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SHBG
Regulates bioavailability of sex hormones
Also known as: Sex Hormone Binding Globulin
Reference Ranges
Clinical Reference
10.0 – 80.0 nmol/L
Optimal Range
20.0 – 60.0 nmol/L
Binds testosterone & estradiol
Related Conditions
Hyperthyroidism
High
Pcos
Low
Insulin Resistance
Low
Food & Lifestyle Recommendations
🍎 Food
Reduce refined carbs and added sugars; improve insulin sensitivity
Low SHBG is insulin-driven
🏃 Exercise
Regular aerobic exercise raises SHBG
Exercise improves insulin sensitivity
🏃 Exercise
Resistance training may lower SHBG; avoid excessive endurance
SHBG responds to training style
Evidence-Backed Supplements
When Low
-
Vitamin D sufficiency correlates with higher SHBG
Vitamin D3 2000–4000 IU/day With meal -
Omega-3 may raise SHBG modestly
EPA+DHA 2 g/day With meal
Questions to Ask Your Doctor
- Does this suggest insulin resistance? Should we check fasting insulin and HOMA-IR? Low SHBG strongly correlates with IR
Upload your blood test to see how your SHBG compares to reference and optimal ranges.
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