Home/ Supplements/ Vitamin K/ Osteo-Guard One-To-One

Osteo-Guard One-To-One

product on market Tablet or Pill Douglas Laboratories Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 60% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · methodology

This formula combines calcium, magnesium, phosphorus, and vitamin K1, which have strong evidence for supporting bone mineralization and density. Boron is included to further assist in mineral absorption, though evidence for its efficacy is more limited. The profile is generally considered safe for consumption.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for Osteo-Guard One-To-One
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Tablet(s)
Serving Size
120
Servings
Other Combinations
Product Type
60%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

7.5 mcg (9% DV)
Within RDA (0.1× RDA) 275 studies (A:9, B:175)
Calcium
125 mg (13% DV)
60 mg (6% DV)
Within RDA (0.1× RDA) 13 studies (A:0, B:3)
125 mg (31% DV)
Within RDA (0.3× RDA) 316 studies (A:8, B:159)
0.25 mg
Market median: 3.0mg (58 products) 3 studies — no high-quality reviews

Other Ingredients

Cellulose modified Cellulose Gum Vegetable Stearine Magnesium Stearate Silica
Claims

Label Claims — Verification

Unverified Nutrient
Unverified All Other
Info

Product Information

Directions for Use

Suggested Usage: As a dietary supplement, adults take 1 to 8 tablets daily or as directed by your healthcare professional.

Warnings & Precautions

WARNING: This product contains Vitamin K, which interferes with the prescription drugs Coumadin(R) and Warfarin. If you are taking these or similar prescription drugs, consult your healthcare professional before using this product.

Tamper resistant package, do not use if outer seal is missing.

KEEP OUT OF REACH OF CHILDREN.

Formulation Notes

Osteo-Guard(R) One-To-One, prepared from young bovine bone, provides calcium and phosphorus (as microcrystalline hydroxyapatite), trace minerals, bone matrix proteins, amino acids and glycosaminoglycans in their natural forms and physiologic ratios found in whole bone. Magnesium is included in an equal amount to calcium, providing a calcium to magnesium ratio of one-to-one (1:1).

Additional Information

For optimal storage conditions, store in a cool, dry place. (59(0) - 77(0)F/15(0) - 25(0)C) (35-65% relative humidity)

OSG1

Metadata

Product Details

UPC / SKU7 45287 04012 6
DSLD Entry Date2012-10-01
Product TypeOther Combinations
FormTablet or Pill
BrandDouglas Laboratories
DSLD ID10984
Data Updated2026-04-11
Research

Research Evidence

332
Research Sources
59
Avg Quality
220
Meta Analysis
56
Systematic Review
30
Rct
16
Clinical Trial
3
Guideline
3
Regulatory Source
1
Narrative Review
1
Other
1
Openfda Safety
A Duration of treatment with vitamin K antagonists in symptomatic venous thromboembolism
Meta Analysis The Cochrane database of systematic reviews 2014 PubMed DOI
A Antiplatelet and anticoagulant agents for secondary prevention of stroke and other thromboembolic events in people with antiphospholipid syndrome
Meta Analysis The Cochrane database of systematic reviews 2017 PubMed DOI
A Anticoagulants (extended duration) for prevention of venous thromboembolism following total hip or knee replacement or hip fracture repair
Meta Analysis The Cochrane database of systematic reviews 2016 PubMed DOI
A Antiplatelet and anticoagulant agents for secondary prevention of stroke and other thromboembolic events in people with antiphospholipid syndrome
Meta Analysis The Cochrane database of systematic reviews 2020 PubMed DOI
A Direct factor Xa inhibitors versus low molecular weight heparins or vitamin K antagonists for prevention of venous thromboembolism in elective primary hip or knee replacement or hip fracture repair
Meta Analysis The Cochrane database of systematic reviews 2025 PubMed DOI
A Factor Xa inhibitors versus vitamin K antagonists for preventing cerebral or systemic embolism in patients with atrial fibrillation
Meta Analysis The Cochrane database of systematic reviews 2018 PubMed DOI
A Antiplatelet agents and anticoagulants for hypertension
Systematic Review The Cochrane database of systematic reviews 2022 PubMed DOI
A Primary prophylaxis for venous thromboembolism in ambulatory cancer patients receiving chemotherapy
Meta Analysis The Cochrane database of systematic reviews 2012 PubMed DOI
A Factor Xa inhibitors versus vitamin K antagonists for preventing cerebral or systemic embolism in patients with atrial fibrillation
Meta Analysis The Cochrane database of systematic reviews 2013 PubMed DOI
A Anticoagulation for the long-term treatment of venous thromboembolism in patients with cancer
Meta Analysis The Cochrane database of systematic reviews 2014 PubMed DOI
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.