🟢 100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 17% of ingredients have research evidence
B Label Compliance Grade

Product Label

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Label Data

2 Caplet(s) Serving Size
37 Servings
Other Combinations Product Type
17% Evidence Coverage

Supplement Facts — Evidence Check

Vitamin C
60 mg (100% DV)
2 mg (100% DV)
✅ Within RDA (0.9× RDA of 2.3 mg) 📚 8 studies — no high-quality reviews
RDA 2.3mg This product: 2mg UL 11mg
Sodium
40 mg (2% DV)
1500 mg
📊 Market median: 1000.0mg (1115 products) 📚 22 studies (Tier A: 0, B: 9)
This product: 1500mg
Joint Shield(TM) Proprietary Blend
1350 mg
3 mg
📊 Market median: 3.0mg (58 products) 📚 2 studies — no high-quality reviews
This product: 3mg UL 20mg

Other Ingredients

Crospovidone Cellulose Coating Titanium Dioxide color Cellulose Silica Vegetable Magnesium Stearate

Label Claims — Verification

All Other
Structure/Function
All Other (99% of products) Structure/Function (83% of products) Nutrient (54% of products)

Target Groups

Adult (18 - 50 Years)

Product Information

📋 Directions for Use

DIRECTIONS FOR ADULT USE: TAKE TWO (2) CAPLETS PER DAY WITH FOOD. As a reminder, discuss the supplements and medications you take with your health care providers. Note: You have the option of taking two caplets together or spread throughout the day.

⚠️ Warnings & Precautions

Not intended for use by persons under the age of 18.

CAUTION: If you are pregnant, nursing or taking any medications, consult your doctor before use.

Discontinue use and consult your doctor if any adverse reactions occur.

KEEP OUT OF REACH OF CHILDREN.

TAMPER RESISTANT: DO NOT USE IF SEAL UNDER CAP IS BROKEN OR MISSING.

🧪 Formulation Notes

Contains shellfish (shrimp, crab, lobster, crayfish) ingredients.

Additional Information

Helps to: Promote Mobility* Renew Cartilage* Maintain Healthy Connective Tissue* Based on the results of the National Disease and Therapeutic Index syndicated report among physicians who recommend a branded Glucosamine/Chondroitin or Glucosamine supplement, December 2009, and the results of the Pharmacy Times Survey among pharmacists who recommend a “bone/joint strengthener” dietary supplement, 2010. 1. This statement is based on two human studies of 5-LOXIN Advanced™ using subjective measures in which participants rate their joint health. In these studies, after 7 days, improvement continued to be seen, including in biomarker analysis.

ADVANCED SHOWS IMPROVEMENT IN Joint Comfort within 7 Days!1

STORE IN A DRY PLACE AND AVOID EXCESSIVE HEAT.

40 points

15471 08E B31357 MAZ

THE NATURAL AGING PROCESS CAN ADD EXCESSIVE STRESS ON YOUR JOINTS. ANNOYING FLARE-UPS CAN STRIKE AT ANY TIME. NOW THERE’S A DIFFERENT CHOICE TO SUPPORT HEALTHY JOINTS.

#1 DOCTOR & PHARMACIST RECOMMENDED BRAND

PROUD SPONSOR of the

ARTHRITIS FOUNDATION(R)

For information about arthritis, contact the Foundation at 1-800-568-4045 or www.arthritis.org

Part No. 22-15747

Product Details

UPC / SKU 0 30768 15471 4
DSLD Entry Date 2012-06-25
Product Type Other Combinations
Form Other (e.g. tea bag)
DSLD ID 10335
Data Updated 2026-04-11

Research Evidence

371 Research Sources
54 Avg Quality Score
148 Meta Analysis
82 Systematic Review
71 Rct
62 Clinical Trial
2 Regulatory Source
1 Cochrane Review
1 Narrative Review
1 Other
1 Openfda Safety
A Vitamin C supplementation in pregnancy
Meta Analysis The Cochrane database of systematic reviews 2015
A Vitamin C supplementation for the primary prevention of cardiovascular disease
Systematic Review The Cochrane database of systematic reviews 2017
A Vitamin C for preventing and treating the common cold
Meta Analysis The Cochrane database of systematic reviews 2013
A Vitamin C for preventing and treating pneumonia
Meta Analysis The Cochrane database of systematic reviews 2013
A Vitamin E supplementation in pregnancy
Meta Analysis The Cochrane database of systematic reviews 2015
A Vitamin C supplementation for prevention and treatment of pneumonia
Meta Analysis The Cochrane database of systematic reviews 2020
A Vitamin C supplementation for prevention and treatment of pneumonia
Systematic Review The Cochrane database of systematic reviews 2021
A Nutritional interventions for preventing and treating pressure ulcers
Meta Analysis The Cochrane database of systematic reviews 2024
A Does Vitamin C Supplementation Provide a Protective Effect in Periodontal Health? A Systematic Review and Meta-Analysis
Meta Analysis International journal of molecular sciences 2024
A Circulating vitamin C concentration and risk of cancers: a Mendelian randomization study
Meta Analysis BMC medicine 2021
View all evidence for Vitamin C →

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