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Transferrin Saturation
Percentage of transferrin bound to iron
Also known as: TSAT,Iron Saturation
Reference Ranges
Clinical Reference
20.0 – 50.0 %
Optimal Range
25.0 – 45.0 %
Critical Range
> 80.0
%
Calculated: Iron/TIBC x 100
Related Conditions
Hemochromatosis
High
Iron Deficiency Anemia
Low
Food & Lifestyle Recommendations
🍎 Food
Include heme iron (red meat, poultry) with vitamin C-rich foods; avoid tea/coffee with iron meals
Maximizes iron absorption
🍎 Food
If hemochromatosis suspected, limit iron-fortified foods and alcohol; avoid vitamin C with iron meals
Reduces further iron loading
Evidence-Backed Supplements
When Low
-
Iron supplementation raises saturation in iron deficiency
Ferrous bisglycinate 18–65 mg elemental/day Empty stomach -
Vitamin C increases non-heme iron absorption 2-3x
Vitamin C 250–500 mg with iron With iron
Questions to Ask Your Doctor
- Is this iron deficiency? Should we also check ferritin and a CBC? Full iron panel
- Could this indicate hemochromatosis? Should we do HFE genetic testing? Screens for iron overload disease
Upload your blood test to see how your Transferrin Saturation compares to reference and optimal ranges.
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