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IGF-1

Hormone Unit: ng/mL

Mediates growth hormone effects

Also known as: Insulin-like Growth Factor 1

Reference Ranges

Clinical Reference 80.0 – 280.0 ng/mL
Optimal Range 120.0 – 220.0 ng/mL

Age-dependent; declines after 30

Related Conditions

Acromegaly High
Growth Hormone Deficiency Low
Sarcopenia Low

Food & Lifestyle Recommendations

🍎 Food Ensure 1.2-2.0 g/kg/day protein; adequate calories — undernutrition lowers IGF-1 Protein and energy drive IGF-1
🏃 Exercise Resistance training 3-4x/week; stimulates growth hormone and IGF-1 release Strength training raises IGF-1
😴 Sleep Prioritize deep sleep (7-9 hrs); GH/IGF-1 release peaks during slow-wave sleep GH is sleep-dependent

Evidence-Backed Supplements

When Low

  • Protein Tier A May Increase

    Adequate protein intake supports IGF-1 levels

    Whey protein 1.2–2.0 g/kg/day Distributed across meals
    PMID 32483625
  • Zinc Tier B May Increase

    Zinc deficiency reduces IGF-1; replacement restores levels

    Zinc picolinate 15–30 mg/day Between meals
    PMID 33724446 PMID 36994923 PMID 27996088

Questions to Ask Your Doctor

  • Should we check growth hormone and consider pituitary imaging? Rules out acromegaly
  • Could this explain my muscle loss or slow recovery? Low IGF-1 affects body composition

Upload your blood test to see how your IGF-1 compares to reference and optimal ranges.

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