, and medications
Meta Analysis Asia Pacific journal of clinical nutrition 2025
B Milk thistle for alcoholic and/or hepatitis B or C virus liver diseases
Meta Analysis The Cochrane database of systematic reviews 2007
B Pharmacotherapy for trichotillomania
Meta Analysis The Cochrane database of systematic reviews 2021
B Effects berberine-silymarin on liver enzymes: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Clinical nutrition ESPEN 2022
B Efficacy of traditional Chinese medicine combined with Silibinin on nonalcoholic fatty liver disease: A meta-analysis and systematic review
Meta Analysis Medicine 2024
B Are alterations needed in Silybum marianum (Silymarin) administration practices? A novel outlook and meta-analysis on randomized trials targeting liver injury
Meta Analysis BMC complementary medicine and therapies 2025
B The therapeutic effects of silymarin for patients with glucose/lipid metabolic dysfunction: A meta-analysis
Meta Analysis Medicine 2020
B Administration of silymarin in NAFLD/NASH: A systematic review and meta-analysis
Meta Analysis Annals of hepatology 2024
View all evidence for Milk Thistle →

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