🟢 100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 44% of ingredients have research evidence
A Label Compliance Grade

Product Label

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Label Data

2 fl. Oz. Serving Size
Other Combinations Product Type
44% Evidence Coverage

Supplement Facts — Evidence Check

Calories
4 {Calories}
Calories from Fat
30 mg (150% DV)
✅ 2.1× RDA — within safe limits 📚 193 studies (Tier A: 5, B: 63)
RDA 14mg This product: 30mg UL 35mg
40 mg (2000% DV)
📊 30.8× RDA — above typical dose (UL: 100 mg) 📚 113 studies (Tier A: 3, B: 35)
RDA 1.3mg This product: 40mg UL 100mg
400 mcg (100% DV)
✅ Within RDA (1.0× RDA of 0.4 mg) 📚 225 studies (Tier A: 10, B: 105)
RDA 0.4mg This product: 0.4mg UL 1.0mg
500 mcg (833% DV)
📊 208.3× RDA — above typical dose 📚 138 studies (Tier A: 1, B: 44)
RDA 0.0024mg This product: 0.5mg
Sodium
10 mg (1% DV)
Energy Blend
1870 mg
Enzyme Blend
1 mg

Other Ingredients

purified Water Natural and Artificial flavors Potassium Sorbate Sodium Benzoate and EDTA Sucralose

Label Claims — Verification

All Other
Structure/Function
All Other (98% of products) Structure/Function (89% of products) Nutrient (43% of products)

Target Groups

Children 4 or More Years of Age Adult (18 - 50 Years)

Product Information

📋 Directions for Use

FOR MAXIMUM ENERGY: Drink entire bottle at one time.

FOR MODERATE ENERGY: Drink a half bottle or less. Use or discard within 72 hours (or 3 days) after opening. Refrigeration not necessary.

⚠️ Warnings & Precautions

CAUTION: Contains about as much caffeine as a cup of coffee. Limit caffeine products to avoid nervousness, sleeplessness, and occasionally rapid heartbeat. You may experience a Niacin Flush (hot feeling, skin redness) that lasts a few minutes. This is caused by Niacin (Vitamin B3) increasing blood flow near the skin.

Phenylketonurics: Contains phenylalanine.

Not for use by children under 12 years of age.

🧪 Formulation Notes

amino Acids

b-vitamins

enzymes

Additional Information

*Individual results may vary.

All right reserved.

Individual results may vary.

MADE IN USA

PATENT PENDING

WHEN TO TAKE 5-HOUR ENERGY Take 5-Hour Energy whenever you need a big boost of energy… - Morning – Wake up, be alert & productive. - Afternoon – No more food coma. - Working out – More reps, more miles. - Going out – More energy – more fun. - Long trips – Avoid travel fatigue.

Product Details

DSLD Entry Date 2011-10-26
Product Type Other Combinations
Form Liquid
DSLD ID 1176
Data Updated 2026-04-11

Research Evidence

153 Research Sources
55 Avg Quality Score
71 Systematic Review
51 Meta Analysis
19 Rct
6 Clinical Trial
2 Other
2 Regulatory Source
1 Openfda Safety
A Efficacy of vitamin and antioxidant supplements in prevention of cardiovascular disease: systematic review and meta-analysis of randomised controlled trials
Meta Analysis BMJ (Clinical research ed.) 2013
A Homocysteine lowering interventions for preventing cardiovascular events
Meta Analysis The Cochrane database of systematic reviews 2009
A Intake of vitamin B6, folate, and vitamin B12 and risk of coronary heart disease: a systematic review and dose-response meta-analysis of prospective cohort studies
Meta Analysis Critical reviews in food science and nutrition 2019
A Exploring the causal associations of micronutrients on urate levels and the risk of gout: A Mendelian randomization study
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2024
A Pyridoxine (vitamin B6) supplementation during pregnancy or labour for maternal and neonatal outcomes
Meta Analysis The Cochrane database of systematic reviews 2015
B Prophylactic drug management for febrile seizures in children
Meta Analysis The Cochrane database of systematic reviews 2021
B Treatments for Hyperemesis Gravidarum and Nausea and Vomiting in Pregnancy: A Systematic Review
Systematic Review JAMA 2016
B The potential role of nutritional components in improving brain function among patients with Alzheimers disease: a meta-analysis of RCT studies
Meta Analysis Neurosciences (Riyadh, Saudi Arabia) 2020
B Pyridoxine (vitamin B6) supplementation in pregnancy
Meta Analysis The Cochrane database of systematic reviews 2006
B Effect of ginger in the treatment of nausea and vomiting compared with vitamin B6 and placebo during pregnancy: a meta-analysis
Meta Analysis The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians 2022
View all evidence for Vitamin B6 →

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